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Home: Research: Compendia: Antibodies
 Antibody Directory
Initial Search
Antigen Class:   
(plus) Keywords:   any keywords all keywords
 Search Results: Antigen Class=Presenilins
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Important Notice: We are striving to include as many companies or products as possible, but we do not make a claim to being comprehensive. We may inadvertently omit specific companies or products due to a lack of information.
Antibodies to Presenilin Proteins
From the Laboratories
Antigen
(Clone)
IgG		 Name
(Source)
used in		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
PS-1
(mono)
 PS1-BI.3D7
(Christian Haass,
Adolf Butenandt Institute, University of Munich)
used in paper by Steiner, 2002		 fusion protein, C-terminal (aa 263-407)  monoclonal
 		   N terminus of PS-2  (reference:
Steiner J., et al., J. Biol. Chem 2744:7615-8, l999) 
PS-1
(NT1)
IgG1 		anti-PS1-NT1
(Paul Mathews, New York University, School of Medicine,
Center for Dementia Research)
produced by Covance
Reference: Gu, 2002		 directed against residues 41-49 (RRSLGHPEP) of PS-1  monoclonal mouse
(purified) 		 IP, WB; immunolabeling  recognizes full length PS-1 and the ~28 kDa amino-terminal fragment produced by in vivo proteolysis in L cells overexpressing PS1, but not proteins in mouse L cells overexpressing human PS2. NT1 recognized multiple bands migrating between 28 kDa and 35 kDa from human prefrontal cortex  human, primate (various) 
PS-1
(poly)
 PS1-3027
(Christian Haass,
Adolf Butenandt Institute, University of Munich)
used in paper by Steiner, 2002		 loop domain (aa 263-407) of PS-1  polyclonal
 		 Fusion  loop domain of PS-1  (reference:
Steiner J., et al., J. Biol. Chem 2744:7615-8, l999) 
PS-1
(poly)
 PS1-2953
(Christian Haass,
Adolf Butenandt Institute, University of Munich)		 N-terminus (aa 2-81) of PS-1  polyclonal
 		   N terminus of PS-1  (reference:
Walter J., et al., Proc Natl Acad Sci USA 94:5349-54, l997) 
PS-1
(poly)
 anti-PS1-C
(Hui Zheng, Huffington Center on Aging, Baylor College of Medicine)
used in paper by Xia, 2002		 aa 454-467 of PS1 with glutamate residue added to N terminus to enhance solubility  polyclonal rabbit
 		 WB     (reference:
Culvenor JG, Maher F, ... Beyreuther K, Masters CL., (1997) J Neurosci Res 49:719-731) 
PS-1
(poly)
 B17
(Bart De Strooper,
K.U.Leuven, Belgium)
Reference:
Sato, 2007		 immunogen = peptide p46 (EGDPEAQR RVSKNSKC), situated in the hydrophilic loop domain of PS1
Paper 		 polyclonal rabbit
 		 IP  PS1, hydrophilic loop-specific  human, mouse 
PS-1 loop
(poly)
 anti-αPS1 Loop
(Gopal Thinakaran, Department of Neurobiology, University of Chicago)
References:
Veeraraghavalu, 2010
Yu, 2001
Luo, 2003		 immunogen = aa 320-375 of human PS1  polyclonal rabbit
 		 IH  reacts with epitopes in the hydrophilic loop domain (amino acids 263–407) of human and mouse PS1; no cross reactivity of PS1Loop antiserum with the human PS2 fusion protein  human, mouse
(reference: Thinakaran G., et al., J Biol Chem 272:28415-28422, l997) 
PS-1 NT
(poly)
 PS1NT
(Gopal Thinakaran, Department of Neurobiology, University of Chicago)
References:
Veeraraghavalu, 2010
O'Connor, 2008
Ikeuchi, 2003		 (epitope contains residues 1–65 of the N-terminus of PS1)  polyclonal rabbit
 		 WB  full-length PS1 and NH2-terminal fragment of PS1  (reference: Thinakaran G., et al., Neuron 1996 Jul; 17(1):181-90) 
PS-1 NTF
(poly)
 antibodies 95/23 and 98/1
(Janetta Culvenor,
Department of Pathology, The University of Melbourne, Victoria, Australia)
used in paper by Runz, 2002 		epitope at PS1, aa 1-20  polyclonal rabbit
