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|
6548261 |
Alzheimer model for drug screening |
12/30/98 |
4/15/03 |
|
6518235 |
Methods for improving brain function using leptin or analogs thereof |
11/30/98 |
2/11/03 |
|
6514984 |
Treatment for alzheimer's disease |
4/12/00 |
2/4/03 |
|
6514969 |
b-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions |
7/24/01 |
2/4/03 |
|
6511966 |
Mitochondria protecting agents for treating mitochondria associated diseases |
8/20/01 |
1/28/03 |
|
6509381 |
Method of preparing and using compositions extracted from vegetable matter for the treatment of neurological conditions |
5/1/02 |
1/21/03 |
|
6509331 |
Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
6/21/99 |
1/21/03 |
|
6506782 |
Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
2/27/98 |
1/14/03 |
|
6503242 |
Therapeutic method for treatment of Alzheimer's disease |
3/30/00 |
1/7/03 |
|
6495693 |
N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting b-amyloid peptide release and/or its synthesis by use of such compounds |
3/30/99 |
12/17/02 |
|
6492407 |
Pharmaceutical compositions containing triazolones and methods of treating neurodegenerative disease using triazolones |
4/23/01 |
12/10/02 |
|
6486169 |
Botanical drug for treatment and prevention of alzheimer's disease |
2/19/02 |
11/26/02 |
|
6472421 |
Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor |
11/13/98 |
10/29/02 |
|
6471961 |
Interleukin antagonists for the treatment of neurological, retinal and muscular disorders |
5/2/00 |
10/29/02 |
|
6471960 |
Methods for the prevention or treatment of alzheimer's disease |
9/13/00 |
10/29/02 |
|
6469055 |
Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
2/5/01 |
10/22/02 |
|
6469049 |
Method of treating, preventing or inhibiting central nervous system injuries and diseases |
4/20/01 |
10/22/02 |
|
6462171 |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
12/12/96 |
10/8/02 |
|
6451343 |
Composition for treating dementia and Alzheimer's disease |
8/30/00 |
9/17/02 |
|
6451306 |
Methods for therapy of neurodegenerative disease of the brain |
4/15/98 |
9/17/02 |
|
6444662 |
Stable hyperforin salts, method for producing same and their use in the treatment of alzheimer's disease |
8/11/00 |
9/3/02 |
|
6444201 |
Treatment of alzheimer disease by modulation of synapsins |
5/13/96 |
9/3/02 |
|
6436983 |
Treatment for alzheimer's disease |
4/10/00 |
8/20/02 |
|
6436937 |
Use of desoxypeganine in the treatment of Alzheimer's dementia |
8/16/01 |
8/20/00 |
|
6420351 |
Methods for treating neuropsychiatric disorders |
4/13/01 |
7/16/02 |
|
6417229 |
a-sulfonylamino hydroxamic acid inhibitors of matrix metalloproteinases for the treatment of peripheral or central nervous system disorders |
9/27/00 |
7/9/02 |
|
6413940 |
Pharmaceutically active agents that impede the formation of amyloid by impeding the genesis of DMS |
2/3/98 |
7/2/02 |
|
6399628 |
N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds |
3/12/99 |
6/4/02 |
|
6391871 |
Preventing neuronal degeneration in Alzheimer's disease |
9/27/99 |
5/21/02 |
|
6383159 |
Devices and method for removing cerebrospinal fluids from a patient's CSF space |
11/10/98 |
5/7/02 |
|
6369058 |
Brain delivery of folic acid for the prevention of alzheimer's disease and stroke |
1/14/00 |
4/19/02 |
|
6362160 |
Immunophilin-binding agents prevent glutamate neurotoxicity associated with vascular stroke and neurodegenerative diseases |
