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PAPER Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I

Microglia development follows a stepwise program to regulate brain homeostasis.

Science. 2016 Aug 19;353(6301):aad8670. Epub 2016 Jun 23 PubMed: 27338705

Aging Causes “Identity Crisis” in Glia

RESEARCH NEWS 2017-01-21 Research News Aging can do a number on the human brain. Thinking slows, concentration flags, and memory can falter. A study in the January 10 Cell Reports uncovers a dramatic difference between how neurons and glia, the brain’s supporting cells, deal with ...

Building Better Mouse Models for Late-Onset Alzheimer’s

RESEARCH NEWS 2017-01-20 Research News Why do so many promising Alzheimer’s therapies perform well in mice but fail in clinical trials? Scientists lay some of the blame on the lack of good mouse models for late-onset disease, as well as discrepancies between the outcomes used in ...

Microglia Give Astrocytes License to Kill

RESEARCH NEWS 2017-01-20 Research News In their healthy state, astrocytes busy themselves nursing neurons—forming and pruning synapses, clearing used neurotransmitters, and delivering nutrients. Now, a paper in the January 18 Nature reports that three cytokines released by ...

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