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TMEM106B and Progranulin Duke It Out at the Lysosome

RESEARCH NEWS 2017-07-20 Research News Mutations in the progranulin gene cause a good many cases of frontotemporal dementia (FTD), the most common form of early onset dementia. But not everyone with a progranulin mutation gets FTD—some lucky souls are protected by variants in a ...

Alzheimer’s Proteomics Treasure Trove?

CONFERENCE COVERAGE 2017-07-20 Conference Coverage The Alzheimer’s disease proteome has remained mostly a mystery. At the EMBO/EMBL Symposium on Mechanisms of Neurodegeneration, held June 14-17 in Heidelberg, Germany, Nick Seyfried described one of the first major attempts to chart ...

PAPER Saugstad JA, Lusardi TA, Van Keuren-Jensen KR, Phillips JI, Lind B, Harrington CA, McFarland TJ, Courtright AL, Reiman RA, Yeri AS, Kalani MY, Adelson PD, Arango J, Nolan JP, Duggan E, Messer K, Akers JC, Galasko DR, Quinn JF, Carter BS, Hochberg FH

Analysis of extracellular RNA in cerebrospinal fluid.

J Extracell Vesicles. 2017;6(1):1317577. Epub 2017 May 24 PubMed: 28717417

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