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|
6548261 |
Alzheimer model for drug screening |
12/30/98 |
4/15/03 |
|
6518235 |
Methods for improving brain function using leptin or analogs thereof |
11/30/98 |
2/11/03 |
|
6514984 |
Treatment for alzheimer's disease |
4/12/00 |
2/4/03 |
|
6514969 |
b-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions |
7/24/01 |
2/4/03 |
|
6511966 |
Mitochondria protecting agents for treating mitochondria associated diseases |
8/20/01 |
1/28/03 |
|
6509381 |
Method of preparing and using compositions extracted from vegetable matter for the treatment of neurological conditions |
5/1/02 |
1/21/03 |
|
6509331 |
Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
6/21/99 |
1/21/03 |
|
6506782 |
Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
2/27/98 |
1/14/03 |
|
6503242 |
Therapeutic method for treatment of Alzheimer's disease |
3/30/00 |
1/7/03 |
|
6495693 |
N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
3/30/99 |
12/17/02 |
|
6492407 |
Pharmaceutical compositions containing triazolones and methods of treating neurodegenerative disease using triazolones |
4/23/01 |
12/10/02 |
|
6486169 |
Botanical drug for treatment and prevention of alzheimer's disease |
2/19/02 |
11/26/02 |
|
6472421 |
Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor |
11/13/98 |
10/29/02 |
|
6471961 |
Interleukin antagonists for the treatment of neurological, retinal and muscular disorders |
5/2/00 |
10/29/02 |
|
6471960 |
Methods for the prevention or treatment of alzheimer's disease |
9/13/00 |
10/29/02 |
|
6469055 |
Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
2/5/01 |
10/22/02 |
|
6469049 |
Method of treating, preventing or inhibiting central nervous system injuries and diseases |
4/20/01 |
10/22/02 |
|
6462171 |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
12/12/96 |
10/8/02 |
|
6451343 |
Composition for treating dementia and Alzheimer's disease |
8/30/00 |
9/17/02 |
|
6451306 |
Methods for therapy of neurodegenerative disease of the brain |
4/15/98 |
9/17/02 |
|
6444662 |
Stable hyperforin salts, method for producing same and their use in the treatment of alzheimer's disease |
8/11/00 |
9/3/02 |
|
6444201 |
Treatment of alzheimer disease by modulation of synapsins |
5/13/96 |
9/3/02 |
|
6436983 |
Treatment for alzheimer's disease |
4/10/00 |
8/20/02 |
|
6436937 |
Use of desoxypeganine in the treatment of Alzheimer's dementia |
8/16/01 |
8/20/00 |
|
6420351 |
Methods for treating neuropsychiatric disorders |
4/13/01 |
7/16/02 |
|
6417229 |
a-sulfonylamino hydroxamic acid inhibitors of matrix metalloproteinases for the treatment of peripheral or central nervous system disorders |
9/27/00 |
7/9/02 |
|
6413940 |
Pharmaceutically active agents that impede the formation of amyloid by impeding the genesis of DMS |
2/3/98 |
7/2/02 |
|
6399628 |
N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds |
3/12/99 |
6/4/02 |
|
6391871 |
Preventing neuronal degeneration in Alzheimer's disease |
9/27/99 |
5/21/02 |
|
6383159 |
Devices and method for removing cerebrospinal fluids from a patient's CSF space |
11/10/98 |
5/7/02 |
|
6369058 |
Brain delivery of folic acid for the prevention of alzheimer's disease and stroke |
1/14/00 |
4/19/02 |
|
6362160 |
Immunophilin-binding agents prevent glutamate neurotoxicity associated with vascular stroke and neurodegenerative diseases |
6/30/93 |
3/26/02 |
|
6358990 |
Method for treating Alzheimer's disease |
4/13/00 |
3/19/02 |
|
6358975 |
Method of using selective parp inhibitors to prevent or treat neurotoxicity |
2/11/00 |
3/19/02 |
|
6353015 |
Method of treating neurodegenerative disorders |
3/23/01 |
3/5/02 |
|
6352715 |
Transdermal rate-controlled delivery of Huperzine A for treatment of
alzheimer's disease |
6/12/00 |
3/5/02 |
|
6346280 |
Composition and methods for inhibiting the formation of brain amyloid
deposits |
11/24/98 |
