PAPER Takahashi RH, Tobiume M, Sato Y, Sata T, Gouras GK, Takahashi H
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PAPER Pollen DA, Baker S, Hinerfeld D, Swearer J, Evans BA, Evans JE, Caselli R, Rogaeva E, St George-Hyslop P, Moonis M
Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4.
Alzheimers Res Ther. 2010;2(5):31. PubMed: 21062519PAPER Seng BK, Luo N, Ng WY, Lim J, Chionh HL, Goh J, Yap P
Validity and reliability of the Zarit Burden Interview in assessing caregiving burden.
Ann Acad Med Singapore. 2010 Oct;39(10):758-63. PubMed: 21063635PAPER Xiao H, Su Y, Cao X, Sun S, Liang Z
A meta-analysis of mood stabilizers for Alzheimer's disease.
J Huazhong Univ Sci Technolog Med Sci. 2010 Oct;30(5):652-8. PubMed: 21063851PAPER Robins Wahlin TB, Byrne GJ
Personality changes in Alzheimer's disease: a systematic review.
Int J Geriatr Psychiatry. 2010 Nov 9; PubMed: 21064117PAPER Diamond J
Social science. The benefits of multilingualism.
Science. 2010 Oct 15;330(6002):332-3. PubMed: 20947754AMPKα, phos Thr172
ANTIBODY polyclonal manufacturer Cat# ab51110<br />Reference: <br /><a href="/papers/ampk-abnormally-activated-tangle-and-pre-tangle-bearing-neurons-alzheimers-disease-and-other" target="_new">Vingtdeux, 2010</a> immunog
PAPER Simonini MV, Polak PE, Sharp A, McGuire S, Galea E, Feinstein DL
Increasing CNS noradrenaline reduces EAE severity.
J Neuroimmune Pharmacol. 2010 Jun;5(2):252-9. PubMed: 19957206PAPER Bondareff W, Mountjoy CQ, Roth M
Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia.
Neurology. 1982 Feb;32(2):164-8. PubMed: 7198741PAPER Mann DM, Lincoln J, Yates PO, Stamp JE, Toper S
Changes in the monoamine containing neurones of the human CNS in senile dementia.
Br J Psychiatry. 1980 Jun;136:533-41. PubMed: 6155966PAPER Ritz B, Rhodes SL, Qian L, Schernhammer E, Olsen JH, Friis S
L-type calcium channel blockers and Parkinson disease in Denmark.
Ann Neurol. 2010 May;67(5):600-6. PubMed: 20437557PAPER Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, Roebuck SJ, Morrison A, Pickering S, Clapham JC, Brand MD
Superoxide activates mitochondrial uncoupling proteins.
Nature. 2002 Jan 3;415(6867):96-9. PubMed: 11780125PAPER Guzman JN, Sánchez-Padilla J, Chan CS, Surmeier DJ
Robust pacemaking in substantia nigra dopaminergic neurons.
J Neurosci. 2009 Sep 2;29(35):11011-9. PubMed: 19726659Yadong Huang on Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene.
COMMENT The ε4 allele of apolipoprotein (Apo) E is the major susceptibility gene for late-onset Alzheimer’s disease (AD). In most clinical studies, ApoE4 carriers account for 65-80 percent of all late-onset AD cases (1), highlighting the importance of ApoE4 in AD
Masato Hasegawa on Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.
COMMENT The paper by Julie Harris and colleagues is an important contribution toward understanding the role of synaptic networks in progression of neuronal dysfunction and Aβ deposition. They produced and studied transgenic mouse models with region-specific overe
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