PAPER Peixoto RT, Kunz PA, Kwon H, Mabb AM, Sabatini BL, Philpot BD, Ehlers MD
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330026 RESULTS
PAPER Gupta N, Henry RG, Strober J, Kang SM, Lim DA, Bucci M, Caverzasi E, Gaetano L, Mandelli ML, Ryan T, Perry R, Farrell J, Jeremy RJ, Ulman M, Huhn SL, Barkovich AJ, Rowitch DH
Neural stem cell engraftment and myelination in the human brain.
Sci Transl Med. 2012 Oct 10;4(155):155ra137. PubMed: 23052294PAPER Uchida N, Chen K, Dohse M, Hansen KD, Dean J, Buser JR, Riddle A, Beardsley DJ, Wan Y, Gong X, Nguyen T, Cummings BJ, Anderson AJ, Tamaki SJ, Tsukamoto A, Weissman IL, Matsumoto SG, Sherman LS, Kroenke CD, Back SA
Human neural stem cells induce functional myelination in mice with severe dysmyelination.
Sci Transl Med. 2012 Oct 10;4(155):155ra136. PubMed: 23052293Cheryl Wellington on ApoE4 Promotes Aβ Oligomerization
COMMENT Carriers of the detrimental ApoE4 genotype have long been hypothesized to have slower Aβ catabolism, leading to earlier onset and more amyloid burden than non-ApoE4 carriers. Critical questions involve defining the mechanisms by which ApoE4 leads to slugg
Tytus Murphy
King's College LondonLondon
New Strategies for Early Diagnosis of AD
CONFERENCE COVERAGE 2012-10-26 Conference Coverage “Earlier” seems to be the new mantra in Alzheimer’s research. With biomarker data indicating that amyloid pathology begins up to 20 years before symptoms appear, many researchers now believe that treatment should start in the preclinic
Thousands of Whole Genomes to Be Mined for New Clues to AD
RESEARCH NEWS 2012-10-26 Research News With its ever-dropping price tag, whole-genome sequencing is taking off in Alzheimer's research. Several new collaborative projects aim to use this technology to more deeply understand Alzheimer's disease and find genetic clues to
ApoE4 Promotes Aβ Oligomerization
RESEARCH NEWS 2012-10-26 Research News How does apolipoprotein E (ApoE) boost risk for late-onset Alzheimer’s disease (LOAD)? While prior work suggests it accelerates amyloid-β deposition, a study in the October 24 Journal of Neuroscience examines how ApoE, the top LOAD risk gene
PAPER Ghosh A, Kanthasamy A, Joseph J, Anantharam V, Srivastava P, Dranka BP, Kalyanaraman B, Kanthasamy AG
Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease.
J Neuroinflammation. 2012;9:241. PubMed: 23092448PAPER Gonzalez-Reyes LE, Verbitsky M, Blesa J, Jackson-Lewis V, Paredes D, Tillack K, Phani S, Kramer ER, Przedborski S, Kottmann AH
Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit.
Neuron. 2012 Jul 26;75(2):306-19. PubMed: 22841315PAPER Cong WN, Cai H, Wang R, Daimon CM, Maudsley S, Raber K, Canneva F, von Hörsten S, Martin B
Altered hypothalamic protein expression in a rat model of Huntington's disease.
PLoS One. 2012;7(10):e47240. PubMed: 23094041PAPER Farb NA, Grady CL, Strother S, Tang-Wai DF, Masellis M, Black S, Freedman M, Pollock BG, Campbell KL, Hasher L, Chow TW
Abnormal network connectivity in frontotemporal dementia: Evidence for prefrontal isolation.
Cortex. 2012 Sep 24; PubMed: 23092697PAPER Chico LK, Watterson DM
The 6th drug discovery for neurodegeneration conference: an intensive course on translating research into drugs.
Expert Opin Drug Discov. 2012 Dec;7(12):1225-8. PubMed: 23092534PAPER Panchal M, El Abida B, Lazar N, Fahy C, Dubost L, Friguet B, Rholam M
Clearance of genetic variants of amyloid ß peptide by neuronal and non-neuronal cells.
Protein Pept Lett. 2012 Oct 15; PubMed: 23092134PAPER Carratu MR, Marasco C, Signorile A, Scuderi C, Steardo L
Are retinoids a promise for Alzheimer's disease management?
Curr Med Chem. 2012 Dec 1;19(36):6119-25. PubMed: 23092137Current Filters
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