SEARCH RESULTS
330907 RESULTS
Sree Ram Ganti
Chisinau, Moldova, Republic of
PAPER Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD
Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
J Neurosci Res. 2014 Nov;92(11):1581-90. Epub 2014 Jun 5 PubMed: 24903973PAPER Del Prete D, Checler F, Chami M
Ryanodine receptors: physiological function and deregulation in Alzheimer disease.
Mol Neurodegener. 2014 Jun 5;9:21. PubMed: 24902695PAPER Hamada Y, Ishiura S, Kiso Y
BACE1 Inhibitor Peptides: Can an Infinitely Small k cat Value Turn the Substrate of an Enzyme into Its Inhibitor?
ACS Med Chem Lett. 2012 Mar 8;3(3):193-7. Epub 2011 Dec 26 PubMed: 24900449PAPER Huang X, Zhou W, Liu X, Li H, Sun G, Mandal M, Vicarel M, Zhu X, Bennett C, McCraken T, Pissarnitski D, Zhao Z, Cole D, Gallo G, Zhu Z, Palani A, Aslanian R, Clader J, Czarniecki M, Greenlee W, Burnett D, Cohen-Williams M, Hyde L, Song L, Zhang L, Chu I, Buevich A
Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease.
ACS Med Chem Lett. 2012 Nov 8;3(11):931-5. Epub 2012 Sep 4 PubMed: 24900409PAPER Fuller NO, Hubbs JL, Austin WF, Creaser SP, McKee TD, Loureiro RM, Tate B, Xia W, Ives JL, Findeis MA, Bronk BS
Initial Optimization of a New Series of γ-Secretase Modulators Derived from a Triterpene Glycoside.
ACS Med Chem Lett. 2012 Nov 8;3(11):908-13. Epub 2012 Aug 29 PubMed: 24900406PAPER Wu WL, Domalski M, Burnett DA, Josien H, Bara T, Rajagopalan M, Xu R, Clader J, Greenlee WJ, Brunskill A, Hyde LA, Del Vecchio RA, Cohen-Williams ME, Song L, Lee J, Terracina G, Zhang Q, Nomeir A, Parker EM, Zhang L
Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease.
ACS Med Chem Lett. 2012 Nov 8;3(11):892-6. Epub 2012 Apr 9 PubMed: 24900404PAPER Kaller MR, Harried SS, Albrecht B, Amarante P, Babu-Khan S, Bartberger MD, Brown J, Brown R, Chen K, Cheng Y, Citron M, Croghan MD, Graceffa R, Hickman D, Judd T, Kriemen C, La D, Li V, Lopez P, Luo Y, Masse C, Monenschein H, Nguyen T, Pennington LD, Miguel TS, Sickmier EA, Wahl RC, Weiss MM, Wen PH, Williamson T, Wood S, Xue M, Yang B, Zhang J, Patel V, Zhong W, Hitchcock S
A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase.
ACS Med Chem Lett. 2012 Nov 8;3(11):886-91. Epub 2012 Mar 29 PubMed: 24900403PAPER Blass B
5-Amino-oxazepine and 5-Amino-thiazepine Compounds as β-Secretase Antagonists and Methods of Use: Patent Highlight.
ACS Med Chem Lett. 2012 Nov 8;3(11):873-4. Epub 2012 Oct 29 PubMed: 24900396PAPER Qin J, Zhou W, Huang X, Dhondi P, Palani A, Aslanian R, Zhu Z, Greenlee W, Cohen-Williams M, Jones N, Hyde L, Zhang L
Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators.
ACS Med Chem Lett. 2011 Jun 9;2(6):471-6. Epub 2011 Mar 29 PubMed: 24900332PAPER Peng H, Talreja T, Xin Z, Cuervo JH, Kumaravel G, Humora MJ, Xu L, Rohde E, Gan L, Jung MY, Shackett MN, Chollate S, Dunah AW, Snodgrass-Belt PA, Arnold HM, Taveras AG, Rhodes KJ, Scannevin RH
Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator.
ACS Med Chem Lett. 2011 Oct 13;2(10):786-91. Epub 2011 Aug 5 PubMed: 24900267PAPER Huang X, Aslanian R, Zhou W, Zhu X, Qin J, Greenlee W, Zhu Z, Zhang L, Hyde L, Chu I, Cohen-Williams M, Palani A
The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators.
ACS Med Chem Lett. 2010 Jul 8;1(4):184-7. Epub 2010 May 24 PubMed: 24900193PAPER Gillman KW Jr, Starrett JE Jr, Parker MF, Xie K, Bronson JJ, Marcin LR, McElhone KE, Bergstrom CP, Mate RA, Williams R, Meredith JE, Burton CR, Barten DM, Toyn JH, Roberts SB, Lentz KA, Houston JG, Zaczek R, Albright CF, Decicco CP, Macor JE, Olson RE
Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor.
ACS Med Chem Lett. 2010 Jun 10;1(3):120-4. Epub 2010 Mar 22 PubMed: 24900185PAPER Zarbiv Y, Simhi-Haham D, Israeli E, Elhadi SA, Grigoletto J, Sharon R
Lysine residues at the first and second KTKEGV repeats mediate α-Synuclein binding to membrane phospholipids.
Neurobiol Dis. 2014 Oct;70:90-8. Epub 2014 Jun 4 PubMed: 24905915Current Filters
No filters selected