PAPER Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimäki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M

Strong association of de novo copy number mutations with autism.

Science. 2007 Apr 20;316(5823):445-9. Epub 2007 Mar 15 PubMed: 17363630

PAPER Vacic V, McCarthy S, Malhotra D, Murray F, Chou HH, Peoples A, Makarov V, Yoon S, Bhandari A, Corominas R, Iakoucheva LM, Krastoshevsky O, Krause V, Larach-Walters V, Welsh DK, Craig D, Kelsoe JR, Gershon ES, Leal SM, Dell Aquila M, Morris DW, Gill M, Corvin A, Insel PA, McClellan J, King MC, Karayiorgou M, Levy DL, DeLisi LE, Sebat J

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

Nature. 2011 Mar 24;471(7339):499-503. Epub 2011 Feb 23 PubMed: 21346763

PAPER Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, Thorne N, Redon R, Bird CP, de Grassi A, Lee C, Tyler-Smith C, Carter N, Scherer SW, Tavaré S, Deloukas P, Hurles ME, Dermitzakis ET

Relative impact of nucleotide and copy number variation on gene expression phenotypes.

Science. 2007 Feb 9;315(5813):848-53. PubMed: 17289997

Meeting Explores Regulatory Requirements for Parkinson's MCI

CONFERENCE COVERAGE 2013-06-27 Conference Coverage Most people with Parkinson's disease eventually develop dementia. Similar to Alzheimer's disease, PD dementia begins with subtle deficits in cognition that progress to symptoms recognizable as mild cognitive impairment (MCI).

Do Copy Number Variations Point to Potential AD Genes?

RESEARCH NEWS 2013-06-27 Research News Scientists hunting for new Alzheimer’s genes usually focus on single nucleotide changes, but a large amount of human genetic variation takes the form of structural rearrangements of DNA, such as deletions and duplications. To look for diseas

PAPER D'amico E, Factor-Litvak P, Santella RM, Mitsumoto H

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis.

Free Radic Biol Med. 2013 Jun 21;65C:509-527. PubMed: 23797033

PAPER Hastings MH, Goedert M

Circadian clocks and neurodegenerative diseases: time to aggregate?

Curr Opin Neurobiol. 2013 Oct;23(5):880-7. PubMed: 23797088

PAPER Cepeda C, Galvan L, Holley SM, Rao SP, André VM, Botelho EP, Chen JY, Watson JB, Deisseroth K, Levine MS

Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models.

J Neurosci. 2013 Apr 24;33(17):7393-406. PubMed: 23616545

PAPER Hwang S, Song S, Hong YK, Choi G, Suh YS, Han SY, Lee M, Park SH, Lee JH, Lee S, Bang SM, Jeong Y, Chung WJ, Lee IS, Jeong G, Chung J, Cho KS

Drosophila DJ-1 decreases neural sensitivity to stress by negatively regulating Daxx-like protein through dFOXO.

PLoS Genet. 2013 Apr;9(4):e1003412. PubMed: 23593018

PAPER Arenaza-Urquijo EM, Landeau B, La Joie R, Mevel K, Mézenge F, Perrotin A, Desgranges B, Bartrés-Faz D, Eustache F, Chételat G

Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders.

Neuroimage. 2013 Jun 21;83C:450-457. PubMed: 23796547

PAPER Foerster BR, Pomper MG, Callaghan BC, Petrou M, Edden RA, Mohamed MA, Welsh RC, Carlos RC, Barker PB, Feldman EL

An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy.

JAMA Neurol. 2013 Aug 1;70(8):1009-16. PubMed: 23797905

PAPER Faiz M, Nagy A

Induced Pluripotent Stem Cells and Disorders of the Nervous System: Progress, Problems, and Prospects.

Neuroscientist. 2013 Jun 24; PubMed: 23797497

PAPER Díaz-Moreno M, Hortigüela R, Gonçalves A, García-Carpio I, Manich G, García-Bermúdez E, Moreno-Estellés M, Eguiluz C, Vilaplana J, Pelegrí C, Vilar M, Mira H

Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice.

Neurobiol Aging. 2013 Nov;34(11):2623-38. PubMed: 23796660

PAPER Joseph-Mathurin N, Dorieux O, Trouche SG, Boutajangout A, Kraska A, Fontès P, Verdier JM, Sigurdsson EM, Mestre-Francés N, Dhenain M

Amyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds.

Neurobiol Aging. 2013 Nov;34(11):2613-22. PubMed: 23796662

PAPER Rogne S, Vangberg T, Eldevik P, Wikran G, Mathiesen EB, Schirmer H

Mild cognitive impairment, risk factors and magnetic resonance volumetry: role of probable Alzheimer's disease in the family.

Dement Geriatr Cogn Disord. 2013;36(1-2):87-98. PubMed: 23797189