PAPER Lehtimäki T, Dastidar P, Jokela H, Koivula T, Lehtinen S, Ehnholm C, Punnonen R

Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype.

J Clin Endocrinol Metab. 2002 Sep;87(9):4147-53. PubMed: 12213863

PAPER Whitmer RA, Quesenberry CP, Zhou J, Yaffe K

Timing of hormone therapy and dementia: The critical window theory revisited.

Ann Neurol. 2010 Nov 12; PubMed: 21077179

PAPER Satoh K, Nigro P, Berk BC

Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A.

Antioxid Redox Signal. 2010 Mar 1;12(5):675-82. PubMed: 19747062

PAPER Jin ZG, Lungu AO, Xie L, Wang M, Wong C, Berk BC

Cyclophilin A is a proinflammatory cytokine that activates endothelial cells.

Arterioscler Thromb Vasc Biol. 2004 Jul;24(7):1186-91. PubMed: 15130913

Strickman Ripps

United States

San Diego: Researchers Rejuvenate Neurons to Bridge Spinal Cord Gaps

CONFERENCE COVERAGE 2010-12-08 Conference Coverage Spinal cord injury creates a rift that has proven extremely difficult to bridge—once the spine is severed or crushed, the neurons on either side remain forever divided. But perhaps there are ways to close the gap, researchers reported

San Diego: The Curious Case of ApoE, Cholesterol, and Cognition

CONFERENCE COVERAGE 2010-12-08 Conference Coverage Cholesterol not only clogs up arteries and leads to heart disease, but it can be bad for your brain as well. Evidence for cholesterol’s role in Alzheimer’s disease has been growing in recent years, and many cardiovascular risk factors

PAPER Hasegawa S, Saito S, Takanashi J, Morokoshi Y, Furukawa T, Saga T, Aoki I

Evaluation of ferritin-overexpressing brain in newly developed transgenic mice.

Magn Reson Imaging. 2011 Feb;29(2):179-84. PubMed: 21129877

PAPER Schenk GJ, Vreugdenhil E, Hubens CJ, Veldhuisen B, de Kloet ER, Oitzl MS

Hippocampal CARP over-expression solidifies consolidation of contextual fear memories.

Physiol Behav. 2011 Mar 1;102(3-4):323-31. PubMed: 21130104

PAPER Benoit CE, Rowe WB, Menard C, Sarret P, Quirion R

Genomic and proteomic strategies to identify novel targets potentially involved in learning and memory.

Trends Pharmacol Sci. 2011 Jan;32(1):43-52. PubMed: 21129790

PAPER Kühnlein P, Jung H, Farkas M, Keskitalo S, Ineichen B, Jelcic I, Petersen J, Semmler A, Weller M, Ludolph AC, Linnebank M

The thermolabile variant of 5,10-methylenetetrahydrofolate reductase is a possible risk factor for amyotrophic lateral sclerosis.

Amyotroph Lateral Scler. 2011 Mar;12(2):136-9. PubMed: 21128869

PAPER Egawa N, Yamamoto K, Inoue H, Hikawa R, Nishi K, Mori K, Takahashi R

The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death.

J Biol Chem. 2011 Mar 11;286(10):7947-57. PubMed: 21131360

PAPER Ayala YM, De Conti L, Avendaño-Vázquez SE, Dhir A, Romano M, D'Ambrogio A, Tollervey J, Ule J, Baralle M, Buratti E, Baralle FE

TDP-43 regulates its mRNA levels through a negative feedback loop.

EMBO J. 2011 Jan 19;30(2):277-88. PubMed: 21131904

PAPER Näsström T, Fagerqvist T, Barbu M, Karlsson M, Nikolajeff F, Kasrayan A, Ekberg M, Lannfelt L, Ingelsson M, Bergström J

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties.

Free Radic Biol Med. 2011 Feb 1;50(3):428-37. PubMed: 21130160

PAPER Gordon PH

Amyotrophic lateral sclerosis: pathophysiology, diagnosis and management.

CNS Drugs. 2011 Jan;25(1):1-15. PubMed: 21128691