PAPER Nunes AF, Amaral JD, Lo AC, Fonseca MB, Viana RJ, Callaerts-Vegh Z, D'Hooge R, Rodrigues CM

TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice.

Mol Neurobiol. 2012 Mar 23; PubMed: 22438081

PAPER Brewer GJ

Copper excess, zinc deficiency, and cognition loss in Alzheimer's disease.

Biofactors. 2012 Mar-Apr;38(2):107-13. PubMed: 22438177

PAPER Palmiero M, Di Giacomo D, Passafiume D

Creativity and dementia: a review.

Cogn Process. 2012 Mar 22; PubMed: 22438178

PAPER Palm R, Ayala-Fontanez N, Garcia Y, Lee HG, Smith MA, Casadesus G

Neuroendocrinology-based therapy for Alzheimer's disease.

Biofactors. 2012 Mar-Apr;38(2):123-32. PubMed: 22438197

PAPER Lee JA

Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival?

Exp Neurobiol. 2012 Mar;21(1):1-8. PubMed: 22438673

PAPER Beach TG, Monsell SE, Phillips LE, Kukull W

Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010.

J Neuropathol Exp Neurol. 2012 Apr;71(4):266-73. PubMed: 22437338

PAPER Wray DW, Nishiyama SK, Monnet A, Wary C, Duteil SS, Carlier PG, Richardson RS

Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1870-5. PubMed: 19767527

Marina Dauar

McGill University
Montreal, Canada

Magdalena Kiprowska

Hunter College
United States

Antioxidants No Help for Alzheimer’s, Biomarker Trial Says

RESEARCH NEWS 2012-03-23 Research News The stuff touted to confer anti-aging properties on foods from blueberries to dark chocolate does no good for people with Alzheimer’s disease—and might even make them worse, according to new research. In the March 19 Archives of Neurology on

Keystone: Symposium Emphasizes Key Aspects of ApoE Biology

CONFERENCE COVERAGE 2012-03-23 Conference Coverage Why has it been such a challenge to pinpoint the exact role in pathology of apolipoprotein E, which surpasses all other genetic risk factors for late onset Alzheimer’s disease? In short, because ApoE does so many things. It transports

PAPER Gorbatyuk MS, Shabashvili A, Chen W, Meyers C, Sullivan LF, Salganik M, Lin JH, Lewin AS, Muzyczka N, Gorbatyuk OS

Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease.

Mol Ther. 2012 Mar 20; PubMed: 22434142

PAPER Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.

J Biol Chem. 2012 May 4;287(19):16017-28. PubMed: 22433867

PAPER Jayaraman M, Mishra R, Kodali R, Thakur AK, Koharudin LM, Gronenborn AM, Wetzel R

Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties.

Biochemistry. 2012 Apr 3;51(13):2706-16. PubMed: 22432740

PAPER Luchsinger JA

Type 2 diabetes and cognitive impairment: linking mechanisms.

J Alzheimers Dis. 2012;30 Suppl 2:S185-98. PubMed: 22433668