 		 WB  PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in mouse P19, in CHO-K1 and CHO-APP770 transfected cells, in rat cerebellar granule and hippocampal neurons, and astrocytes. 50 kDa and 30 kDa presumptive cleavage product in WB   
PS-1 NTF
(poly)
 anti-PS1 CTF29414
(C. Elle,
Center for Molecular Biology Heidelberg (ZMBH), University of Heidelberg, INF 282, D-69120 Heidelberg)
used in paper by Runz, 2002		    polyclonal
 		       
Antigen
(Clone)
IgG		 Name
(Source)
used in		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
PS-1 NTF
(poly)
 AB14
(Sam Gandy,
Mount Sinai Alzheimer's Disease Research Center, NYC)
References:
Liu, Y, 2009
Sato, 2007
Luo, 2003
Esler, 2002
Lazarov, 2006		    polyclonal
 		 WB     (reference: Xu H, Gouras G K, ... Greengard P, and Gandy S. Nat. Med. 4,447-451, 1998) 
PS1, C-terminal
(poly)
 4627
(Dr. Dennis Selkoe,
Harvard Univ. Medical School, Boston, MA
Reference:
Sato, 2007		 immunogen = synthetic peptide corresp. to the C-terminal 10 amino acids of PS1 (aa 457-467)
Paper 		 polyclonal rabbit
 		 IP  extreme C-terminal PS1, and PS1 CTF  human, mouse, hamster 
PS1-CTF
(13A11)
 (P. Seubert, Elan Pharmaceuticals)
Reference:
Lazarov, 2006		   monoclonal mouse
 		 WB  Presenilin 1, C-terminal fragments  human 
PS-2
(mono)
 PS1-BIH.F5C
(Christian Haass,
Adolf Butenandt Institute, University of Munich)
used in paper by Steiner, 2002		 fusion protein, C-terminal (aa 297-356)  monoclonal
 		   C terminus of PS-2  (reference:
Steiner J., et al., J. Biol. Chem 2744:7615-8, l999) 
PS-2
(poly)
 PS2-3711
(Christian Haass,
Adolf Butenandt Institute, University of Munich)
used in paper by Steiner, 2002		 loop domain (aa 297-356) of PS-2  polyclonal
 		 Fusion  loop domain of PS-2  (reference:
Steiner J., et al., J. Biol. Chem 2744:7615-8, l999) 
PS-2
(poly)
 PS2-2972
(Christian Haass,
Adolf Butenandt Institute, University of Munich)
used in paper by Steiner, 2002
paper by Esler, 2002		 N terminus of PS-2  polyclonal
 		 Fusion  N terminus of PS-2  (reference:
Walter J., et al., Biochemistry 37:5961-7, l998) 
PS-2
(poly)
 PS2 (GL2)
(Takeshi Iwatsubo, Department of Neuropathology & Neuroscience, Grad. School of Pharmaceutical Sciences, University of Tokyo)
References:
Zhao, 2010
Yu, 2001		 immunogen = GST fused to amino acids 301–361 of human PS2  polyclonal rabbit
 		 IH, WB  detects C-terminus of PS-2  human
(reference paper: Tomita T, Tokuhiro S, Hashimoto T, Aiba K, Saido T C, Maruyama K, Iwatsubo T. J. Biol. Chem 273, 21153-21160, 1998) 
PS-2 CTF
(poly)
 B24.2
(Bart De Strooper,
K.U.Leuven, Belgium)
Paper
Reference:
Zhao, 2010		 immunogen = the peptide KLDPSSQGAL QLPYDPEMEE (amino acids 306–325), coupled to KLH  polyclonal rabbit
(liquid, supernatant) 		 WB  detects C-terminal fragments of PS-2  mouse 
From the Manufacturers
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(APS 11)
IgG1 		Abcam
cat# ab15456		 immunogen = synthetic peptide, H L S N T V R S Q N D N R E, corresp. to aa 21-34 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, IF, IH(P), WB  presenilin 1; no cross reaction with presenilin 2  human, rat, mouse
(cynomoglus monkey, cow, dog from homology) 
Presenilin 1
(APS 18)
IgG1 		Abcam
cat# ab15458		 immunogen = synthetic peptide, S K Y N A E S T E R E S Q D T V A E N D D G, corresp. to aa 313-334 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, azide, protein G purified) 		 ELISA, IF, WB  presenilin 1 (Integral membrane protein. Golgi and endoplasmic reticulum. Bound to Notch1 which is also at the cell surface)  human, rat, mouse
(cynomoglus monkey from homology) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab7297		 immunogen = synthetic peptide corr. to N-terminus aa 14-33 of human presenilin-1  polyclonal goat
