RESEARCH MODELS Modification Details Transgene containing human PSEN2 carrying the N141I mutation driven by the neuron-specific enolase (NSE) promoter. Neuropathology Not observed. Cognition/Behavior Behavioral deficits in the water maze at 12 months in mice expressing m
THERAPEUTICS Lundbeck Otsuka Pharmaceutical Co., Ltd. Rexulti OPC 34712 Small Molecule Other Neurotransmitters In July 2013, Otsuka and Lundbeck started a Phase 3 study in the U.S., Europe, and Russia to evaluate brexpiprazole for the treatment of agitation in 560 pat
Theorectical Neuroscience Research, LLCRidgeland, United States
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RetiredCleveland, United States
United States
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