2/12/02 |
|
6340709 |
Use of matrix metalloproteinase inhibitors for treating neurological
disorders and promoting wound healing |
6/25/98 |
1/22/02 |
|
6333351 |
N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions
comprising same, and methods for inhibiting .beta.-amyloid peptide
release and/or its synthesis by use of such compounds |
5/3/99 |
12/25/01 |
|
6326507 |
Therapeutic compounds and methods of use |
6/17/99 |
12/4/01 |
|
6323218 |
Agents for use in the treatment of Alzheimer's disease |
3/11/98 |
11/27/01 |
|
6323198 |
Preparation and use of a specific GABA-A.alpha.5 receptor ligand
for treatment of alzheimer's disease |
7/20/00 |
11/27/01 |
|
6322824 |
Use of hyperforin and hyperforin-containing extracts in the treatment
of dementia diseases |
8/11/00 |
11/27/01 |
|
6319919 |
Galanthamine derivatives for treatment of alzheimer's disease |
6/7/95 |
11/20/01 |
|
6313152 |
N(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions
comprising same, and methods for inhibiting .beta.-amyloid peptide
release and/or its synthesis by use of such compounds |
9/7/99 |
11/6/01 |
|
6306912 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
6/7/95 |
10/23/01 |
|
6294383 |
Porcine neural cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
9/25/01 |
|
6277828 |
Pharmaceutical formulations of nerve growth factor |
8/20/93 |
8/21/01 |
|
6277372 |
Porcine neural cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
8/21/01 |
|
6274615 |
Method for delaying the onset of alzheimer's disease and for
treatment or delaying the onset of other amyloidosis-related
diseases/disorders |
3/25/99 |
8/14/01 |
|
6274606 |
Methods of treating central nervous system disorders with aryl
substituted olefinic amine compounds |
10/12/98 |
8/14/01 |
|
6269270 |
Apparatus and method for adjunct (add-on) therapy of Dementia
and Alzheimer's disease utilizing an implantable lead and external
stimulator |
10/26/98 |
7/31/01 |
|
6268358 |
Compounds for the treatment of Alzheimer's disease |
6/7/95 |
7/31/01 |
|
6264625 |
Method and apparatus for treating adult-onset dementia of the
Alzheimer's type |
7/25/97 |
7/24/01 |
|
6262302 |
N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical
compositions comprising same, and methods for inhibiting .beta.-amyloid
peptide release and/or its synthesis by use of such compounds |
9/17/99 |
7/17/01 |
|
6252081 |
Process for production of donepezil derivative |
6/27/00 |
6/26/01 |
|
6251928 |
Treatment of alzheimer's disease employing inhibitors of cathepsin
D |
3/16/94 |
6/26/01 |
|
6251903 |
Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
and the use thereof as glycine receptor antagonist |
9/13/00 |
6/26/01 |
|
6251863 |
Method of preventing and treating symptoms of aging and neurodegenerative
dysfunctions with relaxin |
2/18/99 |
6/26/01 |
|
6245911 |
Donepezil polycrystals and process for producing the same |
6/5/00 |
6/12/01 |
|
6245766 |
Method of treating psychiatric conditions |
12/18/98 |
6/12/01 |
|
6245751 |
Methods for the treatment of apolipoprotein E related diseases |
9/10/99 |
6/12/01 |
|
6245736 |
Use of peptidic bradykinin antagonists for the treatment and
prevention of Alzheimer's disease |
10/14/97 |
6/12/01 |
|
6245575 |
Screening of agents for treatment of alzheimer's disease |
7/16/99 |
6/12/01 |
|
6242421 |
Methods for preventing and treating Alzheimer's disease |
6/4/99 |
6/5/01 |
|
6239111 |
In vivo method of improving survival rate of brain neurons |
1/26/98 |
5/29/01 |
|
6235769 |
Methods of preventing and treating neurological disorders with
compounds that modulate the function of the C-RET receptor protein
tyrosine kinase |
7/2/98 |
5/22/01 |
|
6228878 |
Methods for treating or preventing alzheimer's disease using
substituted 2-aryl-3-morpholinopropanones |
8/10/99 |
5/8/01 |
|
6228875 |
Methods for treating neuropsychiatric disorders |
4/14/99 |
5/8/01 |