6/30/93 |
3/26/02 |
|
6358990 |
Method for treating Alzheimer's disease |
4/13/00 |
3/19/02 |
|
6358975 |
Method of using selective parp inhibitors to prevent or treat neurotoxicity |
2/11/00 |
3/19/02 |
|
6353015 |
Method of treating neurodegenerative disorders |
3/23/01 |
3/5/02 |
|
6352715 |
Transdermal rate-controlled delivery of Huperzine A for treatment of
alzheimer's disease |
6/12/00 |
3/5/02 |
|
6346280 |
Composition and methods for inhibiting the formation of brain amyloid
deposits |
11/24/98 |
2/12/02 |
|
6340709 |
Use of matrix metalloproteinase inhibitors for treating neurological
disorders and promoting wound healing |
6/25/98 |
1/22/02 |
|
6333351 |
N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions
comprising same, and methods for inhibiting .beta.-amyloid peptide
release and/or its synthesis by use of such compounds |
5/3/99 |
12/25/01 |
|
6326507 |
Therapeutic compounds and methods of use |
6/17/99 |
12/4/01 |
|
6323218 |
Agents for use in the treatment of Alzheimer's disease |
3/11/98 |
11/27/01 |
|
6323198 |
Preparation and use of a specific GABA-A.alpha.5 receptor ligand
for treatment of alzheimer's disease |
7/20/00 |
11/27/01 |
|
6322824 |
Use of hyperforin and hyperforin-containing extracts in the treatment
of dementia diseases |
8/11/00 |
11/27/01 |
|
6319919 |
Galanthamine derivatives for treatment of alzheimer's disease |
6/7/95 |
11/20/01 |
|
6313152 |
N(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions
comprising same, and methods for inhibiting .beta.-amyloid peptide
release and/or its synthesis by use of such compounds |
9/7/99 |
11/6/01 |
|
6306912 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
6/7/95 |
10/23/01 |
|
6294383 |
Porcine neural cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
9/25/01 |
|
6277828 |
Pharmaceutical formulations of nerve growth factor |
8/20/93 |
8/21/01 |
|
6277372 |
Porcine neural cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
8/21/01 |
|
6274615 |
Method for delaying the onset of alzheimer's disease and for
treatment or delaying the onset of other amyloidosis-related
diseases/disorders |
3/25/99 |
8/14/01 |
|
6274606 |
Methods of treating central nervous system disorders with aryl
substituted olefinic amine compounds |
10/12/98 |
8/14/01 |
|
6269270 |
Apparatus and method for adjunct (add-on) therapy of Dementia
and Alzheimer's disease utilizing an implantable lead and external
stimulator |
10/26/98 |
7/31/01 |
|
6268358 |
Compounds for the treatment of Alzheimer's disease |
6/7/95 |
7/31/01 |
|
6264625 |
Method and apparatus for treating adult-onset dementia of the
Alzheimer's type |
7/25/97 |
7/24/01 |
|
6262302 |
N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical
compositions comprising same, and methods for inhibiting .beta.-amyloid
peptide release and/or its synthesis by use of such compounds |
9/17/99 |
7/17/01 |
|
6252081 |
Process for production of donepezil derivative |
6/27/00 |
6/26/01 |
|
6251928 |
Treatment of alzheimer's disease employing inhibitors of cathepsin
D |
3/16/94 |
6/26/01 |
|
6251903 |
Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
and the use thereof as glycine receptor antagonist |
9/13/00 |
6/26/01 |
|
6251863 |
Method of preventing and treating symptoms of aging and neurodegenerative
dysfunctions with relaxin |
2/18/99 |
6/26/01 |
|
6245911 |
Donepezil polycrystals and process for producing the same |
6/5/00 |
6/12/01 |
|
6245766 |
Method of treating psychiatric conditions |
