ASK1 (2D11)

ANTIBODY monoclonal 2D11 manufacturer Cat# YSRTMCA4797Z liquid, no preservative, ASK1/MAP3K5 Accurate Mouse ASK1 http://alzforum.org/res/com/ant/default.asp?antibodyID=35768

MEKK5/ ASK1

ANTIBODY polyclonal manufacturer Cat# AP7911f Immunogen = synthetic peptide corresp. to aa residues surrounding S966 of human MAP3K5, conj. KLH liquid, PBS, azide, Protein A/affinity purified MEKK5 /ASK1 ASK1/MAP3K5 ABGENT Rabbit Human Mouse MEKK5/ ASK1 http://alz

MEKK5/ ASK1

ANTIBODY polyclonal manufacturer Cat# AP7911e Immunogen = synthetic peptide corresp. to aa residues surrounding Ser83 of human MAP3K5, conj. KLH liquid, PBS, azide, Protein A/affinity purified MEKK5 /ASK1 ASK1/MAP3K5 ABGENT Rabbit Human MEKK5/ ASK1 http://alzforum

MEKK5/ ASK1

ANTIBODY polyclonal manufacturer Cat# AP7911d Immunogen = synthetic peptide corresp. to aa residues surrounding Ser1033 of human MAP3K5, conj. KLH liquid, PBS, azide, Protein A/affinity purified MEKK5 /ASK1 ASK1/MAP3K5 ABGENT Rabbit Human Mouse MEKK5/ ASK1 http://

ASK1 (A1)

ANTIBODY monoclonal A1 manufacturer Cat# ab89420 immunogen = recombinant fragment, corresp. to aa649- 946 of human ASK1 SwissProt:Q99683 liquid, PBS, no preservative, affinity purified recombinant fragment of ASK1 IgG ASK1/MAP3K5 Abcam Rabbit Human ASK1 http://alz

ASK1

ANTIBODY monoclonal manufacturer Cat# ab55704 immunogen = recombinant fragment, corresp. to aa1231-1374 of human ASK1 liquid, PBS, no preservative, protein G purified ASK1 IgG_2b, κ ASK1/MAP3K5 Abcam Rabbit Human ASK1 http://alzforum.org/res/

ASK1

ANTIBODY polyclonal manufacturer Cat# ab71430 Immunogen = synthetic peptide corresp. to aa residues surrounding Ser966 of human ASK1 conj. to KLH liquid, PBS, azide, protein A/affinity purified ASK1 IgG ASK1/MAP3K5 Abcam Rabbit Human ASK1 http://alzforum.org/res/c

ASK1

ANTIBODY polyclonal manufacturer Cat# ab62575 Immunogen = 16 aa peptide from near the C-terminus of human ASK1 liquid, PBS, azide, affinity purified ASK1 IgG ASK1/MAP3K5 Abcam Rabbit Human Mouse ASK1 http://alzforum.org/res/com/ant/default.asp?antibodyID=35761

Fred Van Leuven on Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

COMMENT I agree with the three previous commentators that the levels of Aβ used in these experiments are high. Then again, we have no idea what the Aβ content is in and around our neurons, or rather our synapses—the active ones that is—where Aβ is claimed to be p

Rudolf Bloechl on Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse

COMMENT The important result by Ittner et al. that post-synaptic targeting of the Src kinase Fyn depends on tau should also be relevant to p75-mediated Aβ toxicity. The observed prevention of Aβ toxicity in APP23 mice with absent or truncated tau could, in part,

Patricio F. Reyes on Untapped Resource? New Study to Boost Acceptance of CSF Analysis

COMMENT Other possible reasons why many clinicians hesitate to use lumbar puncture (LP) as a diagnostic test for AD and certain dementias include patient misconception that LP is a "dangerous" procedure, the cost of LP and care of its potential complica

Patricio F. Reyes

United States

Aβ fibrils, APP CTF (WO2)

ANTIBODY monoclonal WO2 laboratory WO2<br />(<a href="http://www.biomedexperts.com/Profile.bme/1057193/Brian_O_Nuallain" target="_new">Brian O'Nuallain</a>,<br />Graduate School of Medicine, University of Tennessee

Allen Buhl

Portage, United States

Aβ fibrils (WO1)

ANTIBODY monoclonal WO1 laboratory raised against sonicated amyloid fibrils grown from synthesized Aβ1–40 peptides (epitope within aa 1-16) detects amyloid-beta fibrils; exhibits binding to fibrils in the presence of a large excess of Aβ(1–40) monomer, suggesting