PAPER Cohen AD, Price JC, Mathis CA, Nebes RD, Saxton JA, Snitz BE, Aizenstein HJ, Weissfeld LA, DeKosky ST, Klunk WE
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Bradley Hyman on Seeing Is Believing—Plaque Growth Is Slow, Tapers With Age
COMMENT Several papers now have used multiphoton imaging to monitor plaques over time in AD transgenic models (Hefendehl et al., 2011; Burgold et al., 2010; Yan et al., 2009), following on the initial work we published in 2001 (Christie et al., 2001). Over the ye
PAPER Bateman A, Bennett HP
The granulin gene family: from cancer to dementia.
Bioessays. 2009 Nov;31(11):1245-54. PubMed: 19795409PAPER Forgac M
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology.
Nat Rev Mol Cell Biol. 2007 Nov;8(11):917-29. PubMed: 17912264PAPER Auer KL, Jacobson BS
Beta 1 integrins signal lipid second messengers required during cell adhesion.
Mol Biol Cell. 1995 Oct;6(10):1305-13. PubMed: 8573788PAPER Jeyakumar M, Thomas R, Elliot-Smith E, Smith DA, van der Spoel AC, d'Azzo A, Perry VH, Butters TD, Dwek RA, Platt FM
Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.
Brain. 2003 Apr;126(Pt 4):974-87. PubMed: 12615653PAPER Auer IA, Schmidt ML, Lee VM, Curry B, Suzuki K, Shin RW, Pentchev PG, Carstea ED, Trojanowski JQ
Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease.
Acta Neuropathol. 1995;90(6):547-51. PubMed: 8615074Back to Basics? Boosting pH Puts Cells in Progranulin-Pumping Mode
RESEARCH NEWS 2011-02-06 Research News For people with mutations in progranulin that lead to frontotemporal dementia, the problem is one of production—they have one good progranulin gene, but it cannot make enough of the protein. In the February 2 Journal of Neuroscience, scienti
A Surfeit of Sphingolipids Sours Aβ Digestion
RESEARCH NEWS 2011-02-06 Research News The ancient Sphinx posed riddles to travelers before devouring them. Sphingolipids, the Sphinx’s modern namesake, may hold clues to the riddle of why some neurons fail to digest Aβ. In this week’s Journal of Neuroscience, researchers led by
PAPER Casanova R, Espeland MA, Goveas JS, Davatzikos C, Gaussoin SA, Maldjian JA, Brunner RL, Kuller LH, Johnson KC, Mysiw WJ, Wagner B, Resnick SM,
Application of machine learning methods to describe the effects of conjugated equine estrogens therapy on region-specific brain volumes.
Magn Reson Imaging. 2011 May;29(4):546-53. PubMed: 21292420PAPER Bell KF, Hardingham GE
The influence of synaptic activity on neuronal health.
Curr Opin Neurobiol. 2011 Apr;21(2):299-305. PubMed: 21292474PAPER Jeong GB, Mojsilovic-Petrovic J, Boccitto M, Kalb R
Signaling events in axons and/or dendrites render motor neurons vulnerable to mutant superoxide dismutase toxicity.
J Neurosci. 2011 Jan 5;31(1):295-9. PubMed: 21209215PAPER Gutierrez-Merino C, Lopez-Sanchez C, Lagoa R, Samhan-Arias AK, Bueno C, Garcia-Martinez V
Neuroprotective actions of flavonoids.
Curr Med Chem. 2011;18(8):1195-212. PubMed: 21291366PAPER Danielyan L 2nd, Schäfer R, von Ameln-Mayerhofer A, Bernhard F, Verleysdonk S, Buadze M, Lourhmati A, Klopfer T, Schaumann F, Schmid B, Koehle C, Proksch B, Weissert R, Reichardt HM, van den Brandt J, Buniatian GH, Schwab M, Gleiter CH, Frey WH
Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.
Rejuvenation Res. 2011 Feb;14(1):3-16. Epub 2011 Feb 3 PubMed: 21291297PAPER Lavdas AA, Papastefanaki F, Thomaidou D, Matsas R
Cell adhesion molecules in gene and cell therapy approaches for nervous system repair.
Curr Gene Ther. 2011 Apr;11(2):90-100. PubMed: 21291359Current Filters
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