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Antibodies
Antibody Directory
Initial Search
Antigen Class:
-- all --
14-3-3
4E-BP1
4-hydroxy-nonenal
5-HT /serotonin
ABC, ABC transporter
ACC
ACE
Acetylcholine-related
Actin related
ADAM and ADAMTS
Adaptin
Adaptor Protein Complex (AP)
Adenomatus Polyposis Coli /APC
Adenylate cyclase
AFP
AGE and RAGE
Akt and serine/threonine kinases
Alix
Alpha-1-antitrypsin
α-, β-, γ-secretase
AMCase
Amino acids, phosphorylated
AMPAR, NMDAR, GluR1, GluR2
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AMPK
Amyloid-beta related
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AP-2 transcription factor
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ASK
ATPase
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Barrier-to-autointegration factor /BAF
Bassoon
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β-galactosidase
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c-Fos and c-Jun
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Charged multivesicular body protein /CHMP
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DCP
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DJ-1
Dlg/Discs-large
Dlx2
DNA/RNA Oxidative Damage
Dopamine related: DBH, DRD, DDC
Doublecortin
DR6
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Dynamin related protein
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eIF /Eukaryotic initiation factor
ECE
ECT, Lipid Metabolism
EEA1
EGF, EGFr
EGR-1 /Zif268
Elav proteins
Elongation Factors
Endosomes
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FAS-Related
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Futsch
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GFP and RFP
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glucocorticoid receptor /GR
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Go
Golgi matrix/membrane, GM130
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GRKs
GSK-3
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HA and HIS peptides
Hb9
Heat Shock Proteins
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HES
Histone deacetylase (HDAC)
histones
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IFN-γ
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IgG
Insulin Receptor
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IRF
iron metabolism: transferrin, ferroportin, CP
IRS
Islet
JAK2
JNK/SAPK-1/2/3 and MAPK8-10
Ki-67
Kinesin Heavy Chain
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Lamp
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LHX2
LL37 /CAP18
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Matrix Metalloproteinase (MMP)
MeCP2
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Neurexin
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NG2
NGF, NGF-related
NGFR, Trk-A/B
Nieman Pick C1
Nitrotyrosine
Nkx
NOS
Notch, Jagged, Delta
NOX2
NSE
NUMB and NUMBLike
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Olfactory Proteins
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p19
p21 and p27
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PAK
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Presenilins
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proteolipid protein /PLP
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PSD95
PTPs
Rab or Ras related, except Rab3
Rac and Cdc42
RAP
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Retrolinkin
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Rho
Rhodopsin
Ribonucleotide Reductase
Ryanodine receptor
S-100
S6 Kinase
Sestrin
SHP2
SIRT1/Sir2 and SIRT2
SNX
SOCS3/CIS3
SOD
Sodium channel, voltage gated
Somatostatin related
Sortilins
SOS-1
Sox
Spectrins
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SR-BI
Src
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Stat1, Stat3 and related proteins
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Thioredoxin related
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Tip60
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Tom
tPA and PAI-1
TRA-1
Trans-Golgi network /TGN
TRRAP
Tryptophan Hydroxylase
TSG101
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TUC (TOAD/Ulip/CRMP)
Tyrosine Hydroxylase
Tyrosine kinase
UbcH
Ubiquitin
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VEGF and VEGF Receptor
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VGAT
vGluT
von Willebrand factor
Vps35
WNT3
ZO-1
(plus)
Keywords:
any keywords
all keywords
Search Results:
Antigen Class
=SIRT1/Sir2 and SIRT2
Narrow Results
Host:
Method:
Species Reactivity:
Distributor:
-- select --
goat
mouse
rabbit
----------------
all monoclonal
all polyclonal
all kit
-- select --
ELISA
FC
IB
IC
IF
IH
IH(P)
IP
WB
and
-- select --
human
mouse
rat
and
-- select --
Abcam Ltd
ABGENT
Acris Antibodies Gmb
AMS Biotechnology L
AUSTRAL Biologicals
AUTOGEN BIOCLEAR UK
Biolegend, Inc.
