Kenneth Kosik on ‘Godfather of Tau’ Skip Binder Dies at 63

COMMENT Irreverent, witty, lively, and always full of kindness and generosity, Skip’s untimely death must give pause to all of us who knew him, and many more who only knew of him. We should build upon his insights as we delve ever more deeply into the diseases th

PAPER Citrome L

A review of the pharmacology, efficacy and tolerability of recently approved and upcoming oral antipsychotics: an evidence-based medicine approach.

CNS Drugs. 2013 Nov;27(11):879-911. PubMed: 24062193

PAPER Giaccone G, Giaccone G, DiFede G, Giovagnoli AR, Tagliavini F

A novel missense mutation in Psen2 gene associated with a clinical phenotype of frontotemporal dementia

Alzheimers Dement. 2008;4(S2):T590

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PS1 polymporphism and a novel PS2 mutation in a patient with late-onset familial Alzheimer's disease

Alzheimers Dement. 2008;4(S2):T585

PAPER Piscopo P, Talarico G, Spadoni O, Malvezzi-Campeggi L, Crestini A, Gasparini M, Vanacore N, Lenzi GL, Pocchiari M, Confaloni A, Bruno G

A novel Italian presenilin 2 mutation (S175Y)

Alzheimers Dement. 2008;4(S2):T595.

PAPER Sorbi S, Tedde A, Nacmias B, Ciantelli M, Caffarra P, Ghidoni E, Bracco L, Piccini C

Novel presenilin 1 and presenilin 2 mutations in early-onset Alzheimer's disease families

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PAPER Clarimón J, Guerreiro R, Lleó A, Guardia C, Blesa F, Gómez-Isla T, Boada M, Bullido MJ, Ferrer I, Martínez-Lage P, Masdeu J, Molina L, Molinuevo JL, Pastor P, Pérez-Tur J, Rey MJ, Sánchez-Valle R, Tàrraga L, Valdivieso F, Singleton A, Hardy J

Genetic screening in a large cohort of early-onset Alzheimer's disease patients from Spain: novel mutations in the amyloid precursor protein and presenilines

Alzheimers Demen. 2008 Jul;4(4 Suppl):T583.

PAPER Hunt L

Memantine improves outlook, cuts healthcare costs in AD

PharmacoEconomics & Outcomes News. 422: 3-4, 2003 Jul 26

FDA Approves a Second Amyloid Imaging Agent

RESEARCH NEWS 2013-11-21 Research News The U.S. Food and Drug Administration on October 25 approved a second amyloid imaging agent. Flutemetamol, renamed Vizamyl, is an F18-labeled ligand developed by GE Healthcare. It joins florbetapir, or Amyvid, developed by Avid Pharmaceutica

‘Godfather of Tau’ Skip Binder Dies at 63

COMMUNITY NEWS 2013-11-21 Community News Colleagues, friends, and family of Lester “Skip” Binder are mourning his sudden passing on November 15, a month shy of his 64th birthday. Known to his fellow researchers as “The Godfather of Tau,” Binder was among the first to recognize tha

PAPER Zu T, Liu Y, Bañez-Coronel M, Reid T, Pletnikova O, Lewis J, Miller TM, Harms MB, Falchook AE, Subramony SH, Ostrow LW, Rothstein JD, Troncoso JC, Ranum LP

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4968-77. Epub 2013 Nov 18 PubMed: 24248382

PAPER Hardy J, Rogaeva E

Motor neuron disease and frontotemporal dementia: sometimes related, sometimes not.

Exp Neurol. 2013 Nov 15; PubMed: 24246281

PAPER Phillipson OT

Management of the aging risk factor for Parkinson's disease.

Neurobiol Aging. 2014 Apr;35(4):847-57. Epub 2013 Oct 10 PubMed: 24246717

PAPER Wu AG, Wong VK, Xu SW, Chan WK, Ng CI, Liu L, Law BY

Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells.

Int J Mol Sci. 2013 Nov 15;14(11):22618-41. PubMed: 24248062

PAPER He Q, Yu W, Wu J, Chen C, Lou Z, Zhang Q, Zhao J, Wang J, Xiao B

Intranasal LPS-mediated Parkinson's model challenges the pathogenesis of nasal cavity and environmental toxins.

PLoS One. 2013;8(11):e78418. Epub 2013 Nov 8 PubMed: 24250796