N. Picard

ABBOTT
France

PAPER Dunaev NB, Prigorodov VI

[Regional conference on the problems of the epidemiology, clinical picture, pathogenesis and treatment of mixed infections].

Zh Mikrobiol Epidemiol Immunobiol. 1978 Nov;(11):148. PubMed: 31751

PAPER Bedini L, Denoth F, Contini C

Measuring the stimulating energy threshold in living tissues.

TIT J Life Sci. 1978;8(1-2):37-40. PubMed: 741460

PAPER Williams TJ, Mitterling KL, Thompson LI, Torres-Reveron A, Waters EM, McEwen BS, Gore AC, Milner TA

Age- and hormone-regulation of opioid peptides and synaptic proteins in the rat dorsal hippocampal formation.

Brain Res. 2011 Mar 16;1379:71-85. PubMed: 20828542

PAPER Taranukhin AG, Taranukhina EY, Saransaari P, Podkletnova IM, Pelto-Huikko M, Oja SS

Neuroprotection by taurine in ethanol-induced apoptosis in the developing cerebellum.

J Biomed Sci. 2010;17 Suppl 1:S12. PubMed: 20804586

PAPER Kubera M, Obuchowicz E, Goehler L, Brzeszcz J, Maes M

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):744-59. PubMed: 20828592

PAPER Ferri A, Fiorenzo P, Nencini M, Cozzolino M, Pesaresi MG, Valle C, Sepe S, Moreno S, Carrì MT

Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.

Hum Mol Genet. 2010 Nov 15;19(22):4529-42. PubMed: 20829229

PAPER Peled A

The neurophysics of psychiatric diagnosis: clinical brain profiling.

Med Hypotheses. 2011 Jan;76(1):34-49. PubMed: 20828937

PAPER Meuvis J, Gerard M, Desender L, Baekelandt V, Engelborghs Y

The conformation and the aggregation kinetics of α-synuclein depend on the proline residues in its C-terminal region.

Biochemistry. 2010 Nov 2;49(43):9345-52. PubMed: 20828147

PAPER Kan I, Barhum Y, Melamed E, Offen D

Mesenchymal stem cells stimulate endogenous neurogenesis in the subventricular zone of adult mice.

Stem Cell Rev. 2011 Jun;7(2):404-12. PubMed: 20830611

Mordhwaj Parihar on Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5.

COMMENT In this paper, it is observed that membrane-attached oligomers of amyloid-β cause clustering of metabotropic glutamate receptors (mGluR5), which leads to an increase in intracellular calcium and causes synapse deterioration. Since mGluR5 is widely distrib

Craig Atwood on Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease.

COMMENT The Alzheimer's Disease and Cancer Relationship These results raise the question of whether amyloid-β peptides might be useful anti-cancer agents. It also adds further support to the idea that amyloid-β has differential effects on pluripotent/totipot

Paul Coleman on Postmortem interval effect on RNA and gene expression in human brain tissue.

COMMENT This paper presents useful information on the effects of postmortem delay on yield and quality of RNA extracted from human brain. The generalization is that long postmortem delay reduces the yield and quality of extracted RNA. 0 Paul_Coleman

The Plot Thickens: The Complicated Relationship of Tau and Aβ

RESEARCH NEWS 2010-09-12 Research News For years, the two classic proteins of Alzheimer disease—Aβ and tau—seemed to move in separate orbits. Gradually, researchers are finding these proteins revolve more closely around each other than they had thought, as two new papers highligh

New γ-Secretase Modulators Reduce Aβ42, Avoid Notch

RESEARCH NEWS 2010-09-12 Research News Despite recent setbacks on the clinical front (see ARF related news story), the hunt for small molecules that can cleanly tweak γ-secretase to slow Alzheimer disease seems to be alive and well. In the September 9 Neuron, researchers led by S