Glenda Halliday

University of New South Wales & Neuroscience Research Australia
Randwick, Australia

Mathias Jucker on Toxic Synuclein Corrupts Native in Wild-Type Mice

COMMENT These are very impressive results from Virginia Lee and colleagues, and build on the previous work of the same group. The fact that synthetic material can act as a seed in wild-type mice opens a myriad of experimental approaches and avoids confounding fac

Eliezer Masliah on Toxic Synuclein Corrupts Native in Wild-Type Mice

COMMENT This is a very important paper that further supports the role of a prion-like propagation of proteins involved in neurodegenerative disorders. This is the first study that has been able to show propagation of α-synuclein after a single injection in non-tr

Benjamin Dehay on Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.

COMMENT Impairment of autophagy-lysosomal pathways is increasingly regarded as a major pathogenic event in neurodegenerative diseases, including Parkinson’s disease (PD). This new paper from Ishrat Ahmed and colleagues emphasizes once again that autophagy is an i

Benjamin Dehay

Institut des Maladies Neurodégénératives Université Bordeaux
Bordeaux, France

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The molecular pathophysiology of concussive brain injury.

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Seynab Sangsari

Germany

Meet the New Progressive Tauopathy: CTE in Athletes, Soldiers

CONFERENCE COVERAGE 2012-11-20 Conference Coverage When autopsies of football stars and wrestlers who had committed suicide touched off a storm of media coverage some years ago, the initial story was one of concussions putting athletes at risk for Alzheimer’s disease. Since then, howev

Prashanthi Vemuri on Multimodal Imaging: Structure, Function, Amyloid Not in Synch

COMMENT In this study, multimodal imaging data from the same subjects provide the authors with a unique opportunity to investigate the regional specificity of different Alzheimer’s disease pathologies. The study presents an approach to systematically put the mult

PAPER Hedden T, Van Dijk KR, Shire EH, Sperling RA, Johnson KA, Buckner RL

Failure to modulate attentional control in advanced aging linked to white matter pathology.

Cereb Cortex. 2012 May;22(5):1038-51. PubMed: 21765181