AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C3673<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide: 44H M N V Q N G K W D S D P S G T K T C I 63 of human amyloid precursor protein liquid, neat serum, azide, delipidation, defibrination aa s

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C3669<br /> manufacturer: LifeSpan Biosciences immunogen = Synthetic Peptide: 681 G Y E N P T Y K F F E Q M Q N 695 of human amyloid precursor protein frameshift mutant liquid, neat serum, unpurified azide recognizes

AβPP frameshift mutant

ANTIBODY polyclonal manufacturer Cat# LS-C3666<br /> manufacturer: LifeSpan Biosciences immunogen = Synthetic Peptide: 339 R G R T S S K E L A 348 of human amyloid precursor protein frameshift mutant liquid, serum, azide, delipidation, defibrination recogniz

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C20573<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to residues at the N-terminus of human beta-amyloid peptides (KLH) liquid, HEPES, NaCl, BSA, glycerol, affinity purified recognize

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C26943<br /> manufacturer: LifeSpan Biosciences IgG APP, APLP, AICD Autogen Bioclear Rabbit Human A&#946;PP http://alzforum.org/res/com/ant/default.asp?antibodyID=35331

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C20586<br /> manufacturer: LifeSpan Biosciences immunogen = 30aa synthetic peptide derived from the full length (1-43 amino acid) β-amyloid peptide liquid, PBS, azide, affinity purified specific for the 4-5kD human β-

AβPP frameshift mutant

ANTIBODY polyclonal manufacturer Cat# LS-C3656<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to aa339-348 of the C-terminal region of the human Alzheimer's amyloid precursor protein frameshift mutant liquid, unpurified

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C68965<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to a protein sequence derived from N-terminus of human Amyloid Beta liquid, PBS, BSA, azide, affinity purified recognizes human Amy

AβPP

ANTIBODY polyclonal manufacturer Cat# LS-C88784<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide from aa 8-17 of human amyloid beta-protein liquid, PBS, BSA, azide, affinity purified APP IgG APP, APLP, AICD Autogen Bioclear Rabbit Human

Kenneth Van Blarcom

South Natick, United States

Freya Vercauteren

McGill University
Montreal, Canada

Rudolf Bloechl on Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5.

COMMENT The very interesting report by Renner et al. demonstrates Aβ-induced clustering of mGluR5 receptors and suggests that membrane-bound Aβ oligomers interact with mGluR5. Since chemical crosslinking of the receptor and application of Aβ oligomers produce sim

PAPER Popkirov SG, Manahan-Vaughan D

Involvement of the metabotropic glutamate receptor mGluR5 in NMDA receptor-dependent, learning-facilitated long-term depression in CA1 synapses.

Cereb Cortex. 2011 Mar;21(3):501-9. PubMed: 20525770

PAPER Traynor BJ, Nalls M, Lai SL, Gibbs RJ, Schymick JC, Arepalli S, Hernandez D, van der Brug MP, Johnson JO, Dillman A, Cookson M, Moglia C, Calvo A, Restagno G, Mora G, Chiò A

Kinesin-associated protein 3 (KIFAP3) has no effect on survival in a population-based cohort of ALS patients.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12335-8. PubMed: 20566859

PAPER Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C, Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S

DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Nat Cell Biol. 2007 May;9(5):604-11. PubMed: 17435748