|
6218405 |
Heteroarylsulfonamide derivatives and pharmaceutical compositions
containing them |
6/16/99 |
4/17/01 |
|
6218404 |
Subtype-selective NMDA receptor ligands and the use thereof |
9/16/98 |
4/17/01 |
|
6218383 |
Pharmaceutical compositions for the prevention and treatment
of central nervous system disorders |
8/7/98 |
4/17/01 |
|
6214334 |
Compositions and methods for producing and using homogenous neuronal
cell transplants to treat neurodegenerative disorders and brain
and spinal cord injuries |
5/3/99 |
4/10/01 |
|
6211245 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
11/4/98 |
4/3/01 |
|
6211235 |
Compounds for inhibiting .beta.-amyloid peptide release and/or
its synthesis |
9/30/98 |
4/3/01 |
|
6207803 |
Human requiem |
1/19/99 |
3/27/01 |
|
6207710 |
Compounds for inhibiting .beta.-amyloid peptide release and/or
its synthesis |
9/30/98 |
3/27/01 |
|
6204281 |
Method of treatment and pharmaceutical composition |
7/8/99 |
3/20/01 |
|
6204053 |
Porcine cortical cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
3/20/01 |
|
6200990 |
Neuroprotective agents having antioxidant and NMDA antagonist
activity |
12/14/99 |
3/13/01 |
|
6194581 |
Substituted pyridines useful as modulators of acetylcholine receptors |
12/22/98 |
2/27/01 |
|
6194404 |
Process for the isolation of galanthamine |
8/7/98 |
2/27/01 |
|
6194403 |
Tacrine derivatives for treating Alzheimer's disease |
9/9/99 |
2/27/01 |
|
6191166 |
Methods and compounds for inhibiting .beta.-amyloid peptide release
and/or its synthesis |
11/21/97 |
2/20/01 |
|
6191154 |
Compositions and methods for the treatment of Alzheimer's disease,
central nervous system injury, and inflammatory diseases |
11/27/98 |
2/20/01 |
|
6187785 |
Agent for treating neurodegenerative disorders |
3/25/99 |
2/13/01 |
|
6187756 |
Composition and methods for treatment of neurological disorders
and neurodegenerative diseases |
1/28/00 |
2/13/01 |
|
6184248 |
Compositions and methods for treatment of neurological disorders
and neurodegenerative diseases |
11/8/99 |
2/6/01 |
|
6184236 |
Method of treating a neurodegenerative disease by administering
an aryl-cyclohexylamine derivative |
8/9/99 |
2/6/01 |
|
6180603 |
Method for administering neurologic agents to the brain |
1/8/97 |
1/30/01 |
|
6177472 |
Regulation of alzheimer's disease proteins and uses thereof |
10/27/98 |
1/23/01 |
|
6177077 |
TNT inhibitors for the treatment of neurological disorders |
12/31/99 |
1/23/01 |
|
6172055 |
Apoptosis inhibitors for treating neurodegenerative diseases |
8/14/98 |
1/9/01 |
|
6172043 |
Treatments for neurotoxicity in Alzheimer's disease caused by
.beta. amyloid peptides |
1/9/98 |
1/9/01 |
|
6172041 |
Use of conantokins |
2/10/99 |
1/9/01 |
|
6169115 |
Use of aminoguanidine analogs for the treatment of diseases of
the nervous system |
5/21/99 |
1/2/01 |
|
6166209 |
Piperidine derivatives |
11/20/98 |
12/26/00 |
|
6161044 |
Method and apparatus for treating chronic pain syndromes, tremor,
dementia and related disorders and for inducing electroanesthesia
using high frequency, high intensity transcutaneous electrical
nerve stimulation |
11/23/98 |
12/12/00 |
|
6153652 |
N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical
compositions comprising same, and methods for inhibiting .beta.-amyloid
peptide release and/or its synthesis by use of such compounds |
11/21/97 |
11/28/00 |
|
6150354 |
Compounds for the treatment of Alzheimer's disease |
10/19/93 |
11/21/00 |
|
6140369 |
Benzamides for neurodegenerative disorder treatment |
9/7/99 |
10/31/00 |
|
6136832 |
5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones and methods of
use therefor |
5/19/99 |
10/24/00 |
|
6136548 |
Methods for identifying useful T-PA mutant derivatives for treatment
of vascular hemorrhaging |
9/2/99 |
10/24/00 |
|
6133299 |
Methods for treating neurodegenerative diseases and disorders
