Benzodiazepines Boost Risk of Alzheimer’s Disease

RESEARCH NEWS 2014-09-16 Research News Valium can make people pleasantly foggy, which is a reason doctors prescribe it to relieve stress during outpatient surgeries and for anxiety and panic attacks. However, a new study suggests that the effects of prolonged use of benzodiazepin

Ana Graf

ACI-24

THERAPEUTICS AC Immune SA ACI-24.060 Pal1-15 acetate salt Immunotherapy (active) Amyloid-Related In 2009, AC Immune began a Phase 1/2 trial of ACI-24 to evaluate safety, immunogenicity, and efficacy. Five sites in Finland, Sweden, and Denmark planned to enroll up to 1

ACI-35

THERAPEUTICS AC Immune SA Janssen VAC20121 JNJ-64042056 Immunotherapy (active) Tau In December 2013, AC Immune began the first human trial of a phospho-tau-specific vaccine. This Phase 1b study compared a six-month course of undisclosed low, medium, and high doses of

Helen Street

Bengt Winblad on Benzodiazepine use and risk of Alzheimer's disease: case-control study.

COMMENT As the authors state, it still cannot be ruled out that benzodiazepine use might be an early marker of a dementia disorder or a condition associated with an increased risk of dementia. Also, it is important to separate a possible long-term effect of these

Rebecca Gottesman on Angiotensin-neprilysin inhibition versus enalapril in heart failure.

COMMENT I think that certainly the PARADIGM results are very promising, and heart failure is likely an important contributor to cognitive decline, perhaps even independently of the underlying vascular disease that it represents. Some small studies suggest that pa