Krishnapriya Loganathan

Karolinska Institutet, RIKEN Brain Science Institute
Uppsala, Sweden

Studies Challenge Model of NMDA Receptor Function

RESEARCH NEWS 2013-03-01 Research News Glutamate receptors at the postsynaptic membrane play important roles in neural plasticity. It is widely accepted that they either strengthen or weaken neurotransmission by allowing an influx of positively charged ions into the cell. But hol

Does New Amyloid Protein Lend Tau a Hand?

CONFERENCE COVERAGE 2013-03-01 Conference Coverage The tangled protein tau does not stand alone in aggregates. In people with Alzheimer’s and AD model mice, tau appears to have a partner in EF Hand 2 (EFhd2), according to work presented by the laboratory of Irving Vega, of the Universi

Spinal Fluid Flush: Visualizing the Brain Drain With MRI

RESEARCH NEWS 2013-03-01 Research News In August 2012, researchers uncovered a lymph-like drainage system in the brain that relies on glial cells. Now, some of the same authors report in the February 22 Journal of Clinical Investigation that they can visualize this "glymphat

Inducible APP Mice—Cognition Restored in Advanced Amyloidosis?

RESEARCH NEWS 2013-03-01 Research News Shutting off transgenic Aβ production in middle-aged mice whose brains are jam-packed with amyloid pathology was able to rescue some aspects of cognition, according to a study in the February 27 Journal of Neuroscience. In this first publica

PAPER Wang Y, Wang X, Li R, Yang ZF, Wang YZ, Gong XL, Wang XM

A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons.

CNS Neurosci Ther. 2013 Mar;19(3):183-90. PubMed: 23441691

PAPER

Parkinson disease: Transcription factor Nurr1 maintains dopaminergic neurons.

Folia Neuropathol. 2012;50(4):322-9. PubMed: 23443844

PAPER Lee K, Kim Y, Lee SJ, Qiang Y, Lee D, Lee HW, Kim H, Je HS, Südhof TC, Ko J

MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):336-41. Epub 2012 Dec 17 PubMed: 23248271

PAPER Liu G, Wang P, Li X, Li Y, Xu S, Uéda K, Chan P, Yu S

Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons.

J Neural Transm. 2013 Feb 27; PubMed: 23443897

PAPER Yao J, Gao X, Sun W, Yao T, Shi S, Ji L

Molecular hairpin: a possible model for inhibition of tau aggregation by tannic acid.

Biochemistry. 2013 Mar 19;52(11):1893-902. PubMed: 23442089

PAPER Anstey KJ, Bahar-Fuchs A, Herath P, Rebok GW, Cherbuin N

A 12-week multidomain intervention versus active control to reduce risk of Alzheimer's disease: study protocol for a randomized controlled trial.

Trials. 2013;14:60. PubMed: 23442574

PAPER Johnson RD, Schauerte JA, Chang CC, Wisser KC, Althaus JC, Carruthers CJ, Sutton MA, Steel DG, Gafni A

Single-molecule imaging reveals aβ42:aβ40 ratio-dependent oligomer growth on neuronal processes.

Biophys J. 2013 Feb 19;104(4):894-903. PubMed: 23442968

PAPER von Einem B, Weber P, Wagner M, Malnar M, Kosicek M, Hecimovic S, Arnim CA, Schneckenburger H

Cholesterol-Dependent Energy Transfer between Fluorescent Proteins-Insights into Protein Proximity of APP and BACE1 in Different Membranes in Niemann-Pick Type C Disease Cells.

Int J Mol Sci. 2012;13(12):15801-12. PubMed: 23443094

PAPER Abrahamson EE, Foley LM, Dekosky ST, Kevin Hitchens T, Ho C, Kochanek PM, Ikonomovic MD

Cerebral blood flow changes after brain injury in human amyloid-beta knock-in mice.

J Cereb Blood Flow Metab. 2013 Feb 27; PubMed: 23443172

PAPER Zhang B, Cheng XR, da Silva IS, Hung VW, Veloso AJ, Angnes L, Kerman K

Electroanalysis of the interaction between (-)-epigallocatechin-3-gallate (EGCG) and amyloid-β in the presence of copper.

Metallomics. 2013 Mar;5(3):259-64. PubMed: 23443273