BIOMOL Enzo Life Sci
CHEMICON INTERNATION
DELTA BIOLABS, LLC
Epitomics, Inc.
GeneTex
I B L America
I B L Company, Ltd.
Insight Biotechnolog
INTERCHIM
MBL International
Novus Biologicals, I
Orbigen
SANTA CRUZ BIOTECHNO
SIGMA-ALDRICH U.S.
tebu-bio SA
United States Biolog
exclude selected host
-- select --
ELISA
FC
IB
IC
IF
IH
IH(P)
IP
WB
-- select --
human
mouse
rat
1 to 52 of 52 results
Important Notice:
We are striving to include as many companies or products as possible, but we do not make a claim to being comprehensive. We may inadvertently omit specific companies or products due to a lack of information.
Antibodies to SIRT1/Sir2 and SIRT2
From the Manufacturers
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
Sir2/ SIRT1
(E104)
IgG
Epitomics
Cat# 1104-1
immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1
monoclonal rabbit
(liquid, tris-glycine saline, glycerol, azide, BSA)
IC,
IH(P)
, IP, WB
SIRT1;
no
cross-reaction with other sirtuin family members
human
Sir2/ SIRT1
(E54)
IgG
Epitomics
Cat# 1054-1
immunogen = synthetic peptide corresp. to residues near N-terminus and before Ala-rich domain of human Sir2
monoclonal rabbit
(liquid, tris-glycine saline, glycerol, BSA, azide)
FC, IC,
IH(P)
, IP, WB
Sir2/SIRT1
human
Sir2/ SIRT1
(E104)
IgG
Insight Biotechnology
Cat# 1104-1
available in UK and Ireland only; supplied by Epitomics
immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1
monoclonal rabbit
(liquid, tris-glycine saline, glycerol, azide, BSA)
IC,
IH(P)
, IP, WB
SIRT1;
no
cross-reaction with other sirtuin family members
human
Sir2/ SIRT1
(E54)
IgG
Insight Biotechnology
Cat# 1054-1
available in UK and Ireland only; supplied by Epitomics
immunogen = synthetic peptide corresp. to residues near N-terminus and before Ala-rich domain of human Sir2
monoclonal rabbit
(liquid, tris-glycine saline, glycerol, BSA, azide)
FC, IC,
IH(P)
, IP, WB
Sir2/SIRT1
human
Sir2/SIRT1
(10E4)
IgG
Chemicon and Upstate are Millipore
Cat# 04-1091
Immunogen = synthetic peptide corresponding to residues near C-terminus and before Ala-rich domain of human Sir2
monoclonal rabbit
(liquid, Tris-Glycine, saline, BSA, glycrol, azide)
IC,
IH(P)
, IP, WB
recognizes SIRT1(~110 kDa by WB); does not cross-react with other sirtuin family members.
human
Sir2/SIRT1
(poly)
IgG
I B L America
Cat# 18761
supplied by IBL Japan
Immunogen = Synthetic peptides for part of C Terminal of human Sir2/SIRT1 (LEDEPDV PERAGG)
polyclonal rabbit
(affinity purified, BSA, PBS, azide, lyophilized)
IH(P)
, IP, WB
Sir2/SIRT1
human
Sir2/SIRT1
(poly)
IgG
I B L Company, Ltd.
Cat# 18761
also distributed by IBL Hamburg
Immunogen = Synthetic peptides for part of C Terminal of human Sir2/SIRT1 (LEDEPDV PERAGG)
polyclonal rabbit
(purified, BSA, PBS, azide, lyophilized)
IH(P)
, IP, WB
Sir2/SIRT1
human
SIRT1
(E104)
IgG
Abcam
Cat# ab32441
immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1
monoclonal rabbit
(liquid, tris-glycine, BSA, glycerol, azide)
IC,
IH(P)
, IP, WB;
not
FACS
SIRT1;
no
cross reaction with sirtuin family members
human
(
not
mouse or rat; other species not tested)
SIRT1
(E54)
IgG
Abcam
Cat# ab32424
immunogen = synthetic peptide corresponding to residues near N-terminus and before Ala-rich domain of human Sir2.
