PAPER Amin RA, Robertson NP
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PAPER Geed M, Garabadu D, Ahmad A, Krishnamurthy S
Silibinin pretreatment attenuates biochemical and behavioral changes induced by intrastriatal MPP(+) injection in rats.
Pharmacol Biochem Behav. 2013 Dec 15;117C PubMed: 24345573PAPER Ghezzi L, Scarpini E, Galimberti D
Disease-modifying drugs in Alzheimer's disease.
Drug Des Devel Ther. 2013 Dec 6;7:1471-8. PubMed: 24353405PAPER Caso F, Mandelli ML, Henry M, Gesierich B, Bettcher BM, Ogar J, Filippi M, Comi G, Magnani G, Sidhu M, Trojanowski JQ, Huang EJ, Grinberg LT, Miller BL, Dronkers N, Seeley WW, Gorno-Tempini ML
In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology.
Neurology. 2014 Jan 21;82(3):239-47. Epub 2013 Dec 18 PubMed: 24353332PAPER Villemagne VL, Ng S, Cappai R, Barnham KJ, Fodero-Tavoletti MT, Rowe CC, Masters CL
La lunga attesa: towards a molecular approach to neuroimaging and therapeutics in Alzheimer's disease.
Neuroradiol J. 2006 Oct 19;19(4):453-74. PubMed: 24351248PAPER De Montigny A, Elhiri I, Allyson J, Cyr M, Massicotte G
NMDA reduces Tau phosphorylation in rat hippocampal slices by targeting NR2A receptors, GSK3β, and PKC activities.
Neural Plast. 2013;2013:261593. Epub 2013 Nov 20 PubMed: 24349798Merck BACE Inhibitor Clears a Safety Hurdle, Gets New Trial
RESEARCH NEWS 2013-12-19 Research News On December 10, Merck announced that its BACE inhibitor, MK-8931, had met initial safety requirements in the Phase 2/3 EPOCH study of patients with mild to moderate Alzheimer’s disease. Not only will the company proceed with this large t
Wadim Kapulkin
MPI-CBGDresden, Germany
Drug Discovery for Neurodegeneration: An Intensive Course on Translating Research into Drugs, 2014
CONFERENCE 2014-02-02 00:00:00-2014-02-04 00:00:00 Miami Beach Resort, Miami, FL, U.S.A. 02 February 2014 to 04 February 2014 Designed as a comprehensive course on the drug discovery process, from target validation through to clinical development, the annual Drug Discovery for Neurodegeneration conference
Deborah Dhuyvetter
Janssen PharmaceuticalsBelgium
Louis Grossman
Miami, United States
PAPER Balmaceda V, Cuchillo-Ibáñez I, Pujadas L, García-Ayllón MS, Saura CA, Nimpf J, Soriano E, Sáez-Valero J
ApoER2 processing by presenilin-1 modulates reelin expression.
FASEB J. 2014 Apr;28(4) Epub 2013 Dec 16 PubMed: 24344333PAPER Yu Y, Logovinsky V, Schuck E, Kaplow J, Chang MK, Miyagawa T, Wong N, Ferry J
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel γ-secretase modulator, E2212, in healthy human subjects.
J Clin Pharmacol. 2013 Dec 17; PubMed: 24343761PAPER Chen CY, Liao YF, Chang MY, Hu MK
Difluorophenylglycinols as new modulators of proteolytic processing of amyloid precursor proteins.
Arch Pharm (Weinheim). 2014 Mar;347(3):161-73. Epub 2013 Dec 11 PubMed: 24339192PAPER Acx H, Chávez-Gutiérrez L, Serneels L, Lismont S, Benurwar M, Elad N, De Strooper B
Signature amyloid β profiles are produced by different γ-secretase complexes.
J Biol Chem. 2014 Feb 14;289(7):4346-55. Epub 2013 Dec 13 PubMed: 24338474Current Filters
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