(liquid, whole antiserum, no preserves) 		 ELISA, IH(F, P), WB  ~48 kDa Presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
IgG1 		Abcam
cat# ab10281		 immunogen = synthetic peptide: T E L P A P L S Y F N R K C (human) conj. to KLH  polyclonal rabbit
(liquid, whole antiserum, sterile filtered, azide) 		 IP, WB  Presenilin 1  human
(others not tested, expect mouse, rat, cow, macaque) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab11147		 immunogen = synthetic peptide derived from N-terminus of human presenilin-1  polyclonal rabbit
(liquid, whole antiserum, azide) 		 IH(F)  Presenilin 1  monkey, human, hamster
(others not tested) 
Presenilin 1
(poly)
IgY 		Abcam
cat# ab16244		 immunogen = synthetic peptide, K N S K Y N A E S T E R and E A Q R D S H L G P H R, corresp. to aa 311-322 and 342-353 of human Presenilin 1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  Presenilin 1  human, rat, mouse
(others not tested) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab15508		 immunogen = synthetic peptide corresp. to N-terminal region of human presenilin 1  polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified) 		 IH(P)  presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab24748		 immunogen = synthetic peptide, C I L A G E D P E E R G V K L G L G D F I F Y S, corresp. to C- terminal aa 368-390 of human Presenilin 1, conjugated to KLH   polyclonal rabbit
(liquid, affinity purified) 		 IC, IF, IP, WB  Presenilin 1  human
(mouse, rat, cow, cynomolgus monkey, orangutan, and dog expected from homology) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab12272		 immunogen = purified recombinant protein, encompassing C-terminal aa 298-367 of human Presenilin 1  polyclonal rabbit
(liquid, serum, azide) 		 IC, WB  presenilin 1  monkey, human, mouse, hamster
(others not tested) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab12273		 immunogen = synthetic peptide corresp. to N-terminal aa 25-50 of human Presenilin 1, conj. to KLH  polyclonal rabbit
(liquid, serum, azide) 		 IC, WB  Presenilin 1 (detects full-length and N-terminal fragments)  monkey, human
(others not tested) 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
IgG 		Abcam
cat# ab11146		 immunogen = highly purified antigen  polyclonal rabbit
(liquid, serum, azide) 		 IH(F), IP, WB  presenilin 1  monkey, human
(others not tested) 
Presenilin 1
(poly)
IgG 		Abcam
cat# ab38323		 immunogen = synthetic peptide (10-30 aa in length) in the region of aa 370-384 of human Presenilin 1, conj. to KLH  polyclonal rabbit
(liquid, PBS, azide, protein G purified) 		 ELISA, IH(P), WB  presenilin 1  human, mouse
(others not tested) 
Presenilin 1
(poly)
 Abnova Corporation
cat#
H00005663-A01		 immunogen = PSEN1 (AAH11729, 280- 379 a.a) partial recombinant protein with GST tag  polyclonal mouse
(liquid, glycerol) 		 ELISA, WB  Presenilin 1  human 
Presenilin 1
(mono)
 Acris Antibodies
cat# PS12-M
supplied by
A D I		 immunogen = GST-human PS1 fusion protein (aa 21-80)  monoclonal rat
(antiserum, ascites, unpurified) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse
(others not tested) 
Presenilin 1
(APS 11)
IgG1 		Acris Antibodies
cat# SM5161P		 immunogen = synthetic peptide, C-H(21) L S N T V R S Q N D N R E(34) from human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IF, IH(P), WB  Presenilin 1; no cross-reactivity with presenilin 2  monkey, human, rat, mouse 
Presenilin 1
(APS 18)
IgG1 		Acris Antibodies
cat# SM5162P		 immunogen = synthetic peptide, C-S(313) K Y N A E S T E R E S Q D T V A E N D D G(334), from human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IF, IP, WB  Presenilin 1; no cross-reactivity with presenilin 2  monkey, human, rat, mouse 
