PAPER Khalid S, Paul S

Identifying a C-terminal ATP binding sites-based novel Hsp90-Inhibitor in silico: a plausible therapeutic approach in Alzheimer's disease.

Med Hypotheses. 2014 Jul;83(1):39-46. Epub 2014 Apr 13 PubMed: 24785461

PAPER O'Malley TT, Oktaviani NA, Zhang D, Lomakin A, O'Nuallain B, Linse S, Benedek GB, Rowan MJ, Mulder FA, Walsh DM

Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies.

Biochem J. 2014 Aug 1;461(3):413-26. PubMed: 24785004

PAPER Veloso AJ, Chow AM, Ganesh HV, Li N, Dhar D, Wu DC, Mikhaylichenko S, Brown IR, Kerman K

Electrochemical immunosensors for effective evaluation of amyloid-beta modulators on oligomeric and fibrillar aggregation processes.

Anal Chem. 2014 May 20;86(10):4901-9. Epub 2014 Apr 30 PubMed: 24784791

PAPER Isobe K, Cheng Z, Nishio N, Suganya T, Tanaka Y, Ito S

iPSCs, aging and age-related diseases.

N Biotechnol. 2014 Sep 25;31(5):411-21. Epub 2014 Apr 29 PubMed: 24784583

PAPER Mourtas S, Lazar AN, Markoutsa E, Duyckaerts C, Antimisiaris SG

Multifunctional nanoliposomes with curcumin-lipid derivative and brain targeting functionality with potential applications for Alzheimer disease.

Eur J Med Chem. 2014 Jun 10;80:175-83. Epub 2014 Apr 18 PubMed: 24780594

PAPER Volgraf M, Chan L, Huestis MP, Purkey HE, Burkard M, Geck Do M, Harris J, Hunt KW, Liu X, Lyssikatos JP, Rana S, Thomas AA, Vigers GP, Siu M

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.

Bioorg Med Chem Lett. 2014 Jun 1;24(11):2477-80. Epub 2014 Apr 13 PubMed: 24780121

PAPER Calì T, Ottolini D, Brini M

Calcium signaling in Parkinson's disease.

Cell Tissue Res. 2014 May 1; PubMed: 24781149

PAPER Maillard P, Fletcher E, Lockhart SN, Roach AE, Reed B, Mungas D, DeCarli C, Carmichael OT

White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain.

Stroke. 2014 Jun;45(6):1721-6. Epub 2014 Apr 29 PubMed: 24781079

PAPER Schaefer A, Quinque EM, Kipping JA, Arélin K, Roggenhofer E, Frisch S, Villringer A, Mueller K, Schroeter ML

Early small vessel disease affects frontoparietal and cerebellar hubs in close correlation with clinical symptoms-a resting-state fMRI study.

J Cereb Blood Flow Metab. 2014 Jul;34(7):1091-5. Epub 2014 Apr 30 PubMed: 24780899

PAPER Krishnan R, Tsubery H, Proschitsky MY, Asp E, Lulu M, Gilead S, Gartner M, Waltho JP, Davis PJ, Hounslow AM, Kirschner DA, Inouye H, Myszka DG, Wright J, Solomon B, Fisher RA

A bacteriophage capsid protein provides a general amyloid interaction motif (GAIM) that binds and remodels misfolded protein assemblies.

J Mol Biol. 2014 Jun 26;426(13):2500-19. Epub 2014 Apr 22 PubMed: 24768993

PAPER Rekha KR, Selvakumar GP, Inmozhi Sivakamasundari R

Gene expression regulation of Bcl2, Bax and cytochrome-C by geraniol on chronic MPTP/probenecid induced C57BL/6 mice model of Parkinson's disease.

Chem Biol Interact. 2014 Jun 25;217:57-66. Epub 2014 Apr 24 PubMed: 24768735

PAPER Schaffer AE, Eggens VR, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu XD, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG

CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.

Cell. 2014 Apr 24;157(3):651-63. PubMed: 24766810

PAPER Holmes WM, Klaips CL, Serio TR

Defining the limits: Protein aggregation and toxicity in vivo.

Crit Rev Biochem Mol Biol. 2014 Apr 28; PubMed: 24766537

PAPER Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH

The Spectrum of Neuro-behavioral Sequelae Following Repetitive Mild Traumatic Brain Injury: A Novel Mouse Model of Chronic Traumatic Encephalopathy (CTE).

J Neurotrauma. 2014 Apr 25; PubMed: 24766454

PAPER Wu CK, Yang YH, Lin TT, Tsai CT, Hwang JJ, Lin JL, Chen PC, Chiang FT, Lin LY

Statin use reduces the risk of dementia in elderly patients: a nationwide data survey and propensity analysis.

J Intern Med. 2014 Apr 25; PubMed: 24766342