PAPER Cornille E, Abou-Hamdan M, Khrestchatisky M, Nieoullon A, de Reggi M, Gharib B
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PAPER Bonnefont-Rousselot D, Collin F
Melatonin: action as antioxidant and potential applications in human disease and aging.
Toxicology. 2010 Nov 28;278(1):55-67. PubMed: 20417677PAPER Morris LG, Veeriah S, Chan TA
Genetic determinants at the interface of cancer and neurodegenerative disease.
Oncogene. 2010 Jun 17;29(24):3453-64. PubMed: 20418918PAPER Soriano SG, Liu Q, Li J, Liu JR, Han XH, Kanter JL, Bajic D, Ibla JC
Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain.
Anesthesiology. 2010 May;112(5):1155-63. PubMed: 20418696PAPER Wines-Samuelson M, Schulte EC, Smith MJ, Aoki C, Liu X, Kelleher RJ 3rd, Shen J
Characterization of age-dependent and progressive cortical neuronal degeneration in presenilin conditional mutant mice.
PLoS One. 2010 Apr 15;5(4):e10195. PubMed: 20419112PAPER Misiak M, Beyer C, Arnold S
Gender-specific role of mitochondria in the vulnerability of 6-hydroxydopamine-treated mesencephalic neurons.
Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1178-88. PubMed: 20416276PAPER Ghebremedhin E, Rosenberger A, Rüb U, Vuksic M, Berhe T, Bickeböller H, De Vos RA, Thal DR, Deller T
Inverse relationship between cerebrovascular lesions and severity of lewy body pathology in patients with lewy body diseases.
J Neuropathol Exp Neurol. 2010 May;69(5):442-8. PubMed: 20418782PAPER Rosen RF, Tomidokoro Y, Ghiso JA, Walker LC
SDS-PAGE/immunoblot detection of Abeta multimers in human cortical tissue homogenates using antigen-epitope retrieval.
J Vis Exp. 2010;(38) PubMed: 20418805PAPER Portelius E, Bogdanovic N, Gustavsson MK, Volkmann I, Brinkmalm G, Zetterberg H, Winblad B, Blennow K
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease.
Acta Neuropathol. 2010 Aug;120(2):185-93. PubMed: 20419305PAPER Di X, Yan J, Zhao Y, Zhang J, Shi Z, Chang Y, Zhao B
L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway.
Neuroscience. 2010 Jul 14;168(3):778-86. PubMed: 20416364PAPER Redondo RL, Okuno H, Spooner PA, Frenguelli BG, Bito H, Morris RG
Synaptic tagging and capture: differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation.
J Neurosci. 2010 Apr 7;30(14):4981-9. PubMed: 20371818PAPER Lu G, Zhou QX, Kang S, Li QL, Zhao LC, Chen JD, Sun JF, Cao J, Wang YJ, Chen J, Chen XY, Zhong DF, Chi ZQ, Xu L, Liu JG
Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumulation of extracellular adenosine acting on adenosine A1 receptors.
J Neurosci. 2010 Apr 7;30(14):5058-70. PubMed: 20371826PAPER Norris AJ, Nerbonne JM
Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.
J Neurosci. 2010 Apr 7;30(14):5092-101. PubMed: 20371829Jun Tan on EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.
COMMENT Therapeutics that target soluble oligomeric forms of Aβ and associated neurotoxicity have become a primary focus in recent years. In this issue of PNAS, Erich Wanker and colleagues show that EGCG, the main polyphenolic constituent of green tea, reduces ce
Pamela Keenan
Cronos CCSLambertville, United States
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