Presenilin 1
(poly)
IgY 		Acris Antibodies
cat# SP5186P		 immunogen = two synthetic peptides, K(311) N S K Y N A E S T E R(322) and E(342) A Q R D S H L G P H R(353), from human PS1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  Presenilin 1  human, rat, mouse
(others not tested) 
Presenilin 1
(poly)
 Acris Antibodies
cat# SP1373P		   polyclonal rabbit
(liquid, serum, azide) 		 IH(F), IP, WB  Presenilin 1  monkey, human
(others not tested) 
Presenilin 1
(poly)
 Acris Antibodies
cat# RA18020
supplied by Neuromics		 immunogen = peptide corresp. to residues around valine 293 of human PS1  polyclonal rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified) 		 IP, WB  detects endogenous levels of C-terminal frag. of presenilin 1 (~22kDa); detects full length protein (55kDa) to a lesser extent  human, primate (various), rat, mouse 
Presenilin 1
(poly)
 Acris Antibodies
cat# SP1227		 immunogen = peptide at N-terminus (aa 14-33) of human PS1  polyclonal rabbit
(liquid, serum, azide) 		 ELISA, WB  presenilin 1  human 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
 Acris Antibodies
cat# PS13-S
supplied by
A D I		 immunogen = a 20-aa peptide from human Presenilin-1, at the N-terminus, extracellular region  polyclonal goat
(unpurified antiserum) 		 ELISA, IF, IH, IP, WB  Presenilin-1; no cross with PS2 or other known proteins  human
(monkey, lemur, bovine, mouse, rat by homology) 
Presenilin 1
(poly)
 Acris Antibodies
cat# PS11-S
supplied by
A D I		 immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1  polyclonal rabbit
(unpurified antiserum) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse, xenopus 
Presenilin 1
(poly)
IgG 		Acris Antibodies
cat# PS11-A
supplied by
A D I		 immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1  polyclonal rabbit
(affinity purified with PBS, BSA and merthiolate) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse, xenopus 
Presenilin 1
(poly)
IgG 		Acris Antibodies
cat# NB600-674
supplied by Novus		 immunogen = synthetic peptide derived from N-terminus of human presenilin 1  polyclonal rabbit
(liquid, serum, azide) 		 IH(F)  Presenilin 1  monkey, human, hamster
(others not tested) 
Presenilin 1
(poly)
 Acris Antibodies
cat# SP1374P		 immunogen = synthetic peptide derived from N-terminus of human presenilin 1  polyclonal rabbit
(liquid, serum, azide) 		 IH(F)  Presenilin 1  monkey, human, hamster
(others not tested) 
Presenilin 1
(poly)
 Acris Antibodies
cat# GT15027, GT15027X
supplied by Neuromics		 immunogen = recombinant human PS1 N-terminal frag. (1-80 aa)  polyclonal goat
(liquid, affinity purified) 		 ELISA, IH(P), WB  Presenilin 1  human 
Presenilin 1
(poly)
 Acris Antibodies
cat# RA18004
supplied by Neuromics		 immunogen = peptide corresp. to residues surrounding aa 330 of human PS2  polyclonal rabbit
(liquid, HEPES, NaCl, BSA, glycerol, protein A and affinity purified) 		 IC, IH, IP, WB  detects endogenous levels of C-terminal frag. of PS2 (~20 kDa); detects full length protein (54kDa) to a lesser extent; no cross-reaction with PS1  human, rat, mouse 
Presenilin 1
(APS 11)
IgG1 		Axxora
cat# ALX-804-554		 immunogen = synthetic peptide corresp. to aa 21-34 (C-H(21) L S N T V R S Q N D N R E(34) of N-terminal human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, IH(P), WB  Presenilin 1 (~28kDa); no cross with PS2  human, primate (various), rat, mouse 
Presenilin 1
(APS 18)
IgG1 		Axxora
cat# ALX-804-555		 immunogen = synthetic peptide corresp. to aa 313-334, S(313) K Y N A E S T E R E S Q D T V A E N D D G(334), of C-terminal human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, WB  detects C-terminal frag. (~18 kDa) and full length (~46 kDa) presenilin 1; no cross with presenilin 2  human, primate (various), rat, mouse 
