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New Ways to Target Aβ and BACE Show Promising Phase 1 Data

CONFERENCE COVERAGE 2016-08-24 Conference Coverage Amyloid β, in its various incarnations, remains a favorite target of big pharma. This year’s AAIC meeting, held July 22-28 in Toronto, saw the arrival of both new BACE inhibitors and the first therapeutic antibody against pyroglutamate ...

Tackling Mutant C9ORF72 Transcripts at the Source

RESEARCH NEWS 2016-08-23 Research News Some patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) carry a long repeat expansion in the C9ORF72 gene. Those stretches of DNA can be transcribed in both sense and antisense directions, leading to the ...

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