PAPER Sörgjerd KM, Zako T, Sakono M, Stirling PC, Leroux MR, Saito T, Nilsson P, Sekimoto M, Saido TC, Maeda M
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PAPER Costanzo M, Zurzolo C
The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration.
Biochem J. 2013 May 15;452(1):1-17. PubMed: 23614720PAPER De Caluwé J, Dupont G
The progression towards Alzheimer's disease described as a bistable switch arising from the positive loop between amyloids and Ca(2+).
J Theor Biol. 2013 Aug 21;331:12-8. PubMed: 23614875PAPER Lim D, Iyer A, Ronco V, Grolla AA, Canonico PL, Aronica E, Genazzani AA
Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB.
Glia. 2013 Jul;61(7):1134-45. PubMed: 23616440PAPER Liu Q, Xie X, Lukas RJ, St John PA, Wu J
A novel nicotinic mechanism underlies β-amyloid-induced neuronal hyperexcitation.
J Neurosci. 2013 Apr 24;33(17):7253-63. PubMed: 23616534PAPER Johnson AA, Sarthi J, Pirooznia SK, Reube W, Elefant F
Increasing Tip60 HAT levels rescues axonal transport defects and associated behavioral phenotypes in a Drosophila Alzheimer's disease model.
J Neurosci. 2013 Apr 24;33(17):7535-47. PubMed: 23616558PAPER Crump CJ, Johnson DS, Li YM
Development and Mechanism of γ-Secretase Modulators for Alzheimer's Disease.
Biochemistry. 2013 May 2; PubMed: 23614767PAPER Dorsey ER, George BP, Leff B, Willis AW
The coming crisis: obtaining care for the growing burden of neurodegenerative conditions.
Neurology. 2013 May 21;80(21):1989-96. PubMed: 23616157PAPER Pause BM, Zlomuzica A, Kinugawa K, Mariani J, Pietrowsky R, Dere E
Perspectives on episodic-like and episodic memory.
Front Behav Neurosci. 2013;7:33. PubMed: 23616754Mikko Hiltunen on Does Progranulin Play Both Sides in AD and FTD?
COMMENT Perry et al. have identified two patients with Alzheimer’s disease (AD) pathology who also have a mutation in the progranulin (GRN) gene. This is an extremely important finding, considering that the GRN mutations are known to cause the autosomal-dominant
Rita Guerreiro on Does Progranulin Play Both Sides in AD and FTD?
COMMENT These are very interesting data, adding to the many cases of potential pleiotropy that we are starting to see more often by applying next-generation sequencing to the study of neurodegenerative diseases. Before the availability of these technologies, sequ
PAPER Faulkner JR, Herrmann JE, Woo MJ, Tansey KE, Doan NB, Sofroniew MV
Reactive astrocytes protect tissue and preserve function after spinal cord injury.
J Neurosci. 2004 Mar 3;24(9):2143-55. PubMed: 14999065PAPER Adams JC, Lawler J
The thrombospondins.
Cold Spring Harb Perspect Biol. 2011 Oct;3(10):a009712. PubMed: 21875984PAPER Eroglu C
The role of astrocyte-secreted matricellular proteins in central nervous system development and function.
J Cell Commun Signal. 2009 Dec;3(3-4):167-76. PubMed: 19904629PAPER Eroglu C, Allen NJ, Susman MW, O'Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM, Lawler J, Dolmetsch R, Garcia KC, Smith SJ, Luo ZD, Rosenthal A, Mosher DF, Barres BA
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.
Cell. 2009 Oct 16;139(2):380-92. PubMed: 19818485Current Filters
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