Presenilin 1
(poly)
 Axxora
cat# ALX-210-562		 immunogen = two synthetic peptides corresp. to aa 311-322 (K N S K Y N A E S T E R) and aa 342-353 (E A Q R D S H L G P H R) of human PS1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  Presenilin 1 (~66 kDa)  human, rat, mouse 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
 Axxora
cat# SIG-9360
supplied by Signet		 immunogen = synthetic peptide (T E L P A P L S Y F N R K C) conj. to KLH  polyclonal rabbit
(liquid, concentrate) 		 IP, WB  presenilin 1  human 
Presenilin 1
(APS 18)
IgG1 		Euromedex
cat# GTX15458
supplied by GeneTex		 immunogen = synthetic peptide, S K Y N A E S T E R E S Q D T V A E N D D G, corresp. to aa 313-334 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, azide, protein G purified) 		 ELISA, IF, WB  presenilin 1 (Integral membrane protein. Golgi and endoplasmic reticulum. Bound to Notch1 which is also at the cell surface)  human, rat, mouse
(cynomoglus monkey from homology) 
Presenilin 1
(poly)
 Euromedex
cat#
H00005663-A01
supplied by Abnova		 immunogen = PSEN1 (AAH11729, 280~ 379 aa) partial recombinant protein with GST tag  polyclonal mouse
(liquid, glycerol) 		   presenilin 1   
Presenilin 1
(poly)
 Euromedex
cat# GTX74464
supplied by GeneTex		 immunogen = human presenilin 1  polyclonal rabbit
(liquid, azide) 		 ELISA, IH, WB  presenilin 1  monkey, human 
Presenilin 1
(poly)
 Euromedex
cat# GTX74465
supplied by GeneTex		 immunogen = synthetic petide derived from N-terminus of human presenilin-1  polyclonal rabbit
(liquid, azide) 		 IH  presenilin 1  monkey, human, hamster 
Presenilin 1
(poly)
 Euromedex
cat# GTX74212
supplied by GeneTex		 immunogen = N-terminus peptide (aa 14-33) of presenilin-1  polyclonal goat
(liquid) 		 ELISA, IH, WB  presenilin 1  human 
Presenilin 1
(poly)
IgG 		Euromedex
cat# GTX15508
supplied by GeneTex		 immunogen = synthetic peptide corresp. to N-terminal region of human presenilin 1  polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified) 		 IH(P)  presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
 Fisher Scientific
Cat# 5054138
supplied by Chemicon as AB5310		 immunogen = aa 14 -23 of human PS1 conjugated to KLH.  polyclonal rabbit
(serum, liquid, PBS, azide) 		 IC, WB; not IP  Presenilin-1, N-terminus  monkey, human
(Others not tested) 
Presenilin 1
(poly)
 Fisher Scientific
Cat# 5054137
supplied by Chemicon as AB5308
reference
(rabbit Presenil)
Lee, 2002		 immunogen = aa 275-367 of human PS1 fused to C-terminus of maltose binding protein  polyclonal rabbit
(serum, liquid, PBS, azide) 		 IC, IP, WB  Presenilin 1, loop  monkey, human, mouse, hamster 
Presenilin 1
(APS 11)
IgG1 		GeneTex
cat# GTX15456
supplied by Abcam		 immunogen = synthetic peptide, H L S N T V R S Q N D N R E, corresp. to aa 21-34 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, IF, IH(P), WB  presenilin 1; no cross reaction with presenilin 2  human, rat, mouse
(cynomoglus monkey, cow, dog from homology) 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(APS 18)
IgG1 		GeneTex
cat# GTX15458
supplied by Abcam		 immunogen = synthetic peptide, S K Y N A E S T E R E S Q D T V A E N D D G, corresp. to aa 313-334 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, azide, protein G purified) 		 ELISA, IF, WB  presenilin 1 (Integral membrane protein. Golgi and endoplasmic reticulum. Bound to Notch1 which is also at the cell surface)  human, rat, mouse
(cynomoglus monkey from homology) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX15508
