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PSEN1 L271V

MUTATIONS PSEN1 73664780 GRCh37/hg19 rs63750886 C G g.49996C> G g.66602C> G Exon 8 Point, Missense Coding   Affects splicing of exon 8 such that more transcripts are produced which lack exon 8. Causes amino acid replacement (D257A) at the splice junction of e

G8 to Set Sights on Dementia

RESEARCH NEWS 2013-05-31 Research News This June, leaders from the globe’s eight richest countries, the G8, will assemble in Northern Ireland to discuss major issues related to the world’s economy—among them, the rising threat of dementia in aging populations. U.K. Prime Minister

Does Shrinking Temporal Lobe Make AD Patients Overly Sensitive?

RESEARCH NEWS 2013-05-31 Research News Though typically seen as a cognitive disorder, Alzheimer’s disease can throw emotions off kilter, making people unusually sensitive to others’ feelings and moods. New research suggests biological underpinnings for such changes. A report in t

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