Here in the tuberomamillary nucleus, part of the posterior hypothalmus, one can see a neuron
loaded with Alz-50 but also when one stains with classical stains. With silver staining you can
see the Alzheimer changes in this part of the nucleus which gives a problem I think to the
evolutionary hypothesis Braak has purposed <>. Compare the
tuberomamillary and the nucleus tuberalis; when we look at the size of the Golgi apparatus in
this area, you see compared to the controls that the size of the Golgi apparatus is much smaller
and so we can give many examples of areas in which the metabolic activity, the synthetic
activity of the neurons, is decreased in Alzheimer's disease.