12/18/98 |
6/12/01 |
|
6245751 |
Methods for the treatment of apolipoprotein E related diseases |
9/10/99 |
6/12/01 |
|
6245736 |
Use of peptidic bradykinin antagonists for the treatment and
prevention of Alzheimer's disease |
10/14/97 |
6/12/01 |
|
6245575 |
Screening of agents for treatment of alzheimer's disease |
7/16/99 |
6/12/01 |
|
6242421 |
Methods for preventing and treating Alzheimer's disease |
6/4/99 |
6/5/01 |
|
6239111 |
In vivo method of improving survival rate of brain neurons |
1/26/98 |
5/29/01 |
|
6235769 |
Methods of preventing and treating neurological disorders with
compounds that modulate the function of the C-RET receptor protein
tyrosine kinase |
7/2/98 |
5/22/01 |
|
6228878 |
Methods for treating or preventing alzheimer's disease using
substituted 2-aryl-3-morpholinopropanones |
8/10/99 |
5/8/01 |
|
6228875 |
Methods for treating neuropsychiatric disorders |
4/14/99 |
5/8/01 |
|
6218405 |
Heteroarylsulfonamide derivatives and pharmaceutical compositions
containing them |
6/16/99 |
4/17/01 |
|
6218404 |
Subtype-selective NMDA receptor ligands and the use thereof |
9/16/98 |
4/17/01 |
|
6218383 |
Pharmaceutical compositions for the prevention and treatment
of central nervous system disorders |
8/7/98 |
4/17/01 |
|
6214334 |
Compositions and methods for producing and using homogenous neuronal
cell transplants to treat neurodegenerative disorders and brain
and spinal cord injuries |
5/3/99 |
4/10/01 |
|
6211245 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
11/4/98 |
4/3/01 |
|
6211235 |
Compounds for inhibiting .beta.-amyloid peptide release and/or
its synthesis |
9/30/98 |
4/3/01 |
|
6207803 |
Human requiem |
1/19/99 |
3/27/01 |
|
6207710 |
Compounds for inhibiting .beta.-amyloid peptide release and/or
its synthesis |
9/30/98 |
3/27/01 |
|
6204281 |
Method of treatment and pharmaceutical composition |
7/8/99 |
3/20/01 |
|
6204053 |
Porcine cortical cells and their use in treatment of neurological
deficits due to neurodegenerative diseases |
4/19/95 |
3/20/01 |
|
6200990 |
Neuroprotective agents having antioxidant and NMDA antagonist
activity |
12/14/99 |
3/13/01 |
|
6194581 |
Substituted pyridines useful as modulators of acetylcholine receptors |
12/22/98 |
2/27/01 |
|
6194404 |
Process for the isolation of galanthamine |
8/7/98 |
2/27/01 |
|
6194403 |
Tacrine derivatives for treating Alzheimer's disease |
9/9/99 |
2/27/01 |
|
6191166 |
Methods and compounds for inhibiting .beta.-amyloid peptide release
and/or its synthesis |
11/21/97 |
2/20/01 |
|
6191154 |
Compositions and methods for the treatment of Alzheimer's disease,
central nervous system injury, and inflammatory diseases |
11/27/98 |
2/20/01 |
|
6187785 |
Agent for treating neurodegenerative disorders |
3/25/99 |
2/13/01 |
|
6187756 |
Composition and methods for treatment of neurological disorders
and neurodegenerative diseases |
1/28/00 |
2/13/01 |
|
6184248 |
Compositions and methods for treatment of neurological disorders
and neurodegenerative diseases |
11/8/99 |
2/6/01 |
|
6184236 |
Method of treating a neurodegenerative disease by administering
an aryl-cyclohexylamine derivative |
8/9/99 |
2/6/01 |
|
6180603 |
Method for administering neurologic agents to the brain |
1/8/97 |
1/30/01 |
|
6177472 |
Regulation of alzheimer's disease proteins and uses thereof |
10/27/98 |
1/23/01 |
|
6177077 |
TNT inhibitors for the treatment of neurological disorders |
12/31/99 |
1/23/01 |
|
6172055 |