supplied by Abcam		 immunogen = synthetic peptide corresp. to N-terminal region of human presenilin 1  polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified) 		 IH(P)  presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX12272
supplied by Abcam		 immunogen = purified recombinant protein, encompassing C-terminal aa 298-367 of human Presenilin 1  polyclonal rabbit
(liquid, serum, azide) 		 IC, WB  presenilin 1  monkey, human, mouse, hamster
(others not tested) 
Presenilin 1
(poly)
IgY 		GeneTex
cat# GTX16244
supplied by Abcam		 immunogen = synthetic peptide, K N S K Y N A E S T E R and E A Q R D S H L G P H R, corresp. to aa 311-322 and 342-353 of human Presenilin 1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  presenilin 1  human, rat, mouse
(others not tested) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX11146
supplied by Abcam		 immunogen = highly purified antigen  polyclonal rabbit
(liquid, serum, azide) 		 IH(F), IP, WB  presenilin 1  monkey, human
(others not tested) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX12273
supplied by Abcam		 immunogen = synthetic peptide corresp. to N-terminal aa 25-50 of human Presenilin 1, conj. to KLH  polyclonal rabbit
(liquid, serum, azide) 		 IC, WB  Presenilin 1 (detects full-length and N-terminal fragments)  monkey, human
(others not tested) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX11147
supplied by Abcam		 immunogen = synthetic peptide derived from N-terminus of human presenilin-1  polyclonal rabbit
(liquid, whole antiserum, azide) 		 IH(F)  Presenilin 1  monkey, human, hamster
(others not tested) 
Presenilin 1
(poly)
IgG1 		GeneTex
cat# GTX10281
supplied by Abcam		 immunogen = synthetic peptide (T E L P A P L S Y F N R K C) of human presenilin 1, conj. to KLH  polyclonal rabbit
(liquid, whole antiserum, sterile filtered, azide) 		 IP, WB  Presenilin 1  human
(others not tested, expect mouse, rat, cow, macaque) 
Presenilin 1
(poly)
IgG 		GeneTex
cat# GTX27297
supplied by Abcam		 immunogen = synthetic peptide corr. to N-terminus aa 14-33 of human presenilin-1  polyclonal goat
(liquid, whole antiserum, no preserves) 		 ELISA, IH(F, P), WB  ~48 kDa Presinilin 1  human
(others not tested) 
Presenilin 1
(poly)
 GeneTex
cat# GTX74212		 immunogen = N-terminus peptide (aa 14-33) of presenilin-1  polyclonal goat
(liquid) 		 ELISA, IH, WB  presenilin 1  human 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
 GeneTex
cat# GTX74464		 immunogen = human presenilin 1  polyclonal rabbit
(liquid, azide) 		 ELISA, IH, WB  presenilin 1  monkey, human 
Presenilin 1
(poly)
 GeneTex
cat# GTX74465		 immunogen = synthetic petide derived from N-terminus of human presenilin-1  polyclonal rabbit
(liquid, azide) 		 IH  presenilin 1  monkey, human, hamster 
Presenilin 1
(poly)
 Insight Biotechnology
cat# PS13-S
supplied by Acris,
in UK and Ireland only		 immunogen = a 20-aa peptide from human Presenilin-1, at the N-terminus, extracellular region  polyclonal goat
(unpurified antiserum) 		 ELISA, IF, IH, IP, WB  Presenilin-1; no cross with PS2 or other known proteins  human
(monkey, lemur, bovine, mouse, rat by homology) 
Presenilin 1
(poly)
 Insight Biotechnology
cat# SP1227
supplied by Acris,
in UK and Ireland only		 immunogen = peptide at N-terminus (aa 14-33) of human PS1  polyclonal rabbit
(liquid, serum, azide) 		 ELISA, WB  presenilin 1  human 
Presenilin 1
(poly)
 Insight Biotechnology
cat# SP1373P
supplied by Acris,
in UK and Ireland only		   polyclonal rabbit
(liquid, serum, azide) 		 IH(F), IP, WB  presenilin 1  monkey, human
(others not tested) 
Presenilin 1
(mono)
 Li Starfish
cat# A-PS12-M
supplied by Acris		 immunogen = GST-human PS1 fusion protein (aa 21-80)  monoclonal rat
(antiserum, ascites, unpurified) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse
