NINDS Human Genetics DNA and Cell Line Repository
The NINDS Human Genetics Resource Center at the Coriell Institute receives blood samples and clinical data and prepares DNA and cell lines for distribution to promote neurogenetics research. The repository includes over 7,000 well-phenotyped DNA samples and cell lines from individuals with epilepsy, Parkinson's disease, stroke, ALS, Tourette syndrome, as well as from neurologically normal controls. Control samples include both population controls and spousal controls.
The Nun Study is a longitudinal study of aging and Alzheimer
Disease sponsored by NIA and housed in the Sanders-Brown Center
on Aging in University of Kentucky. Started in 1986, the study
currently involved 678 American members of the School Sisters
of Notre Dame religious congregation who were 75-103 years
of age. The web site also provide data from the study to researchers.
Developed by the Wisconsin Primate Research Center at the
University of Wisconsin-Madison, the Primate Info Net lists
resources in primatology, federally funded primate research,
an international directory of primatology organizations, a
world directory of primatologists, as well as products and
services for primates.
Directory of regional research centers, academic facilities,
commercial sources and other information on aged non-human
Spongiform Encephalopathy (TSE) Resource Centre
Provides various reagents, including anti-recPrP monoclonal
antibodies to the TSE research community. Maintained by two
researchers from the Crompton Laboratory of the Institute
of Animal Health in UK.
Whole Mouse Catalog
A compendium of web sites with useful information for scientists
using mice in research.
Developed by University of Chicago researchers Neil Smalheiser
and Don Swanson, this novel information retrieval system searches
the biomedical literature for implicit connections, for example
between one biological process and a seemingly unrelated one.
This demonstration site is free for anyone to use. The creators
welcome feedback from users.
Organization, Inc. (Bioinformatics.org)
Founded in 1998 by J.W. Bizzaro, Bioinformatics.Org aims
to facilitate world-wide communications and collaborations
between practicing and neophyte bioinformatic scientists and
technicians. The Organization provides these individuals,
as well as the public at large, free and open access to methods
and materials for and from scientific research, software development,
(Computerized Anatomical Reconstruction and Editing Toolkit)
A software package developed by the Van Essen Laboratory for
visualizing, editing, analyzing, and flattening cortical surface
reconstructions. Also available through the site are data
sets for the human, macaque, and mouse brain atlases. Each
atlas includes surface reconstructions of the left and right
cerebral hemispheres plus the cerebellum, along with high-resolution
structural MRI volumes. The associated experimental data sets
include cortical areas delineated by multiple partitioning
schemes for the human and macaque, plus exemplar fMRI data
sets for human cortex and anatomical connectivity data for
The Computational Neuroscience/Neuroinformatics web site
aims to unravel the complex structure-function relationships
of the brain at all levels from molecule to behavior in an
integrative effort of many scientific disciplines and intends
to foster the development of the field and the growth of an
active community with a focus on Europe.
Cytoscape is an open-source bioinformatics software platform
for visualizing molecular interaction networks and integrating
these interactions with gene expression profiles and other
state data. Cytoscape is under continuous development by scientists
at Institute of Systems Biology, UC San Diego, Whitehead Institute
and The Memorial Sloan-Kettering Cancer Center. Other scientists
and software developers can download the source code at no
A basic how-to site on gene chip technology, run by computational
chemist Leming Shi. Includes extensive directories of links
to other sites with microarray information.
Free, public-domain software for image capturing, processing
The SenseLab Project at the Yale University School of Medicine
is a long term effort to build integrated, multidisciplinary
models of neurons and neural systems. Databases from this
project includes three neuronal databases: Cellular Properties
Database (CellPropDB); NeuronDB; and ModelDB, and three olfactory
Developed at the University of Washington, the goal of the
Telemakus System is to enhance the knowledge discovery process
by developing retrieval, visual and interaction tools to mine
and map research findings from the research literature. The
Caloric Restriction & Nutritional Aspects in Aging database
covers the majority of original research articles in English
with data tables in that field since 1935.
The Biomarkers in Alzheimer's Disease (bioAD KB) database covers studies on the biomarkers apolipoprotein E, amyloidβ, tau and isoprostanes, among others, in Alzheimer’s disease.
Popular free software developed by Max Heiman to map restriction
An open, public platform dedicated to the curation of biological pathways by and for the scientific community.
ADNI Initiatives in Europe
The ADNI platform for data collection was first imported in Europe thanks to the pilot European ADNI, and a number of ADNI-related initiatives have since flourished with different aims, from the development of standard operational procedures for the collection of markers, to the development of infrastructures for the treatment of ADNI data, and the collection of fresh ADNI compatible data. We will here review the most significant ADNI-related initiatives that have been or are being carried out in Europe or led by European scientists.
Molecular Biology Database Collection: 2005 Updates
The Nucleic Acids Research Molecular Biology Database
Collection is a public online resource that lists publicly
accessible databases that are of value to biologists. The
2005 version contains 719 databases from around the world.
The Neuroscience Information Framework
The Neuroscience Information Framework provides access to neuroscience-related public research data and tools. The site includes a registry of neuroscience-relevant resources, an extensive vocabulary for describing resources and their content, and an initial version of a concept-based query system to query across diverse types of resources.
on the Internet
A searchable and browsable index of neuroscience resources
on the Internet.
Review the current entry for Alzheimer disease and add your expertise.