PAPER Ott S, Henkel AW, Henkel MK, Redzic ZB, Kornhuber J, Wiltfang J
SEARCH RESULTS
329930 RESULTS
Elizabeth Heilig on Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates.
COMMENT In this study, Gong et al. have conducted a careful, systematic analysis of the role of PS1 luminal loop 1 (LL1) and the adjacent transmembrane region, TM2, in γ-secretase complex formation, presenilinase cleavage, and substrate cleavage activity using a
Yuli Wang
Gerontologist, Instructor certified for Dementia Care Practitioner)Chatsworth, United States