Apoptosis inhibitors for treating neurodegenerative diseases |
8/14/98 |
1/9/01 |
|
6172043 |
Treatments for neurotoxicity in Alzheimer's disease caused by
.beta. amyloid peptides |
1/9/98 |
1/9/01 |
|
6172041 |
Use of conantokins |
2/10/99 |
1/9/01 |
|
6169115 |
Use of aminoguanidine analogs for the treatment of diseases of
the nervous system |
5/21/99 |
1/2/01 |
|
6166209 |
Piperidine derivatives |
11/20/98 |
12/26/00 |
|
6161044 |
Method and apparatus for treating chronic pain syndromes, tremor,
dementia and related disorders and for inducing electroanesthesia
using high frequency, high intensity transcutaneous electrical
nerve stimulation |
11/23/98 |
12/12/00 |
|
6153652 |
N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical
compositions comprising same, and methods for inhibiting .beta.-amyloid
peptide release and/or its synthesis by use of such compounds |
11/21/97 |
11/28/00 |
|
6150354 |
Compounds for the treatment of Alzheimer's disease |
10/19/93 |
11/21/00 |
|
6140369 |
Benzamides for neurodegenerative disorder treatment |
9/7/99 |
10/31/00 |
|
6136832 |
5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones and methods of
use therefor |
5/19/99 |
10/24/00 |
|
6136548 |
Methods for identifying useful T-PA mutant derivatives for treatment
of vascular hemorrhaging |
9/2/99 |
10/24/00 |
|
6133299 |
Methods for treating neurodegenerative diseases and disorders
using N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas and other
anticonvulsant compounds |
2/25/93 |
10/17/00 |
|
6133259 |
Alkyl, alkenyl and alkynyl chrysamine G derivatives for inhibition
of cell degeneration and toxicity associated with amyloid deposition |
11/9/98 |
10/17/00 |
|
6127370 |
Method for treating alzheimer's disease |
11/8/99 |
10/3/00 |
|
6124456 |
Pyrazolopyridine compound and pharmaceutical use thereof |
1/19/99 |
9/26/00 |
|
6117912 |
Sublingual and buccal administration
of selegiline for treating certain selegiline-responsive diseases
and conditions |
4/28/98 |
9/12/00 |
|
6114365 |
Arylmethyl-carbonylamino-thiazole
derivatives, process for their preparation, and their use as
antitumor agents |
8/12/99 |
9/5/00 |
|
6114334 |
Piperazine derivatives as therapeutic
agents |
12/17/97 |
9/5/00 |
|
6107310 |
Heteroarylcarboxamide derivatives
for treating CNS disorders |
6/16/98 |
8/22/00 |
|
6103754 |
Agent for potentiating nerve growth
factor activity containing 1,2-ethanediol derivative or salt
thereof |
3/9/98 |
8/15/00 |
|
6100269 |
Pharmaceutical compositions for
prevention and treatment of central nervous system disorders |
5/6/99 |
8/8/00 |
|
6087372 |
Method of enhancing cognition with 2-(4-methoxyphenyl)-pyrazolo[4,3-c]quinolin-3-one |
5/25/99 |
7/11/00 |
|
6077852 |
Treatment of central nervous system disorders with selective
estrogen receptor modulators |
4/9/98 |
6/20/00 |
|
6071970 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
6/7/95 |
6/6/00 |
|
6071694 |
Screening method for therapeutic agents against Alzheimer's disease |
6/5/95 |
6/6/00 |
|
6060516 |
N.sup.1 -propargylhydrazines, N.sup.2 -propargylhydrazines and
their analogs for the treatment of depression, anxiety and neurodegeneration |
2/17/98 |
5/9/00 |
|
6060048 |
Method for transplanting cells into the brain and therapeutic
uses therefor |
6/2/95 |
5/9/00 |
|
6056725 |
Therapeutic method for treatment of alzheimer's disease |
8/3/98 |
5/2/00 |
|
6051684 |
Methods of treating neurodegenerative disorders using protease