using N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas and other
anticonvulsant compounds |
2/25/93 |
10/17/00 |
|
6133259 |
Alkyl, alkenyl and alkynyl chrysamine G derivatives for inhibition
of cell degeneration and toxicity associated with amyloid deposition |
11/9/98 |
10/17/00 |
|
6127370 |
Method for treating alzheimer's disease |
11/8/99 |
10/3/00 |
|
6124456 |
Pyrazolopyridine compound and pharmaceutical use thereof |
1/19/99 |
9/26/00 |
|
6117912 |
Sublingual and buccal administration
of selegiline for treating certain selegiline-responsive diseases
and conditions |
4/28/98 |
9/12/00 |
|
6114365 |
Arylmethyl-carbonylamino-thiazole
derivatives, process for their preparation, and their use as
antitumor agents |
8/12/99 |
9/5/00 |
|
6114334 |
Piperazine derivatives as therapeutic
agents |
12/17/97 |
9/5/00 |
|
6107310 |
Heteroarylcarboxamide derivatives
for treating CNS disorders |
6/16/98 |
8/22/00 |
|
6103754 |
Agent for potentiating nerve growth
factor activity containing 1,2-ethanediol derivative or salt
thereof |
3/9/98 |
8/15/00 |
|
6100269 |
Pharmaceutical compositions for
prevention and treatment of central nervous system disorders |
5/6/99 |
8/8/00 |
|
6087372 |
Method of enhancing cognition with 2-(4-methoxyphenyl)-pyrazolo[4,3-c]quinolin-3-one |
5/25/99 |
7/11/00 |
|
6077852 |
Treatment of central nervous system disorders with selective
estrogen receptor modulators |
4/9/98 |
6/20/00 |
|
6071970 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
6/7/95 |
6/6/00 |
|
6071694 |
Screening method for therapeutic agents against Alzheimer's disease |
6/5/95 |
6/6/00 |
|
6060516 |
N.sup.1 -propargylhydrazines, N.sup.2 -propargylhydrazines and
their analogs for the treatment of depression, anxiety and neurodegeneration |
2/17/98 |
5/9/00 |
|
6060048 |
Method for transplanting cells into the brain and therapeutic
uses therefor |
6/2/95 |
5/9/00 |
|
6056725 |
Therapeutic method for treatment of alzheimer's disease |
8/3/98 |
5/2/00 |
|
6051684 |
Methods of treating neurodegenerative disorders using protease
inhibitors |
5/17/95 |
4/18/00 |
|
6051610 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
2/18/99 |
4/18/00 |
|
6043224 |
Compositions and methods for treatment of neurological disorders
and neurodegenerative diseases |
9/5/97 |
3/28/00 |
|
6037327 |
Specific saccharide compositions and methods for treating Alzheimer's
disease and other amyloidoses |
8/28/98 |
3/14/00 |
|
6034119 |
Agent for potentiating nerve growth factor activity containing
1,2-ethanediol derivative or salt thereof |
2/18/99 |
3/7/00 |
|
6034080 |
Use of Maillard reaction inhibitors for the treatment of amyloidosis-based
disease |
12/4/98 |
3/7/00 |
|
6030984 |
Pyridone compounds useful in treating Alzheimer's disease |
9/28/98 |
2/29/00 |
|
6025395 |
Method of preventing or delaying the onset and progression of
Alzheimer's disease and related disorders |
4/14/97 |
2/15/00 |
|
6022859 |
Inhibitors of .beta.-amyloid toxicity |
11/14/97 |
2/8/00 |
|
6017965 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
12/11/96 |
1/25/00 |
|
6017913 |
Naphthylazo inhibition of amyloidosis |
5/3/99 |
1/25/00 |
|
5990132 |
Polycyclic systems, and derivatives thereof, as neurotransmitter
release enhancers useful in the treatment of cognitive disorders |
6/17/96 |
11/23/99 |
|
5985936 |
Method of preventing and delaying onset of Alzheimer's disease
and composition therefore |
12/18/97 |
11/16/99 |
|
5985930 |
Treatment of neurodegenerative conditions with nimesulide |
4/1/97 |
11/16/99 |
|
5985581 |
Use of presenilin-1 for diagnosis of alzheimers disease |
7/17/97 |
11/16/99 |
|
5981508 |
Facilitation of repair of neural injury with CM101/GBS toxin |
1/29/97 |
11/9/99 |
|
5980933 |
Transdermal formulation of xanomeline |
9/29/97 |
11/9/99 |
|
5980480 |
Method and apparatus for treating adult-onset dementia of the
alzheimer's type |
7/11/96 |