monoclonal rabbit
(liquid, tris-glycine saline, BSA, glycerol, azide)
FC, IC,
IH(P)
, IP, WB
SIRT1;
no
cross-reaction with other sirtuin family members
human
(
not
mouse or rat)
SIRT1
(poly)
IgG
Abcam
Cat# ab7343
Immunogen = two synthetic peptides, conjugated to KLH, derived from within residues 1 - 50 and 450-610 of human SIRT1
polyclonal rabbit
(liquid, whole antiserum, PBS, BSA, azide)
IP, WB
SIRT1
human
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
SIRT1
(poly)
IgG
Abcam
Cat# ab12193
Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1
polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified)
IF, WB
SIR2
mouse
SIRT1
(poly)
IgG
Abcam
Cat# ab13749
Immunogen = peptide mapping to the C-terminal domain of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide, affinity purified)
WB
SIRT1
human
SIRT1
(poly)
IgG
Abcam
Cat# ab28170
immunogen = synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of mouse SIRT1
polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified)
WB
SIRT1
mouse
(other species not tested)
SIRT1
(poly)
Ig
ABGENT
Cat# AP6240a
Immunogen = synthetic peptide (10-30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled
polyclonal rabbit
(liquid, PBS, azide, Protein G purified)
ELISA
SIRT1
human
SIRT1
(poly)
IgG
Acris Antibodies
Cat# DB083
supplied by Delta Biolabs
Immunogen = peptide mapping to the C-terminal domain of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide, affinity purified)
WB
SIRT1
human
SIRT1
(poly)
Ig
AMS Biotechnology
Cat# AP6240a
supplied by Abgent Europe
Immunogen = synthetic peptide (10-30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled
polyclonal rabbit
(liquid, PBS, azide, Protein G purified)
ELISA
SIRT1
human
SIRT1
(3H2/GH)
IgG
1
Austral Biologicals
Cat# TM-501-55
Immunogen = synthetic peptide corresp. to aa 551-599 of human Sirt1, ovalbumin conj.
monoclonal rabbit
(liquid, IgG fraction, Protein G purified)
ELISA, IB, IP
120 kDa SIRT1
human
SIRT1
(poly)
IgG
Autogen Bioclear
Cat# SC-15404
supplied by Santa Cruz
Immunogen = amino acids 448-747 of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide)
IF, IP, WB
SIRT1
human, rat, mouse
Sirt1
(poly)
Biolegend
634302
immunogen = peptide mapping to the carboxy terminal domain of human SIRT1
polyclonal rabbit
(liquid, affinity purified, PBS, azide, gelatin)
IP, WB
recognizes human SIRT1 protein
human
SIRT1
(poly)
Biomol Enzo Life Sciences
Cat# SA-427
Immunogen = recombinant human SIRT1
polyclonal rabbit
(liquid, immuno-depleted antiserum, PBS)
WB
SIRT1 (recombinant and native).
No
cross-reactivity with recombinant human SIRT2, SIRT3 or SIRT5.
human
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
SIRT1
(kit)
Biomol Enzo Life Sciences
Cat# AK-555
(complete assay system designed to measure the lysyl deacetylase activity of recombinant human SIRT1)
IF
SIRT1, recombinant
SIRT1
(10E4)
IgG,κ
Chemicon and Upstate are Millipore
Cat# 04-1557
Immunogen = His-tagged recombinant protein corresponding to human SIRT1; mouse sequence is 100% identical to immunogen
monoclonal mouse
(liquid, purified, Tris-Glycine, saline, azide)
IC, IH, IP, WB
recognizes SIRT1
human, mouse
(but not mouse in IH.)
SIRT1
(2G1/F7)
IgG
1
Chemicon and Upstate are Millipore
Cat# 05-707.
