PAPER Yahata N, Asai M, Kitaoka S, Takahashi K, Asaka I, Hioki H, Kaneko T, Maruyama K, Saido TC, Nakahata T, Asada T, Yamanaka S, Iwata N, Inoue H

Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.

PLoS One. 2011;6(9):e25788. PubMed: 21984949

PAPER Ketelaar M, Hofstra R, Hayden M

What monozygotic twins discordant for phenotype illustrate about mechanisms influencing genetic forms of neurodegeneration.

Clin Genet. 2011 Oct 7; PubMed: 21981075

PAPER Delay C, Calon F, Mathews P, Hébert SS

Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function.

Mol Neurodegener. 2011;6:70. PubMed: 21982160

PAPER Williams RJ, Spencer JP

Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease.

Free Radic Biol Med. 2012 Jan 1;52(1):35-45. PubMed: 21982844

PAPER Dolan PJ, Jin YN, Hwang W, Johnson GV

Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.

FEBS Lett. 2011 Nov 4;585(21):3424-9. PubMed: 21983102

PAPER Samakashvili S, Ibáñez C, Simó C, Gil-Bea FJ, Winblad B, Cedazo-Mínguez A, Cifuentes A

Analysis of chiral amino acids in cerebrospinal fluid samples linked to different stages of Alzheimer disease.

Electrophoresis. 2011 Oct;32(19):2757-64. PubMed: 21983823

PAPER Timm T, von Kries JP, Li X, Zempel H, Mandelkow E, Mandelkow EM

Microtubule affinity regulating kinase activity in living neurons was examined by a genetically encoded fluorescence resonance energy transfer/fluorescence lifetime imaging-based biosensor: inhibitors with therapeutic potential.

J Biol Chem. 2011 Dec 2;286(48):41711-22. PubMed: 21984823

David Axelson

Redmond, United States

ann cooper

United States

PAPER Cleland WP

The role of surgery in coronary artery disease.

Postgrad Med J. 1976 Jul;52(609):462-3. PubMed: 9625

PAPER McManus ME, Ilett KF

Mixed function oxidase activity in a marsupial. The quokka (Seton;x brachyurus).

Drug Metab Dispos. 1976 May-Jun;4(3):199-202. PubMed: 6222

Ajeet Rijal

Germany

Australia Report: Inflammation

CONFERENCE COVERAGE 2011-10-11 Conference Coverage The role of the immune system in Alzheimer’s disease (AD) remains poorly understood, in part because the tools are not at hand to distinguish myeloid-derived cells from microglia, the brain’s resident phagocytes. The field also needs b

Pam McClean on Modeling Sporadic PD in a Dish?

COMMENT I think this paper adds to the increasing literature on the consequences of extracellular α-synuclein and its role in PD pathogenesis. It represents an important validation of several recent studies showing that α-synuclein can be taken up by neurons from

Pam McClean

Massachusetts General Hospital/Harvard Medical School
Charlestown, United States