A Brain Wrought Without Omega-3

RESEARCH NEWS 2011-02-03 Research News Adapted from a story that originally appeared on the Schizophrenia Research Forum. A diet deficient in omega-3 fatty acids interferes with synaptic function, according to a study published January 30 in Nature Neuroscience. Mice chronically

PAPER Vetri V, Ossato G, Militello V, Digman MA, Leone M, Gratton E

Fluctuation methods to study protein aggregation in live cells: concanavalin A oligomers formation.

Biophys J. 2011 Feb 2;100(3):774-83. PubMed: 21281593

PAPER Uysal N, Tugyan K, Aksu I, Ozbal S, Ozdemir D, Dayi A, Gönenç S, Açikgöz O

Age-related changes in apoptosis in rat hippocampus induced by oxidative stress.

Biotech Histochem. 2012 Feb;87(2):98-104. PubMed: 21281059

PAPER Kronenberg G, Gertz K, Overall RW, Harms C, Klein J, Page MM, Stuart JA, Endres M

Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase.

Exp Neurol. 2011 Apr;228(2):253-8. PubMed: 21281628

PAPER Schoenfeld TJ, Gould E

Stress, stress hormones, and adult neurogenesis.

Exp Neurol. 2011 Jan 31; PubMed: 21281629

PAPER Ryu H, Jeon GS, Cashman NR, Kowall NW, Lee J

Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS.

Lab Invest. 2011 Mar;91(3):342-52. PubMed: 21283077

PAPER Gräff J, Tsai LH

Cognitive enhancement: A molecular memory booster.

Nature. 2011 Jan 27;469(7331):474-5. PubMed: 21270879

PAPER Kim HY, Moon HS, Cao D, Lee J, Kevala K, Jun SB, Lovinger DM, Akbar M, Huang BX

N-Docosahexaenoylethanolamide promotes development of hippocampal neurons.

Biochem J. 2011 Apr 15;435(2):327-36. PubMed: 21281269

PAPER de Chastelaine M, Wang TH, Minton B, Muftuler LT, Rugg MD

The effects of age, memory performance, and callosal integrity on the neural correlates of successful associative encoding.

Cereb Cortex. 2011 Sep;21(9):2166-76. PubMed: 21282317

PAPER Aiken CT, Kaake RM, Wang X, Huang L

Oxidative stress-mediated regulation of proteasome complexes.

Mol Cell Proteomics. 2011 Jan 31; PubMed: 21282529

PAPER Shriner D, Vaughan LK

A unified framework for multi-locus association analysis of both common and rare variants.

BMC Genomics. 2011;12:89. PubMed: 21281506

PAPER Fontainhas AM, Wang M, Liang KJ, Chen S, Mettu P, Damani M, Fariss RN, Li W, Wong WT

Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission.

PLoS One. 2011;6(1):e15973. PubMed: 21283568

Joel Watts

University of Toronto
Toronto, Canada

PAPER Lam AR, Teplow DB, Stanley HE, Urbanc B

Effects of the Arctic (E(22)?G) Mutation on Amyloid ß-Protein Folding: Discrete Molecular Dynamics Study.

J Am Chem Soc. 2011 Mar 2;133(8):2789. PubMed: 21280623

PAPER Feaga HA, Maduka RC, Foster MN, Szalai VA

Affinity of Cu+ for the copper-binding domain of the amyloid-β peptide of Alzheimer's disease.

Inorg Chem. 2011 Mar 7;50(5):1614-8. PubMed: 21280585