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The National Institute on Aging (NIA), a major research
component of the National Institutes of Health (NIH) and the
Department of Health and Human Services (HHS), is recruiting
postdoctoral fellows with interests in Alzheimer’s disease
(AD) and/or age-associated memory impairment (AAMI) in the
Unit of Clinical and Translational Neuroscience, within the
Laboratory of Behavioral Neuroscience.
This research represents an exciting new initiative
within the NIA intramural research program (IRP) to enhance
our understanding of disease mechanisms underlying risk
factors for AD/AAMI, discover biologically relevant
biomarkers that accurately reflect neuropathology and
identify potential targets for effective disease
modification/intervention. These studies combine multimodal
neuroimaging methods to delineate changes in brain
structure/function associated with risk factors for AD/AAMI
(e.g., Thambisetty
et al., 2010) and employ mass spectrometry-based
proteomic/metabolomic techniques for the identification of
biomarkers related to pathological endophenotypes associated
with neurodegeneration (e.g., Thambisetty et al.,
2010). The research benefits from the unique and rich
longitudinal dataset available in the Baltimore Longitudinal
Study of Aging (BLSA) as well as complementary patient
cohorts such as AddNeuroMed that are available as part of
ongoing international collaborations (e.g., Thambisetty et al.,
2011).
Additional information regarding the NIA/IRP and the
Laboratory of Behavioral Neuroscience (LBN) are available at
the following websites: www.grc.nia.nih.gov/offices.htm
or www.grc.nia.nih.gov/branches/lpc/lbn.htm.
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