11/9/99 |
|
5977181 |
Therapeutic uses for nitric oxide inhibitors |
11/13/97 |
11/2/99 |
|
5972956 |
Inhibition of amyloidosis by 9-acridinones |
4/29/98 |
10/26/99 |
|
5958964 |
Use of melatonin to prevent cytotoxic effects of amyloid beta
protein |
2/18/97 |
9/28/99 |
|
5958919 |
Treatment of presymptomatic alzheimer's disease to prevent neuronal
degeneration |
9/20/96 |
9/28/99 |
|
5952349 |
Muscarinic antagonists for treating memory loss |
7/8/97 |
9/14/99 |
|
5948800 |
Preventive or therapeutic drug for Alzheimer's disease |
8/4/97 |
9/7/99 |
|
5948763 |
Peptides and pharmaceutical compositions thereof for treatment
of disorders or diseases associated with abnormal protein folding
into amyloid or amyloid-like deposits |
4/10/96 |
9/7/99 |
|
5928882 |
Treatment and prevention of neurodegenerative diseases using
modulators of Fe65 |
10/24/97 |
7/27/99 |
|
5900409 |
Cerebration improver |
11/2/95 |
5/4/99 |
|
5891887 |
Uses of [R-(Z)]-.alpha.-(methoxyimino)-.alpha.-(1-azabicyclo
[2.2.2.] oct-3-yl) |
4/25/97 |
4/6/99 |
|
5891923 |
R-enantiomer of N-propargyl-1-aminoindan for the treatment of
dementia |
6/6/95 |
4/6/99 |
|
5886023 |
Agent for improving dementia |
5/22/95 |
3/23/99 |
|
5880116 |
Use of celastrol to treat alzheimer's disease |
12/13/96 |
3/09/99 |
|
5880256 |
Factor VIIa inhibitors from Kunitz domain proteins |
3/03/95 |
3/09/99 |
|
5877173 |
Preventing neuronal degeneration in Alzheimer's disease |
8/28/96 |
3/2/99 |
|
5876948 |
Screening methods to identify neurotoxin inhibitors |
7/29/91 |
3/2/99 |
|
5874424 |
Inhibitors of interleukin-1.beta. converting enzyme |
2/8/96 |
2/23/99 |
|
5874421 |
Manganese complexes of nitrogen-containing macrocyclic ligands
effective as catalysts for dismutating superoxide |
6/6/95 |
2/23/99 |
|
5874277 |
Proteins, their production and use |
4/4/97 |
2/23/99 |
|
5872101 |
Methods of treating neurodegenerative disorders using protease
inhibitors |
5/18/95 |
2/16/99 |
|
5869500 |
Pyridone compounds useful in treating Alzheimer's disease |
11/24/97 |
2/9/99 |
|
5864018 |
Antibodies to advanced glycosylation end-product receptor polypeptides
and uses therefor |
4/16/96 |
1/26/99 |
|
5863893 |
Factor VIIa inhibitors from kunitz domain proteins |
3/3/95 |
1/26/99 |
|
5863902 |
Methods of treating neurodegenerative disorders using protease
inhibitors |
5/18/95 |
1/26/99 |
|
5856169 |
Isoforms of human interleukin-1.beta. converting enzyme and methods
of using the same |
2/21/95 |
1/5/99 |
|
5854215 |
Modulators of .beta.-amyloid peptide aggregation |
6/07/95 |
12/29/98 |
|
5854204 |
A.beta. peptides that modulate beta.-amyloid aggregation |
5/14/95 |
12/29/98 |
|
5851996 |
Materials and methods for treatment of plaquing diseases |
2/13/98 |
12/22/98 |
|
5849782 |
Methods of inhibiting neurodegenerative diseases |
7/12/96 |
12/15/98 |
|
5847135 |
Inhibitors of interleukin-1.beta. converting enzyme |
5/25/95 |
12/8/98 |
|
5847074 |
Phospholipase C-inhibiting peptides |
5/5/95 |
12/8/98 |
|
5843904 |
Inhibitors of interleukin-1.beta.converting enzyme |
12/20/95 |
12/1/98 |
|
5843695 |
Method for decomposing amyloid protein precursor and amyloid
.beta.-protein |
4/30/96 |
12/1/98 |
|
5840746 |
Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative
diseases |
9/5/97 |
11/24/98 |
|
5837853 |
Preventive or therapeutic agents for alzheimers disease a screening
method of alzheimers disease and tau-protein kinase I originated
from human being |
2/20/96 |
11/17/98 |
|
5837707 |
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
|
6/6/95 |
11/17/98 |
|
5834244 |
Factor VIIa inhibitors from Kunitz domain proteins |
3/3/95 |
11/10/98 |
|
5833988 |
Transferrin receptor specific antibody- neuropharmaceutical or
diagnostic agent conjugates |
4/18/96 |
11/10/98 |
|
5830910 |
Cytochalasins useful in providing protection against nerve cell
injury associated with neurodegenerative disorders |
