PAPER Maki Y, Yamaguchi T, Yamaguchi H
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PAPER El Haj M, Kessels RP
Context memory in Alzheimer's disease.
Dement Geriatr Cogn Dis Extra. 2013;3(1):342-50. Epub 2013 Oct 5 PubMed: 24403906PAPER Perez-Garmendia R, Gevorkian G
Pyroglutamate-Modified Amyloid Beta Peptides: Emerging Targets for Alzheimer´s Disease Immunotherapy.
Curr Neuropharmacol. 2013 Sep;11(5):491-8. PubMed: 24403873PAPER Liu X, Teng Z, Cui C, Wang R, Liu M, Zhang Y
Amyloid beta-derived diffusible ligands (ADDLs) induce abnormal expression of insulin receptors in rat hippocampal neurons.
J Mol Neurosci. 2014 Jan;52(1):124-30. Epub 2014 Jan 10 PubMed: 24402880PAPER Catalá-López F, Crespo-Facorro B, Vieta E, Valderas JM, Valencia A, Tabarés-Seisdedos R
Alzheimer's disease and cancer: current epidemiological evidence for a mutual protection.
Neuroepidemiology. 2014;42(2):121-2. Epub 2014 Jan 3 PubMed: 24401794PAPER Abner EL, Nelson PT, Schmitt FA, Browning SR, Fardo DW, Wan L, Jicha GA, Cooper GE, Smith CD, Caban-Holt AM, Van Eldik LJ, Kryscio RJ
Self-Reported Head Injury and Risk of Late-Life Impairment and AD Pathology in an AD Center Cohort.
Dement Geriatr Cogn Disord. 2014;37(5-6):294-306. Epub 2013 Dec 31 PubMed: 24401791PAPER Cutuli D, De Bartolo P, Caporali P, Tartaglione AM, Oddi D, D'Amato FR, Nobili A, D'Amelio M, Petrosini L
Neuroprotective effects of donepezil against cholinergic depletion.
Alzheimers Res Ther. 2013 Oct 24;5(5):50. PubMed: 24401551PAPER Windisch M
We can treat Alzheimer's disease successfully in mice but not in men: failure in translation? A perspective.
Neurodegener Dis. 2014;13(2-3):147-50. Epub 2014 Jan 7 PubMed: 24401335PAPER Van Dijk D
Long-term cognitive impairment after critical illness.
N Engl J Med. 2014 Jan 9;370(2):185. PubMed: 24401071PAPER Fraser GL, Riker RR, Coursin DC
Long-term cognitive impairment after critical illness.
N Engl J Med. 2014 Jan 9;370(2):184. PubMed: 24401070PAPER Pandharipande PP, Girard TD, Ely EW
Long-term cognitive impairment after critical illness.
N Engl J Med. 2014 Jan 9;370(2):185-6. PubMed: 24401069Michael Siciliano
Arlington, United States
Douglas Galasko on Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial.
COMMENT The TEAM-AD study revives interest in two areas: treatment with antioxidants such as vitamin E, and carrying out clinical trials in patients with mild to moderate AD to evaluate effects on disease progression. The findings of a benefit in the vitamin E tr
Benjamin Wolozin on Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.
COMMENT This is a great article. The approach makes classic use of genetics to identify TDP-43 interactors, and in the process identifies a number of previously known and unknown players. The most interesting parts of the article for me are the experiments modula
Kurt A. Jellinger on Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study.
COMMENT Mielke et al. found that among older people with MCI but not cognitively normal (CN) individuals, those with a previous history of traumatic brain injury (TBI) have more Aß deposits in the brain than those without TBI history, suggesting that the etiology
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