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PAPER Simpkins JW, Wood BE, Balin BJ
Alzheimer disease: the crisis is upon us.
J Am Osteopath Assoc. 2010 Sep;110(9 Suppl 8):Sii-2. PubMed: 20926744PAPER Spies PE, Verbeek MM, Olde Rikkert MG, Claassen JA
Cerebrospinal fluid biomarkers in Alzheimer's disease: are the hypotheses more dynamic than the biomarkers?
J Am Geriatr Soc. 2010 Aug;58(8):1619-20. PubMed: 20942893PAPER Giovacchini G, Squitieri F, Esmaeilzadeh M, Milano A, Mansi L, Ciarmiello A
PET translates neurophysiology into images: A review to stimulate a network between neuroimaging and basic research.
J Cell Physiol. 2011 Apr;226(4):948-61. PubMed: 20945377PAPER Valenzuela R, Barroso-Chinea P, Villar-Cheda B, Joglar B, Muñoz A, Lanciego JL, Labandeira-Garcia JL
Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death.
J Neuropathol Exp Neurol. 2010 Nov;69(11):1130-42. PubMed: 20940627PAPER Chen HJ, Anagnostou G, Chai A, Withers J, Morris A, Adhikaree J, Pennetta G, de Belleroche JS
Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis.
J Biol Chem. 2010 Dec 17;285(51):40266-81. PubMed: 20940299PAPER Cartelli D, Ronchi C, Maggioni MG, Rodighiero S, Giavini E, Cappelletti G
Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration.
J Neurochem. 2010 Oct;115(1):247-58. PubMed: 20649848PAPER Saito M, Chakraborty G, Hegde M, Ohsie J, Paik SM, Vadasz C
Involvement of ceramide in ethanol-induced apoptotic neurodegeneration in the neonatal mouse brain.
J Neurochem. 2010 Oct;115(1):168-77. PubMed: 20663015PAPER del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J
Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease.
J Neurochem. 2010 Oct;115(1):153-67. PubMed: 20663016PAPER Siddique MM, Tan EK
Neurochemistry changes associated with mutations in familial Parkinson's disease.
Curr Med Chem. 2010;17(35):4378-91. PubMed: 20939808PAPER Choi DK, Koppula S, Choi M, Suk K
Recent developments in the inhibitors of neuroinflammation and neurodegeneration: inflammatory oxidative enzymes as a drug target.
Expert Opin Ther Pat. 2010 Nov;20(11):1531-46. PubMed: 20939683PAPER Wimo A, Jonsson L, Zbrozek A
The Resource Utilization in Dementia (RUD) instrument is valid for assessing informal care time in community-living patients with dementia.
J Nutr Health Aging. 2010 Oct;14(8):685-90. PubMed: 20922346PAPER Colcombe SJ, Erickson KI, Raz N, Webb AG, Cohen NJ, McAuley E, Kramer AF
Aerobic fitness reduces brain tissue loss in aging humans.
J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):176-80. PubMed: 12586857PAPER Erickson KI, Raji CA, Lopez OL, Becker JT, Rosano C, Newman AB, Gach HM, Thompson PM, Ho AJ, Kuller LH
Physical activity predicts gray matter volume in late adulthood: the Cardiovascular Health Study.
Neurology. 2010 Oct 19;75(16):1415-22. PubMed: 20944075Cristian Lasagna-Reeves on Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.
COMMENT It is time to say that the large, easy-to-detect plaques are outdated. An emerging body of evidence suggests that oligomers are the important toxic entities in Alzheimer disease. The work of Sylvain Lesne and Karen Ashe elegantly demonstrated this in an a
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