CONFERENCE COVERAGE 2017-08-17 Conference Coverage At the Alzheimer’s Association International Conference 2017 held in London July 14-20, the relationship between disturbed sleep and AD came into sharper focus. Scientists revealed how sleep disordered breathing boosts the risk for ...
PAPER Jones SG, Riedner BA, Smith RF, Ferrarelli F, Tononi G, Davidson RJ, Benca RM
Regional reductions in sleep electroencephalography power in obstructive sleep apnea: a high-density EEG study.Sleep. 2014 Feb 1;37(2):399-407. PubMed: 24497668
PAPER Young T, Shahar E, Nieto FJ, Redline S, Newman AB, Gottlieb DJ, Walsleben JA, Finn L, Enright P, Samet JM, Sleep Heart Health Study Research Group
Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study.Arch Intern Med. 2002 Apr 22;162(8):893-900. PubMed: 11966340
PAPER Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM23589584
PAPER Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, Hibbert S, Budnik N, Zampedri L, Dickson J, Li Y, Aviles-Olmos I, Warner TT, Limousin P, Lees AJ, Greig NH, Tebbs S, Foltynie T
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.Lancet. 2017 Aug 3; PubMed: 28781108
PAPER Athauda D, Wyse R, Brundin P, Foltynie T28777758
RESEARCH NEWS 2017-08-17 Research News August brought some welcome news for the Parkinson’s community: results from a Phase 2 clinical trial suggested the diabetes drug exenatide halted the worsening of motor problems in people in moderate stages of the disease. As reported in ...
RESEARCH NEWS 2017-08-15 Research News Talk about instant gratification. According to an August 8 paper in Cell Reports, injecting a fragment of the protein klotho markedly improves memory and motor function in mice. Klotho is a protein associated with cognitive function in ...
RESEARCH NEWS 2017-08-15 Research News Genetic forces drive a sizable portion of Alzheimer’s disease, yet only a fraction of cases thus far are explained by known mutations. A handful of recent papers used genomic sequencing to fish out new variants that, while exceedingly rare, ...
PAPER Gitlin LN, Kales HJ, Marx K, Stanislawski B, Lyketsos C
A randomized trial of a web-based platform to help families manage dementia-related behavioral symptoms: The WeCareAdvisor™.Contemp Clin Trials. 2017 Aug 8; PubMed: 28800895
PAPER Bella ED, Tramacere I, Antonini G, Borghero G, Capasso M, Caponnetto C, Chiò A, Corbo M, Eleopra R, Filosto M, Giannini F, Granieri E, Bella V, Lunetta C, Mandrioli J, Mazzini L, Messina S, Monsurrò MR, Mora G, Riva N, Rizzi R, Siciliano G, Silani V, Simone I, Sorarù G, Volanti P, Lauria G
Protein misfolding, amyotrophic lateral sclerosis and guanabenz: protocol for a phase II RCT with futility design (ProMISe trial).BMJ Open. 2017 Aug 11;7(8):e015434. PubMed: 28801400
PAPER Stephan BC, Harrison SL, Keage HA, Babateen A, Robinson L, Siervo M28801790
PAPER Álvarez-Arellano L, Pedraza-Escalona M, Blanco-Ayala T, Camacho-Concha N, Cortés-Mendoza J, Pérez-Martínez L, Pedraza-Alva G
Autophagy impairment by caspase-1-dependent inflammation mediates memory loss in response to β-Amyloid peptide accumulation.J Neurosci Res. 2017 Aug 12; PubMed: 28801921
PAPER Ulland TK, Song WM, Huang SC, Ulrich JD, Sergushichev A, Beatty WL, Loboda AA, Zhou Y, Cairns NJ, Kambal A, Loginicheva E, Gilfillan S, Cella M, Virgin HW, Unanue ER, Wang Y, Artyomov MN, Holtzman DM, Colonna M28802038
PAPER Datta A, Chai YL, Tan JM, Lee JH, Francis PT, Chen CP, Sze SK, Lai MK
An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias.Mol Brain. 2017 Aug 11;10(1):36. PubMed: 28800743
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