(others not tested) 
Presenilin 1
(APS 11)
IgG1 		Li Starfish
cat# A-SM5161P
supplied by Acris		 immunogen = synthetic peptide, C-H(21) L S N T V R S Q N D N R E(34) from human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IF, IH(P), WB  Presenilin 1; no cross-reactivity with presenilin 2  monkey, human, rat, mouse 
Presenilin 1
(APS 18)
IgG1 		Li Starfish
cat# A-SM5162P
supplied by Acris		 immunogen = synthetic peptide, C-S(313) K Y N A E S T E R E S Q D T V A E N D D G(334), from human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IF, IP, WB  Presenilin 1; no cross-reactivity with presenilin 2  monkey, human, rat, mouse 
Presenilin 1
(poly)
IgY 		Li Starfish
cat# A-SP5186P
supplied by Acris		 immunogen = two synthetic peptides, K(311) N S K Y N A E S T E R(322) and E(342) A Q R D S H L G P H R(353), from human PS1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  Presenilin 1  human, rat, mouse
(others not tested) 
Presenilin 1
(poly)
 Li Starfish
cat# A-SP1373P
supplied by Acris		   polyclonal rabbit
(liquid, serum, azide) 		 IH(F), IP, WB  Presenilin 1  monkey, human
(others not tested) 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
 Li Starfish
cat# A-SP1227
supplied by Acris		 immunogen = peptide at N-terminus (aa 14-33) of human PS1  polyclonal rabbit
(liquid, serum, azide) 		 ELISA, WB  presenilin 1  human 
Presenilin 1
(poly)
 Li Starfish
cat# A-PS13-S
supplied by
Acris		 immunogen = a 20-aa peptide from human Presenilin-1, at the N-terminus, extracellular region  polyclonal goat
(unpurified antiserum) 		 ELISA, IF, IH, IP, WB  Presenilin-1; no cross with PS2 or other known proteins  human
(monkey, lemur, bovine, mouse, rat by homology) 
Presenilin 1
(poly)
 Li Starfish
cat# A-PS11-S
supplied by
Acris		 immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1  polyclonal rabbit
(unpurified antiserum) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse, xenopus 
Presenilin 1
(poly)
IgG 		Li Starfish
cat# A-PS11-A
supplied by
Acris		 immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1  polyclonal rabbit
(affinity purified with PBS, BSA and merthiolate) 		 ELISA, IF, IH, IP, WB  Presenilin-1  human, rat, mouse, xenopus 
Presenilin 1
(poly)
 Neuromics
cat# RA18020		 immunogen = peptide corresponding to residues around valine 293 of human presenilin 1  polyclonal rabbit
(liquid, HEPES, BSA, glycerol) 		 IP, WB  Presenilin-1  human, primate (various), rat, mouse 
Presenilin 1
(poly)
 Neuromics
cat# GT15027		 immunogen = recomb. human Presenilin-1, N-terminal fragment (aa 1-80)  polyclonal goat
(liquid, affinity purified) 		 ELISA, IH(P), WB  Presenilin-1  human 
Presenilin 1
(APS 11)
IgG1 		Novus Biologicals
cat# NB 300-749		 immunogen = synthetic peptide: HLSNTVR SQNDNRE, corresponding to amino acids 21-34 of Human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, BSA, azide) 		 ELISA, IH, WB  ~28 kDa protein representing PS1 N-terminus cleavage product; no cross with PS2  human, primate (various), rat, mouse
(expect cow, dog, Cynomolgus monkey) 
Presenilin 1
(APS 18)
IgG1 		Novus Biologicals
Cat# NB100-74510		 immunogen = synthetic peptide, S K Y N A E S T E R E S Q D T V A E N D D G, corresp. to aa 313-334 of human Presenilin 1 with N-terminally added cysteine  monoclonal mouse
(liquid, PBS, azide, protein G purified) 		 ELISA, IF, IH, WB  presenilin 1 (Integral membrane protein. Golgi and endoplasmic reticulum. Bound to Notch1 which is also at the cell surface)  human, primate (various), rat, mouse 
Presenilin 1
(EP1998Y)
IgG 		Novus Biologicals
Cat# NB110-66667		 immunogen = synthetic peptide corresp. to residues NTF subunit of Presenilin-1 protein  monoclonal rabbit
