175128 RESULTS

TREM2 Buoys Microglial Disaster Relief Efforts in AD and Stroke

RESEARCH NEWS 2015-02-28 Research News When the going gets tough, microglia rely on TREM2 to get going. That was the common conclusion from two papers that investigated the role of the myeloid receptor in mouse models of Alzheimer’s disease and stroke. One study, led by Marco ...

Consortium Debuts Biggest Set of Human Epigenomes To Date

RESEARCH NEWS 2015-02-27 Research News A consortium of 258 researchers at 41 institutions, having completed 2,800 experiments and sequenced 150 billion DNA fragments over seven years, now presents the human epigenome. In the February 19 Nature, corresponding author Manolis Kellis ...

BACE Inhibitor Trial Put on Hold

RESEARCH NEWS 2015-02-27 Research News Vitae Pharmaceuticals announced on 26 February the temporary suspension of Phase I clinical testing of BI 1181181. This β-secretase (BACE) inhibitor is being developed by Boehringer Ingelheim and evaluated jointly with Vitae. Few details are ...

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