inhibitors |
5/17/95 |
4/18/00 |
|
6051610 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
2/18/99 |
4/18/00 |
|
6043224 |
Compositions and methods for treatment of neurological disorders
and neurodegenerative diseases |
9/5/97 |
3/28/00 |
|
6037327 |
Specific saccharide compositions and methods for treating Alzheimer's
disease and other amyloidoses |
8/28/98 |
3/14/00 |
|
6034119 |
Agent for potentiating nerve growth factor activity containing
1,2-ethanediol derivative or salt thereof |
2/18/99 |
3/7/00 |
|
6034080 |
Use of Maillard reaction inhibitors for the treatment of amyloidosis-based
disease |
12/4/98 |
3/7/00 |
|
6030984 |
Pyridone compounds useful in treating Alzheimer's disease |
9/28/98 |
2/29/00 |
|
6025395 |
Method of preventing or delaying the onset and progression of
Alzheimer's disease and related disorders |
4/14/97 |
2/15/00 |
|
6022859 |
Inhibitors of .beta.-amyloid toxicity |
11/14/97 |
2/8/00 |
|
6017965 |
Compounds active at a novel site on receptor-operated calcium
channels useful for treatment of neurological disorders and diseases |
12/11/96 |
1/25/00 |
|
6017913 |
Naphthylazo inhibition of amyloidosis |
5/3/99 |
1/25/00 |
|
5990132 |
Polycyclic systems, and derivatives thereof, as neurotransmitter
release enhancers useful in the treatment of cognitive disorders |
6/17/96 |
11/23/99 |
|
5985936 |
Method of preventing and delaying onset of Alzheimer's disease
and composition therefore |
12/18/97 |
11/16/99 |
|
5985930 |
Treatment of neurodegenerative conditions with nimesulide |
4/1/97 |
11/16/99 |
|
5985581 |
Use of presenilin-1 for diagnosis of alzheimers disease |
7/17/97 |
11/16/99 |
|
5981508 |
Facilitation of repair of neural injury with CM101/GBS toxin |
1/29/97 |
11/9/99 |
|
5980933 |
Transdermal formulation of xanomeline |
9/29/97 |
11/9/99 |
|
5980480 |
Method and apparatus for treating adult-onset dementia of the
alzheimer's type |
7/11/96 |
11/9/99 |
|
5977181 |
Therapeutic uses for nitric oxide inhibitors |
11/13/97 |
11/2/99 |
|
5972956 |
Inhibition of amyloidosis by 9-acridinones |
4/29/98 |
10/26/99 |
|
5958964 |
Use of melatonin to prevent cytotoxic effects of amyloid beta
protein |
2/18/97 |
9/28/99 |
|
5958919 |
Treatment of presymptomatic alzheimer's disease to prevent neuronal
degeneration |
9/20/96 |
9/28/99 |
|
5952349 |
Muscarinic antagonists for treating memory loss |
7/8/97 |
9/14/99 |
|
5948800 |
Preventive or therapeutic drug for Alzheimer's disease |
8/4/97 |
9/7/99 |
|
5948763 |
Peptides and pharmaceutical compositions thereof for treatment
of disorders or diseases associated with abnormal protein folding
into amyloid or amyloid-like deposits |
4/10/96 |
9/7/99 |
|
5928882 |
Treatment and prevention of neurodegenerative diseases using
modulators of Fe65 |
10/24/97 |
7/27/99 |
|
5900409 |
Cerebration improver |
11/2/95 |
5/4/99 |
|
5891887 |
Uses of [R-(Z)]-.alpha.-(methoxyimino)-.alpha.-(1-azabicyclo
[2.2.2.] oct-3-yl) |
4/25/97 |
4/6/99 |
|
5891923 |
R-enantiomer of N-propargyl-1-aminoindan for the treatment of
dementia |
6/6/95 |
4/6/99 |
|
5886023 |
Agent for improving dementia |
5/22/95 |
3/23/99 |
|
5880116 |
Use of celastrol to treat alzheimer's disease |
12/13/96 |
3/09/99 |
|
5880256 |
Factor VIIa inhibitors from Kunitz domain proteins |
3/03/95 |
3/09/99 |
|
5877173 |
Preventing neuronal degeneration in Alzheimer's disease |
8/28/96 |
3/2/99 |
|
5876948 |
Screening methods to identify neurotoxin inhibitors |
7/29/91 |
3/2/99 |
|
|