Suggested replacement, 07-131
References:
Qin, 2006
Immunogen = peptide corresp. to aa 551-599 of human Sirt1
monoclonal mouse
(liquid, PBS, glycrol, azide, Protein G purified)
IP, WB
SIRT1(120kDa by WB). An additional unidentified band was detected (100 kDa).
human
SIRT1
(poly)
IgG
Delta Biolabs
Cat# DB083
Immunogen = peptide mapping to the C-terminal domain of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide, affinity purified)
WB
SIRT1
human
SIRT1
(poly)
IgG
GeneTex
Cat# GTX12193
supplied by Abcam, and listed as anti-SIRT1
Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1
polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified)
IF, WB
SIR2
mouse
SIRT1
(poly)
IgG
GeneTex
Cat# GTX27343
supplied by Abcam
Immunogen = two synthetic peptides, conjugated to KLH, derived from within residues 1 - 50 and 450-610 of human SIRT1
polyclonal rabbit
(liquid, whole antiserum, PBS, BSA, azide)
IP, WB
SIRT1
human
SIRT1
(poly)
IgG
GeneTex
Cat# GTX13749
supplied by Abcam
Immunogen = peptide mapping to the C-terminal domain of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide, affinity purified)
WB
SIRT1
human
SIRT1
(poly)
IgG
Insight Biotechnology
Cat# 14-6769
available in Europe only; supplied by eBioscience
immunogen = peptide mapping to the C-terminal domain of human SIRT1
polyclonal rabbit
(liquid, PBS, gelatin, azide, affinity purified)
WB
SIRT1
human
SIRT1
(poly)
IgG
Insight Biotechnology
Cat# sc-15404
available in UK only; supplied by Santa Cruz
immunogen = aa 448-747 of SIRT1 of human origin
polyclonal rabbit
(PBS, azide, gelatin)
IF, IP, WB
SIRT1
human, rat, mouse
SIRT1
(poly)
IgG
Insight Biotechnology
Cat# sc-19857
available in UK only; supplied by Santa Cruz
immunogen = peptide mapping within an internal region of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, IP, WB
SIRT1
human, rat, mouse
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
SIRT1
(poly)
IgG
Insight Biotechnology
Cat# sc-19858
available in UK only; supplied by Santa Cruz
immunogen = peptide mapping near the C-terminus of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, WB
SIRT1
human
SIRT1
(poly)
IgG
Interchim
Cat# GL1471
supplied by Abcam as ab12193
Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1
polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified)
IF, WB
SIR2
mouse
SIRT1
(poly)
Interchim
Cat# GL1470
supplied by Bioscience Innovations as AP6240A
Immunogen = within aa 646-660
polyclonal rabbit
ELISA
human
SIRT1
(poly)
IgG
MBL International
Cat# CY-P1016
Immunogen = recombinant full length SIRT
polyclonal rabbit
(DEAE purified, phosphate buffer, glycerol)
IP
detects endogenous levels of SIRT1 protein; does not cross-react with type I and II HDAC proteins.
human
SIRT1
(7B7)
IgG
1
,κ
Novus Biologicals
Cat# H00023411-M01
supplied by Abnova
available only in North America
Immunogen = partial recomb. SIRT1 (456 aa. ~ 555 aa.) with GST tag
monoclonal mouse
(liquid, purified IgG, no preservative)
WB
SIRT1
human
(others not tested)
SIRT1
(poly)
IgG
Novus Biologicals
Cat# NB100-2132
Immunogen = peptide mapping to a region between residue 25 and 75 of human SIRT1
polyclonal rabbit
(liquid, TBS, BSA, azide, affinity purified)
IP, WB
Sirt1, nuclear
human
(others not tested)
SIRT1
(poly)
IgG
Novus Biologicals
Cat# NB100-2133
Immunogen = peptide mapping to a region between residue 700 and the C-terminus (residue 747) of human SIRT1
polyclonal rabbit
(liquid, TBS, BSA, azide, affinity purified)
IP, WB
Sirt1, nuclear
human
(others not tested)
SIRT1
