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TDP-43 Turns Itself Off, Inclusions a False Lead

RESEARCH NEWS 2011-01-20 Research News It is so easy to point the finger at conglomerates. In the brain, large inclusions of proteins—be they amyloid-β, α-synuclein, or TDP-43—just look like trouble. But lately, they are starting to look less culpable. In the case of the ubiquiti

Committee Shoots Down Florbetapir, Raising Bar for Field at Large

RESEARCH NEWS 2011-01-20 Research News The FDA’s Peripheral and Central Nervous System Drugs Advisory Committee today voted 13 to 3 to reject Avid Radiopharmaceutical’s New Drug Application for their amyloid imaging agent AV-45/florbetapir/Amyvid in its current form. They softene

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