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PSEN1 S290_S319delinsC G> T (ΔE9)

MUTATIONS PSEN1 73673093 GRCh37/hg19 rs63750219  G T g.58304G> T g.74916G> T ΔE9 Δ9 S290C;T291_S319del G> T Intron 8, Exon 9 Complex Non-Coding Coding Point mutation in a splice acceptor site in intron 8 resulting in in-frame skipping of exon 9 and S290C c

PSEN1 S290_S319delinsC G> A (ΔE9)

MUTATIONS PSEN1 73673093 GRCh37/hg19 rs63750219 G A g.58304G> A g.74916G> A ΔE9 Δ9 c.869-1G> A S290C;T291_S319del G> A Intron 8, Exon 9 Complex Non-Coding Coding Point mutation in splice acceptor site in intron 8 resulting in skipping of exon 9 and S290

Early Hormone Therapy Does No Cognitive Harm

RESEARCH NEWS 2013-06-28 Research News Doctors often prescribe hormone therapy to help women cope with symptoms of menopause such as hot flashes and night sweats. However, there are concerns that hormone replacement causes cognitive decline. Now, scientists led by Susan Resnick,

Brain Imaging Suggests Neurotransmitter Imbalance in ALS

RESEARCH NEWS 2013-06-28 Research News While it remains impossible to directly measure neurotransmitters and metabolites in the living human brain, radiologists can come close by using magnetic resonance spectroscopy. MRS uses the same equipment as magnetic resonance imaging but

Microglia Need Scara1 Receptor to Clear Soluble Amyloid

RESEARCH NEWS 2013-06-28 Research News Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance. In a June 25 Nature Communications paper, researchers led by Joseph El Khoury at Massachusetts General

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