10/23/95 |
11/3/98 |
|
5830896 |
Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
6/7/95 |
11/3/98 |
|
5824692 |
Pharmaceutical compositions for prevention and treatment of central
nervous system disorders |
1/6/95 |
10/20/98 |
|
5817656 |
Mental Disorders (2-Methyl-4-(4-methyl-1- piperazinyl)-10H-thieno-[2,3-b][1,5]benzodiazepine |
11/13/96 |
10/6/98 |
|
5817655 |
Methods of treatment using a thieno- benzodiazepine |
11/13/96 |
10/6/98 |
|
5817626 |
Modulators of beta-amyloid peptide aggregation |
3/14/95 |
10/6/98 |
|
5804560 |
Peptide and peptide analog protease inhibitors |
1/6/95 |
9/8/98 |
|
5807871 |
Piperidine derivatives having anxiolytic effect |
6/7/95 |
9/15/98 |
|
5807887 |
Agent for potentiating nerve growth factor activity containing
1,2-ethanediol derivative or salt thereof |
4/23/97 |
9/15/98 |
|
5804560 |
Peptide and petide analogs of protease inhibitors |
1/6/95 |
9/8/98 |
|
5801184 |
Carbon monoxide dependent guanylyl cyclase modifiers and methods
of use |
6/8/95 |
9/1/98 |
|
5798102 |
Treatment of cardiomyopathy |
3/4/97 |
8/25/98 |
|
5795954 |
Factor VIIa inhibitors from Kunitz domain proteins |
3/4/94 |
8/18/98 |
|
5786328 |
Use of kunitz type plasma kallikrein inhibitors |
6/5/95 |
7/28/98 |
|
5786187 |
Method for reducing neuronal degeneration associated with seizure |
9/21/95 |
7/28/98 |
|
5780587 |
Compounds and methods for inhibiting .beta.-protein filament
formation and neurotoxicity |
4/6/95 |
7/14/98 |
|
5780265 |
Kunitz type plasma kallikrein inhibitors |
6/5/95 |
7/14/98 |
|
5778893 |
Method of diagnosing and monitoring a treatment for Alzheimer's
disease |
5/19/95 |
7/14/98 |
|
5776946 |
Peripheral benzodiazepine receptor ligands as antiinflammatory
agents |
8/28/95 |
7/7/98 |
|
5773466 |
Pharmaceutical product comprising sympathomimetic drug havingtherapeutic
properties on the human sensibility and autocinesis in general |
11/1/96 |
6/30/98 |
|
5762953 |
Transdermal propentofylline compositions for the treatment of
Alzheimers disease |
8/22/96 |
6/9/98 |
|
5756482 |
Method of attenuation of nervous system damage |
6/16/96 |
5/26/98 |
|
5756084 |
Human stromal derived factor 1.alpha. and 1.beta. |
7/1/96 |
5/26/98 |
|
5753624 |
Materials and methods for treatment of plaquing disease |
8/8/96 |
5/19/98 |
|
5750542 |
Benzisoxazole and benzisothizole derivatives as cholinesterase
inhibitors |
9/28/93 |
5/12/98 |
|
5744476 |
Dopamine D.sub.1 agonists for the treatment of dementia |
6/27/94 |
4/28/98 |
|
5736546 |
1,4-(diphenlyalkyl) piperazine derivatives |
3/25/96 |
4/7/98 |
|
5733926 |
Isoflavonoids for treatment and prevention of alzheimer dementia
and reduced cognitive functions |
12/13/96 |
3/31/98 |
|
5723496 |
Method for prevention and treatment of harmful effects of intracellular
acidosis |
3/15/95 |
3/3/98 |
|
5716929 |
Inhibitors of interleukin-1.beta. converting enzyme |
6/5/95 |
2/10/98 |
|
5714471 |
Peptide and peptide analog protease inhibitors |
5/17/95 |
2/3/98 |
|
5708007 |
2-(piperidin-4-yl, pyridin-4-yl and tetrahydropyridin- 4-yl)
benzofuran-7-ol and carbamate derivatives for treating memory
dysfunction |
8/27/96 |
1/13/98 |
|
5693668 |
Acetylcholinesterase inhibitors |
1/31/95 |
12/2/97 |
|
5693614 |
Drug for the treatment of senile dementia of the ischemic and
hypoglycemic types |
6/14/94 |
12/2/97 |
|
5691368 |
Substituted oxazolidine calpain and/or cathepsin B inhibitors |
12/11/95 |
11/25/97 |
|
5691201 |
Use of sabeluzole in chronic neurodegenerative diseases |
10/11/95 |
11/25/97 |
|
5684012 |
Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
6/7/95 |
11/4/97 |
|
5683422 |
Method and apparatus for treating neurodegenerative disorders
by electrical brain stimulation |
4/25/96 |
11/4/97 |
|
5665725 |
Piperidine derivatives having anxiolytic effect |
12/13/93 |
9/9/97 |
|
5665706 |
Nerve growth induction, stimulation and maintenance and enzyme