(poly)
Novus Biologicals
Cat# H00023411-A01
supplied by Abnova
available only in North America
Immunogen = partial recomb. SIRT1
polyclonal mouse
(liquid, antisera, glycerol, no preservative)
IP, WB
SIRT1
human
(others not tested)
SIRT1
(poly)
Orbigen
Cat# PAB-11096
Immunogen = KLH conjugated synthetic peptide comprised of aa 646 - 660 [PPNRYIFHGAEVYSD] of human SIRT1
polyclonal rabbit
(liquid, PBS, azide, protein-G purified)
ELISA
SIRT1
human
SIRT1
(poly)
IgG
Santa Cruz
Cat# sc-19858
immunogen = peptide mapping near the C-terminus of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, WB
SIRT1
human
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
SIRT1
(poly)
IgG
Santa Cruz
Cat# sc-19857
immunogen = peptide mapping within an internal region of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, IP, WB
SIRT1
human, rat, mouse
SIRT1
(poly)
IgG
Santa Cruz
Cat# sc-15404
immunogen = aa 448-747 of SIRT1 of human origin
polyclonal rabbit
(PBS, azide, gelatin)
IF, IP, WB
SIRT1
human, rat, mouse
SIRT1
(SIR11)
IgG
1
Sigma Aldrich
Cat# S5196
immunogen = synthetic peptide corresp. to aa. 722-737 at the C-terminus of mouse Sir2 with C-terminal added lysine
monoclonal mouse
(liquid, PBS, azide)
ELISA, WB
SIRT1
mouse
SIRT1
(poly)
tebu-bio
Cat# 034SA-427-0100
supplied by Biomol
Immunogen = recombinant human SIRT1
polyclonal rabbit
(liquid, immuno-depleted antiserum, PBS)
WB
SIRT1 (recombinant and native).
No
cross-reactivity with recombinant human SIRT2, SIRT3 or SIRT5.
human
SIRT1
(poly)
IgG
tebu-bio
Cat# 036SC-19858
supplied by Santa Cruz
immunogen = peptide mapping near the C-terminus of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, WB
SIRT1
human
SIRT1
(poly)
IgG
tebu-bio
Cat# 036SC-19857
supplied by Santa Cruz
immunogen = peptide mapping within an internal region of SIRT1 of human origin
polyclonal goat
(PBS, azide, gelatin, affinity purified)
IF, IP, WB
SIRT1
human, rat, mouse
SIRT1
(poly)
IgG
tebu-bio
Cat# 036SC-15404
supplied by Santa Cruz
immunogen = aa 448-747 of SIRT1 of human origin
polyclonal rabbit
(PBS, azide, gelatin)
IF, IP, WB
SIRT1
human, rat, mouse
SIRT1
(kit)
tebu-bio
Cat# 034AK-555-0001
supplied by Biomol
(complete assay system designed to measure the lysyl deacetylase activity of recombinant human SIRT1)
IF
SIRT1, recombinant
SIRT1
(5H24)
IgG
1
US Biological
Cat# S1013-88A2
immunogen = synthetic peptide corresponding to aa551-599 of human Sirt1, ovalbumin-conjugated
monoclonal mouse
(liquid, PBS, glycerol, azide, affinity purified)
IP, WB
Sirt1 (120kDa and unidentified band at 100kDa)
human
SIRT1
(5i88)
IgG
1
US Biological
Cat# S1013-88A1
immunogen = synthetic peptide corresponding to aa 551–599 of human silent information regulator 2 homolog (Sirt1) protein, ovalbumin-conj.
monoclonal mouse
(liquid, PBS, protein G affinity purified)
ELISA, IP, WB
Sirt1 (120kDa)
human
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
SIRT1
(poly)
IgG
US Biological
Cat# S1013-88
immunogen = a mixture of two peptides: 1. G A D R E A A S S P A G E P (aa 22-32) 2. M E N P D L K N V G S S T G E K (aa 595-610), KLH-conjugated; GenBank# NP_036370
polyclonal rabbit
(liquid, serum)
WB
Sirt1
human
SIRT1/Sir2
(poly)
IgG
Chemicon and Upstate are Millipore
Cat# 07-131
Immunogen = His-tagged fusion protein corresponding to amino acids 1-131 of mouse Sir2α
polyclonal rabbit
(liquid, purified, Tris-Glycine, saline, azide, glycerol)
IC, IP, WB
recognizes SIRT1, ~110 kDa
human, mouse
1 to 52 of 52 results
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