This symposium was held in July 2006 at the International Conference on Alzheimer's Disease in Madrid, Spain. The Alzforum editors asked the symposium speakers to consider key advances in Alzheimer disease research from the past decade and to propose agendas for the next 10 years. Our speakers formed teams and prepared short presentations in which they attempted to synthesize major findings in several overlapping subject areas. We are pleased to present videos and select slides of their talks below.

We intended this symposium to serve as a starting point to challenge AD researchers to integrate findings and build inclusive hypotheses that explain more fully the pathogenesis of this complex disease. We welcome your questions, commentaries, and ideas about how to achieve these goals.

Don't miss our series of news reports from this conference.

Presentations

Molecular Pathways Linking Aβ and Tau Pathology
By Frank M. LaFerla

Challenges for the Amyloid Hypothesis?
By Takeshi Iwatsubo and Bart De Strooper

Aging and Alzheimer's Disease
By Bruce Yankner

Chronic Disease Model for AD: Why We Need Antecedent Biomarkers for AD
By David Holtzman

Microglia Aging and Alzheimer's Disease
By Dave Morgan

Genetics of Alzheimer's disease
By Christine Van Broeckhoven

Q & A
Moderated by Dennis Selkoe and Konrad Beyreuther

Comments and Discussion

AD Research Past and Future: View Slides by Takaomi Saido
Slide 1, Slide 2, Slide 3