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Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51.

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms.

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PAPER Delacourte A, Flament S, Dibe EM, Hublau P, Sablonnière B, Hémon B, Shérrer V, Défossez A

Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease. Demonstration with a panel of antibodies against Tau proteins.

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Does TauRx Drug Work by Oxidizing Tau?

RESEARCH NEWS 2013-02-21 Research News In 2008, Rember ™, aka methylene blue, created a stir when the drug’s sponsors reported that it slowed cognitive decline in a Phase 2 trial for Alzheimer’s disease, while other scientists questioned that interpretation (see ARF related news

PAPER Fernández E, García-Moreno JM, Pablos AM, Chacón J

May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?

Antioxid Redox Signal. 2013 Mar 28; PubMed: 23418747

PAPER Yeh HH, Young D, Gelovani JG, Robinson A, Davidson Y, Herholz K, Mann DM

Histone deacetylase class II and acetylated core histone immunohistochemistry in human brains with Huntington's disease.

Brain Res. 2013 Apr 4;1504:16-24. PubMed: 23419892

PAPER Milanesi E, Bonvicini C, Alberici A, Pilotto A, Cattane N, Premi E, Gazzina S, Archetti S, Gasparotti R, Cancelli V, Gennarelli M, Padovani A, Borroni B

Molecular signature of disease onset in Granulin mutation carriers: a gene expression analysis study.

Neurobiol Aging. 2013 Jul;34(7):1837-45. PubMed: 23419701

PAPER Maniwang E, Tayebi N, Sidransky E

Is Parkinson disease associated with lysosomal integral membrane protein type-2?: challenges in interpreting association data.

Mol Genet Metab. 2013 Apr;108(4):269-71. PubMed: 23419877

PAPER Parnetti L, Castrioto A, Chiasserini D, Persichetti E, Tambasco N, El-Agnaf O, Calabresi P

Cerebrospinal fluid biomarkers in Parkinson disease.

Nat Rev Neurol. 2013 Mar;9(3):131-40. PubMed: 23419373

PAPER Chan FT, Kaminski Schierle GS, Kumita JR, Bertoncini CW, Dobson CM, Kaminski CF

Protein amyloids develop an intrinsic fluorescence signature during aggregation.

Analyst. 2013 Apr 7;138(7):2156-62. PubMed: 23420088

PAPER Darawi MN, Ai-Vyrn C, Ramasamy K, Hua PP, Pin TM, Kamaruzzaman SB, Majeed AB

Allele-specific polymerase chain reaction for the detection of Alzheimer's disease-related single nucleotide polymorphisms.

BMC Med Genet. 2013;14:27. PubMed: 23419238

PAPER Sinha N, Grimes D, Tokuhiro S, Sato C, Rogaeva E, Woulfe J

Variant Alzheimer's disease with spastic paraparesis and supranuclear gaze palsy.

Can J Neurol Sci. 2013 Mar;40(2):249-51. PubMed: 23419577

PAPER Cheng D, Logge W, Low JK, Garner B, Karl T

Novel behavioural characteristics of the APP(Swe)/PS1ΔE9 transgenic mouse model of Alzheimer's disease.

Behav Brain Res. 2013 May 15;245:120-7. PubMed: 23419740

PAPER Gray SL, Anderson ML, Hubbard RA, Lacroix A, Crane PK, McCormick W, Bowen JD, McCurry SM, Larson EB

Frailty and Incident Dementia.

J Gerontol A Biol Sci Med Sci. 2013 Feb 18; PubMed: 23419778

PAPER Andreasson U, Lautner R, Schott JM, Mattsson N, Hansson O, Herukka SK, Helisalmi S, Ewers M, Hampel H, Wallin A, Minthon L, Hardy J, Blennow K, Zetterberg H

CSF biomarkers for Alzheimer's pathology and the effect size of APOE ɛ4.

Mol Psychiatry. 2013 Feb 19; PubMed: 23419830