Modification: APP: Transgenic
Disease Relevance: Alzheimer's Disease
Strain Name: B6.Cg-Tg(Prnp-APP)A-2Dbo/J
Genetic Background: C57BL/6
Availability: Jackson Labs: Stock# 006006; Cryopreserved
These mice express human APP driven by the mouse prion protein promoter. Hemizygous mice are viable and fertile, but phenotypic information is not available.
No Available Further Reading