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Neuroimaging of dementia in 2013: what radiologists need to know.

Eur Radiol. 2013 Jul 10; PubMed: 23839168

PAPER Pooler AM, Polydoro M, Wegmann SK, Pitstick R, Kay KR, Sanchez L, Carlson GA, Gomez-Isla T, Albers MW, Spires-Jones TL, Hyman BT

Tau- amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology.

J Comp Neurol. 2013 Jul 10; PubMed: 23839581

PAPER Ana S, Eelinor C, Van Hoesen GW, Lennart H, Ahmed S, Frithjof K, Mastrianni J

In vivo parahippocampal white matter pathology as a biomarker of disease progression to alzheimer disease.

J Comp Neurol. 2013 Jul 10; PubMed: 23839862

PAPER Mura T, Proust-Lima C, Jacqmin-Gadda H, Akbaraly TN, Touchon J, Dubois B, Berr C

Measuring cognitive change in subjects with prodromal Alzheimer's disease.

J Neurol Neurosurg Psychiatry. 2013 Jul 9; PubMed: 23840054

PAPER García-Escudero V, Martín-Maestro P, Perry G, Avila J

Deconstructing mitochondrial dysfunction in Alzheimer disease.

Oxid Med Cell Longev. 2013;2013:162152. PubMed: 23840916

PAPER Kumfor F, Irish M, Hodges JR, Piguet O

The orbitofrontal cortex is involved in emotional enhancement of memory: evidence from the dementias.

Brain. 2013 Oct;136(Pt 10):2992-3003. PubMed: 23838694

PAPER Fujimaki N, Kitamura F, Takeuchi H

Pro-Oxidant Copper-Binding Mode of the Apo Form of ALS-Linked SOD1 Mutant H43R Denatured at Physiological Temperature.

Biochemistry. 2013 Jul 22; PubMed: 23837654

PAPER Moujalled D, James JL, Parker SJ, Lidgerwood GE, Duncan C, Meyerowitz J, Nonaka T, Hasegawa M, Kanninen KM, Grubman A, Liddell JR, Crouch PJ, White AR

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.

PLoS One. 2013;8(6):e67433. PubMed: 23840699

PAPER Georgy GS, Nassar NN, Mansour HA, Abdallah DM

Cerebrolysin Ameloriates Cognitive Deficits in Type III Diabetic Rats.

PLoS One. 2013;8(6):e64847. PubMed: 23840309

PAPER Bezprozvanny I

Presenilins and calcium signaling-systems biology to the rescue.

Sci Signal. 2013 Jul 9;6(283):pe24. PubMed: 23838181

Jean Georges

Alzheimer Europe
United States

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Models for event-driven data: longitudinal daily adverse event and dropout.

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PAPER Romanelli MF, Morris JC, Ashkin K, Coben LA

Advanced Alzheimer's disease is a risk factor for late-onset seizures.

Arch Neurol. 1990 Aug;47(8):847-50. PubMed: 2375689

TDP-43

ALZPEDIA In 2006, TAR DNA-binding protein 43 (TDP-43) was identified as the cardinal protein in the most common subtypes of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Together with the 2006 discovery of progranulin, this was a major bre

TREM2

ALZPEDIA Triggering receptor expressed on myeloid cells 2 (TREM2) is a receptor of the innate immune system expressed on microglia, macrophages, dendritic cells, and osteoclasts. TREM2 is a member of the immunoglobulin superfamily. Endogenous ligands of this recep