potentiation |
10/12/95 |
9/9/97 |
|
5658924 |
1,8-naphthyridin-2-one derivative and use thereof |
6/1/95 |
8/19/97 |
|
5658921 |
Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
12/12/94 |
8/19/97 |
|
5656627 |
Inhibitors of interleukin-1.beta. converting enzyme |
3/17/95 |
8/12/97 |
|
5650148 |
Method of grafting genetically modified cells to treat defects,
disease or damage of the central nervous system |
3/10/94 |
7/22/97 |
|
5643960 |
Method of delaying onset of alzheimer's disease symptoms |
4/15/94 |
7/1/97 |
|
5629165 |
Neural calcium-activated neutral proteinase inhibitors |
2/25/94 |
5/13/97 |
|
5605897 |
2-methyl-thieno-benzodiazepine |
2/13/95 |
2/25/97 |
|
5594000 |
Spirofurane derivatives |
6/6/95 |
1/14/97 |
|
5583140 |
Pharmaceutical compositions for the treatment of central nervous
system disorders |
5/17/95 |
12/10/96 |
|
5580898 |
Method of stabilizing microtubules |
5/24/94 |
12/3/96 |
|
5576353 |
Method of treating memory disorders using R-enantiomers of N-propargyl-aminoindan
compounds |
6/2/95 |
11/19/96 |
|
5567724 |
Alkaline and acid phosphatase inhibitors in treatment of neurological
disorders |
6/1/94 |
10/22/96 |
|
5547965 |
Use of substituted amines for the treatment of brain function
disorders |
4/19/95 |
8/20/96 |
|
5538983 |
Method of treating amyloidosis by modulation of calcium |
4/29/94 |
7/23/96 |
|
5538968 |
Geneserine derivatives processes as cholinesterase inhibitors |
3/3/94 |
7/23/96 |
|
5535760 |
Method for detecting and treating Alzheimer's disease |
3/24/95 |
7/16/96 |
|
5532219 |
Dapsone and promin for the treatment of dementia |
4/5/93 |
7/2/96 |
|
5523295 |
Method for treating and preventing alzheimer's disease |
7/6/94 |
6/4/96 |
|
5516772 |
K-252 derivatives which enhance neurotrophin-induced activity
|
9/16/94 |
5/14/96 |
|
5506097 |
Method for inhibiting .beta.-protein enzymatic activity |
1/10/94 |
4/9/96 |
|
5492913 |
N-benzylpiperazine compounds |
3/23/94 |
2/20/96 |
|
5486541 |
Monofluorinated derivatives of N-propargyl-1- aminoindan and
their use as inhibitors of monoamine oxidase |
9/22/94 |
1/23/96 |
|
5482938 |
Azabicyclo and azacyclo oxime and amine cholinergic agents and
methods of treatment |
2/1/94 |
1/9/96 |
|
5480645 |
Hydroxyamines N-acyl derivatives having scavenger activity and
useful in acute and chronic pathologies associated with peroxidation
and inflammation phenomena |
12/29/93 |
1/2/96 |
|
5478857 |
Use of PLA2 inhibitors as treatment for alzheimer's disease |
12/23/93 |
12/26/95 |
|
5470951 |
Peptides for antagonizing the effects of amyloid .beta.protein |
9/29/93 |
11/28/95 |
|
5468726 |
Treatment of neuropsychiatric disorders |
2/23/90 |
11/21/95 |
|
5457133 |
R-enantiomers of N-propargyl-aminoindan compounds, their preparation
and pharmaceutical compositions containing them |
2/17/94 |
10/10/95 |
|
5453428 |
Method and composition for the treatment of apathy-amotivation
syndrome |
9/7/93 |
9/26/95 |
|
5447939 |
Carbon monoxide dependent guanylyl cyclase modifiers and methods
of use |
7/25/94 |
9/5/95 |
|
5428043 |
Tricyclic-cyclic amines as novel cholinesterase inhibitors |
10/29/92 |
6/27/95 |
|
5399565 |
Pyrazolidinone CCK and gastrin antagonists and pharmaceutical
formulations thereof |
11/12/93 |
3/21/95 |
|
5385915 |
Treatment of amyloidosis associated with Alzheimer disease using
modulators of protein phosphorylation |
6/7/93 |
1/31/95 |
|
5380878 |
Benzo[b]thiophen-5-yl derivative and process for producing the
same |
3/29/94 |
1/10/95 |
|
5306718 |
Oxime and amine substituted azabicyclo and azocyclo muscarinic
agonists and methods of treatment |
10/16/91 |
4/26/94 |
|
5290793 |
Dihydrocaffeic acid derivatives and pharmaceutical preparation
containing same |
10/29/92 |
3/1/94 |
|
5276059 |
Inhibition of diseases associated with amyloid formation |
7/10/92 |
1/4/94 |
|
5254552 |
Aryl-and heteroaryl piperazinyl carboxamides having central nervous
