PAPER Rao-Ruiz P, Rotaru DC, van der Loo RJ, Mansvelder HD, Stiedl O, Smit AB, Spijker S

Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of contextual fear.

Nat Neurosci. 2011 Oct;14(10):1302-8. PubMed: 21909089

PAPER Carew JD, Nair G, Andersen PM, Wuu J, Gronka S, Hu X, Benatar M

Presymptomatic spinal cord neurometabolic findings in SOD1-positive people at risk for familial ALS.

Neurology. 2011 Oct 4;77(14):1370-5. PubMed: 21940617

PAPER Pappatà S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P

Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism.

Neurology. 2011 Oct 4;77(14):1357-62. PubMed: 21940621

PAPER Caro A, Tarabova B, Rojo-Ruiz J, Lacinova L

Nimodipine inhibits AP firing in cultured hippocampal neurons predominantly due to block of voltage-dependent potassium channels.

Gen Physiol Biophys. 2011;30 Spec No:S44-53. PubMed: 21869451

PAPER Pavlikova M, Kovalska M, Tatarkova Z, Sivonova-Kmetova M, Kaplan P, Lehotsky J

Response of secretory pathways Ca(2+) ATPase gene expression to hyperhomocysteinemia and/or ischemic preconditioning in rat cerebral cortex and hippocampus.

Gen Physiol Biophys. 2011;30 Spec No:S61-9. PubMed: 21869453

PAPER Fecto F, Yan J, Vemula SP, Liu E, Yang Y, Chen W, Zheng JG, Shi Y, Siddique N, Arrat H, Donkervoort S, Ajroud-Driss S, Sufit RL, Heller SL, Deng HX, Siddique T

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.

Arch Neurol. 2011 Nov;68(11):1440-6. PubMed: 22084127

PAPER Tan EK

Rare and common LRRK2 exonic variants in Parkinson's disease.

Lancet Neurol. 2011 Oct;10(10):869-70. PubMed: 21885346

PAPER Ross OA, Soto-Ortolaza AI, Heckman MG, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice A, Brighina L, Van Broeckhoven C, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A, Ferrarese C, Ferraris A, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick GD, Mutez E, Nilsson C, Opala G, Park SS, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, van de Loo S, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Farrer MJ, Genetic Epidemiology Of Parkinson's Disease (GEO-PD) Consortium

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

Lancet Neurol. 2011 Oct;10(10):898-908. Epub 2011 Aug 30 PubMed: 21885347

PAPER Di Castro MA, Chuquet J, Liaudet N, Bhaukaurally K, Santello M, Bouvier D, Tiret P, Volterra A

Local Ca2+ detection and modulation of synaptic release by astrocytes.

Nat Neurosci. 2011 Oct;14(10):1276-84. PubMed: 21909085

PAPER Prinz M, Priller J, Sisodia SS, Ransohoff RM

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration.

Nat Neurosci. 2011 Oct;14(10):1227-35. PubMed: 21952260

PAPER Guo JU, Ma DK, Mo H, Ball MP, Jang MH, Bonaguidi MA, Balazer JA, Eaves HL, Xie B, Ford E, Zhang K, Ming GL, Gao Y, Song H

Neuronal activity modifies the DNA methylation landscape in the adult brain.

Nat Neurosci. 2011 Oct;14(10):1345-51. PubMed: 21874013

Evolution of AD Trials

WEBINAR 2011-11-17 In a sign that researchers are grappling with therapy development, the 4th International Conference on Clinical Trials on Alzheimer's Disease was filled beyond the capacity of its venue, drawing 522 researchers from around the globe. Held 3-5 Novembe

PAPER Farimani MM, Sarvestani NN, Ansari N, Khodagholi F

Calycopterin promotes survival and outgrowth of neuron-like PC12 cells by attenuation of oxidative- and ER-stress-induced apoptosis along with inflammatory response.

Chem Res Toxicol. 2011 Dec 19;24(12):2280-92. PubMed: 22081883

PAPER Chadwick L, Gentle L, Strachan J, Layfield R

Unchained maladie- a reassessment of the role of Ubb(+1)-capped polyubiquitin chains in Alzheimer's disease.

Neuropathol Appl Neurobiol. 2011 Nov 14; PubMed: 22082077

PAPER Babizhayev MA, Deyev AI, Yegorov YE

Olfactory dysfunction and cognitive impairment in age-related neurodegeneration: prevalence related to patient selection, diagnostic criteria and therapeutic treatment of aged clients receiving clinical neurology and community-based care.

Curr Clin Pharmacol. 2011 Nov 1;6(4):236-59. PubMed: 22082323