RESEARCH NEWS 2016-10-28 Add Private note Add An editorial note Research News Genetic variants in the BIN1 gene increase risk for late-onset Alzheimer’s disease. Scientists want to know why, and a paper in the October 18 Cell Reports blames tau. Researchers led by Patrik ...
PAPER Pant S, Sharma M, Patel K, Caplan S, Carr CM, Grant BD19915558
Spring, United States
COMMENT These two papers present a comprehensive addition to our knowledge of the mechanisms of action of C9ORF72 dipeptide repeats. Studying other protein aggregates, investigators identified a plethora of protein interactions, which lead to the general ...
COMMENT These papers convincingly argue that toxicity due to C9ORF72 GGGGCC repeat expansions arises from arginine dipeptide repeats (DPRs) interactions with proteins containing low-complexity domain (LCDs) inside ribonucleoprotein granule membrane-less ...
PAPER Subudhi BB, Sahu PK
Angiotensin Mediated Oxidative Stress and Neuroprotective Potential of Antioxidants and AT1 Receptor Blockers.Mini Rev Med Chem. 2016 Oct 24; PubMed: 27781960
PAPER Malik R, Choudhary BS, Srivastava S, Mehta P, Sharma M
Identification of novel Acetylcholinesterase inhibitors through e-pharmacophore based virtual screening and molecular dynamics simulations.J Biomol Struct Dyn. 2016 Oct 26;:1-29. PubMed: 27782777
PAPER Ram S27780988
PAPER Pchelina S, Emelyanov A, Baydakova G, Andoskin P, Senkevich K, Nikolaev M, Miliukhina I, Yakimovskii A, Timofeeva A, Fedotova E, Abramycheva N, Usenko T, Kulabukhova D, Lavrinova A, Kopytova A, Garaeva L, Nuzhnyi E, Illarioshkin S, Zakharova E
Oligomeric α-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson's disease.Neurosci Lett. 2016 Oct 22; PubMed: 27780739
PAPER Cheng L, Zhang J, Li XY, Yuan L, Pan YF, Chen XR, Gao TM, Qiao JT, Qi JS
A Novel Antibody Targeting Sequence 31-35 in Amyloid β Protein Attenuates Alzheimer's Disease-Related Neuronal Damage.Hippocampus. 2016 Oct 26; PubMed: 27784133
PAPER Sağlık BN, Ilgın S, Özkay Y27783974
PAPER Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ
Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.Cell Rep. 2016 Oct 25;17(5):1227-1237. PubMed: 27783938
PAPER Kövari E, Herrmann FR, Gold G, Hof PR, Charidimou A27783888
PAPER Tan X, Fang P, An J, Lin H, Liang Y, Shen W, Leng X, Zhang C, Zheng Y, Qiu S
Micro-structural white matter abnormalities in type 2 diabetic patients: a DTI study using TBSS analysis.Neuroradiology. 2016 Oct 25; PubMed: 27783100
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