(liquid) 		 FC, WB  reacts to residues NTF subunit of Presenilin-1 protein  human, rat, mouse
(others not tested) 
Presenilin 1
(EP2000Y)
IgG 		Novus Biologicals
Cat# NB110-59959		 immunogen = synthetic peptide corresponding to residues in human Presenilin 1  monoclonal rabbit
(liquid) 		 FC, IC, IH, IP, WB  ~18 kDa Presenilin 1  human, rat, mouse
(others not tested) 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
IgG 		Novus Biologicals
Cat# NB100-78570		 immunogen = modified peptide  polyclonal rabbit
(liquid, antisera, PBS, azide, affinity purified) 		 IF  Presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
IgG 		Novus Biologicals
Cat# NB120-15508		 immunogen = synthetic peptide corresp. to N-terminal region of human presenilin 1  polyclonal rabbit
(liquid, PBS, BSA, azide, affinity purified) 		 IH(P)  presenilin 1  human
(others not tested) 
Presenilin 1
(poly)
 Novus Biologicals
cat#
H00005663-A01
supplied by Abnova		 immunogen = PSEN1 partial recombinant protein with GST tag(AAH11729, 280- 379 aa)  polyclonal mouse
(liquid, glycerol) 		 ELISA, WB  presenilin 1  human 
Presenilin 1
(poly)
IgG 		Novus Biologicals
cat# NB 600-674		 immunogen = synthetic peptide derived from N-terminus of human presenilin-1  polyclonal rabbit
(liquid, serum, azide) 		 IH(F)  presenilin 1  monkey, human, hamster
(others not tested) 
Presenilin 1
(poly)
IgG 		Novus Biologicals
Cat# NB100-91935		 immunogen = modified peptide  polyclonal rabbit
(liquid, antisera, PBS, azide, affinity purified) 		 IH, WB  detects endogenous levels of Presenilin 1 protein  human
(others not tested) 
Presenilin 1
(poly)
IgY 		ProSci
cat# XG-1601		 immunogen = two peptides from human presenilin 1, mixed  polyclonal chicken
 		 WB  presenilin 1  human, rat, mouse
(others not tested) 
Presenilin 1
(poly)
 RDI /Fitzgerald
Cat# PRESEN1abG		 aa 14 -33 of the N terminus of the human PS-1  polyclonal goat
 		 ELISA, IH(F, P)  residues 14 -33 on the N- terminus of presenilin-1   
Presenilin 1
(APS 11)
IgG1 		Vinci Biochem
cat# ALX-804-554
supplied by Alexis		 immunogen = synthetic peptide corresp. to aa 21-34 (C-H(21) L S N T V R S Q N D N R E(34) of N-terminal human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, IH(P), WB  Presenilin 1 (~28kDa); no cross with PS2  human, primate (various), rat, mouse 
Presenilin 1
(APS 18)
IgG1 		Vinci Biochem
cat# ALX-804-555
supplied by Alexis		 immunogen = synthetic peptide corresp. to aa 313-334, S(313) K Y N A E S T E R E S Q D T V A E N D D G(334), of C-terminal human PS1  monoclonal mouse
(liquid, PBS, BSA, azide, protein G purified) 		 ELISA, IC, WB  detects C-terminal frag. (~18 kDa) and full length (~46 kDa) presenilin 1; no cross with presenilin 2  human, primate (various), rat, mouse 
Presenilin 1
(poly)
 Vinci Biochem
cat# ALX-210-562
supplied by Alexis		 immunogen = two synthetic peptides corresp. to aa 311-322 (K N S K Y N A E S T E R) and aa 342-353 (E A Q R D S H L G P H R) of human PS1  polyclonal chicken
(liquid, PBS, BSA, azide, PEG purified) 		 WB  Presenilin 1 (~66 kDa)  human, rat, mouse 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
Presenilin 1
(poly)
 Vinci Biochem
cat# SIG-9360
supplied by Alexis		 immunogen = synthetic peptide (T E L P A P L S Y F N R K C) conj. to KLH  polyclonal rabbit
(liquid, concentrate) 		 IP, WB  presenilin 1  human 
Presenilin 1
(poly)
 VWR International, Inc.
Cat# 100169-650
supplied by Chemicon as AB5308		 aa 275-367 of human PS1 fused to C-terminus of maltose binding protein  polyclonal rabbit
(serum, liquid, PBS, azide) 		 IC, IP, WB  Presenilin 1, loop  monkey, human, mouse, hamster 
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