El Dorado Hills, United States
San Francisco, United States
COMMENT Neuroinflammatory mechanisms have emerged as an important feature and pathogenic event in Alzheimer’s disease. Recently, mutations in TREM2 have been identified as risk factors for the development of the sporadic type of this neurodegenerative disease. In ...
PAPER Jung DY, Lee H, Suk K15953367
PAPER Kim SJ, Li J
Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia.Cell Death Dis. 2013 Jul 11;4:e716. PubMed: 23846218
Full-Time StudentKenosha, United States
RESEARCH NEWS 2015-02-28 Research News When the going gets tough, microglia rely on TREM2 to get going. That was the common conclusion from two papers that investigated the role of the myeloid receptor in mouse models of Alzheimer’s disease and stroke. One study, led by Marco ...
PAPER Cannon JP, O'Driscoll M, Litman GW21800138
PAPER Daws MR, Sullam PM, Niemi EC, Chen TT, Tchao NK, Seaman WE12847223
PAPER Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA
PAPER Wang Y, Cella M, Mallinson K, Ulrich JD, Young KL, Robinette ML, Gilfillan S, Krishnan GM, Sudhakar S, Zinselmeyer BH, Holtzman DM, Cirrito JR, and Colonna M
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