system activity |
3/16/92 |
10/19/93 |
|
5247091 |
Preparation of enamines in aqueous media |
7/30/92 |
9/21/93 |
|
5244897 |
Glycyl-p-amino-pyridine for the treatment of senile dementia
states |
6/2/92 |
9/14/93 |
|
5242932 |
Treatment of amyloidosis associated with Alzheimer disease |
12/17/91 |
9/7/93 |
|
5232923 |
Catechol derivatives and pharmaceuticalpreparations containing
same |
4/22/91 |
8/3/93 |
|
5214034 |
Catechol derivatives, and preventive and remedial preparations
for regressive disorders in the central nervous system containing
the same |
12/3/91 |
5/25/93 |
|
5192753 |
Anti-rheumatoid arthritic drugs in the treatment of dementia |
4/23/91 |
3/9/93 |
|
5137878 |
Composition and method for treatment of senile dementia |
9/13/91 |
8/11/92 |
|
5137873 |
Substance P and tachykinin agonists for treatment of Alzheimer's
disease |
8/11/92 |
7/27/90 |
|
5106849 |
Use of aryl- and heteroaryl piperazinylcarboxamides in the treatment
of various CNS disorders |
4/22/91 |
4/21/92 |
|
5102906 |
Catechol derivatives, and preventive and remedial preparations
for regressive disorders in the central nervous system containing
the same |
10/31/90 |
4/7/92 |
|
5100901 |
Cyclic amine compounds and pharmaceutical use |
10/18/89 |
3/31/92 |
|
5091432 |
9-substituted hypoxanthine bi-functional compounds and their
neuroimmunological methods of use |
3/28/90 |
2/25/92 |
|
5059595 |
Pharmaceutical compositions containing 5-methyltetrahydrofolic
acid, 5-formyltetrahydrofolic acid and their pharmaceutically
acceptable salts in controlled-release form active in the therapy
of organic mental disturbances |
3/20/90 |
10/22/91 |
|
5051410 |
Method and composition for enhancing the release of neurotransmitters |
9/1/88 |
9/24/91 |
|
5047405 |
Antiamnesic use of pteridine derivatives |
2/27/90 |
9/10/91 |
|
5026733 |
Brain function-improving medicine |
11/17/89 |
6/25/91 |
|
5025033 |
Alkylene diamines |
1/25/89 |
6/18/91 |
|
5019574 |
3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetra hydroquinoline
compounds useful for improving psychoneural function |
9/28/89 |
5/28/91 |
|
4985458 |
Catechol diacetate derivatives for inducing the production of
nerve growth factor to treat degenerative diseases in the central
nervous system |
2/20/90 |
1/15/91 |
|
4966893 |
Method for treatment of senile dementia |
1/13/89 |
10/30/90 |
|
4945092 |
Substituted 1-(oxopyrrolidinylalkanoyl)- piperazines useful as
nootropics |
6/19/89 |
7/31/90 |
|
4939124 |
Treatment and diagnosis of dementia |
1/26/88 |
7/3/90 |
|
4923696 |
Method to prepare a neurotrophic composition |
4/22/88 |
5/8/90 |
|
4906626 |
Method of use for treatment or prevention of cognitive disorders |
1/13/89 |
3/6/90 |
|
4895841 |
Cyclic amine compounds with activity against acetylcholinesterase |
6/20/88 |
1/23/90 |
|
4894393 |
Dithiocarbamate-choline adduts and use thereof in treatment of
brain diseases |
9/16/88 |
1/16/90 |
|
4863930 |
Use of substituted 5H-pyrido- and 5H-thiazolo(2',1':2,3) imidazo
(4,5-b)indoles as cholinomimetic agents |
12/19/86 |
9/5/89 |
|
4837240 |
Aminoalkyl secocanthine derivatives and their use |
1/30/87 |
6/6/89 |
|
4814339 |
Treatment for Alzheimer's disease |
2/11/86 |
3/21/89 |
|
4804665 |
Azaspiro compounds and their use |
12/24/87 |
2/14/89 |
|
4784999 |
Novel treatment |
9/11/87 |
11/15/88 |
|
4782077 |
Taliscanin and other aristolactams for treating neurological
disorders, Parkinson's disease, Alzheimer disease and impotence |
8/20/87 |
11/1/88 |
|
4752610 |
N-(pyrrol-1-yl)pyridinamines having memory enhancing properties |
12/4/85 |
6/21/88 |
|
4690949 |
Therapeutic drug for dementia |
4/29/86 |
9/1/87 |
|
4684482 |
Orally effective ion chelators |
1/26/84 |
8/4/87 |
|
4481206 |
Spiro succinimide derivative in the treatment of dementia of
the Alzheimer type |
6/20/83 |
11/6/84 |
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