|
Antibodies to COX-1, COX-2 and COX-3
|
| From the Manufacturers
|
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX (poly)
|
Anawa
Cat # BT200-0127 supplied by Biotrend |
|
polyclonal rabbit (antiserum) |
ELISA, WB |
COX |
|
COX (kit)
|
Anawa
Cat # 9007-003 supplied by Biotrend |
|
(detection kit) |
ELISA |
COX |
|
COX (kit)
|
Anawa
Cat # 907-011 supplied by Biotrend |
|
(detection kit) |
ELISA |
COX |
|
COX (poly) IgG
|
Axxora
Cat # ALX-210-709 |
immunogen = purified sheep seminal vesicle COX-1 |
polyclonal rabbit (serum, lyophilized) |
WB |
COX-1 and COX-2 |
rat, mouse, sheep |
COX (poly)
|
Biotrend
Cat# BT200-0127 |
|
polyclonal rabbit (antiserum) |
ELISA, WB |
COX |
|
COX (kit)
|
Biotrend
Cat# 907-003 |
|
(detection kit) |
ELISA |
COX |
|
COX (kit)
|
Biotrend
Cat# 907-011 |
|
(detection kit) |
ELISA |
COX |
|
COX (poly) IgG
|
Cayman Chemical
Cat# 160103 |
immunogen = purified sheep seminal vesicular COX-1 |
polyclonal rabbit (IgG, tris, glycerol, azide) |
IH, WB |
COX-1 and COX-2 |
rat, mouse, sheep (expect bovine and canine) |
COX (kit)
|
Cayman Chemical
Cat# 760151 |
ovine COX1 and COX2 enzymes |
(Activity Assay peroxidase assay, colorimetric, TMPD) |
FC |
COX-1 and COX-2 activity in cell lysates, tissue homogenates, enzyme preparations |
|
COX (poly) IgG
|
SPI bio
cat# 160103 supplied by Cayman Chemical datasheet |
immunogen = purified sheep seminal vesicular COX-1 |
polyclonal rabbit (IgG, lyophilized) |
IB, IH |
COX-1 and COX-2 |
mouse, sheep (not rat) |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX (kit)
|
SPI bio
cat# 760151 supplied by Cayman Chemical datasheet |
ovine COX1 and COX2 enzymes |
(Activity Assay peroxidase assay, colorimetric, TMPD) |
FC |
COX-1 and COX-2 activity in cell lysates, tissue homogenates, enzyme preparations |
|
COX (poly)
|
Takara Bio Inc.
Cat# M165 |
immunogen = Ovine COX |
polyclonal rabbit (lyophilized) |
WB |
COX |
mouse (not rat) |
COX (kit)
|
Vinci Biochem
Cat# 760151 supplied by Cayman |
ovine COX1 and COX2 enzymes |
(Activity Assay peroxidase assay, colorimetric, TMPD) |
FC |
COX-1 and COX-2 activity in cell lysates, tissue homogenates, enzyme preparations |
|
COX /PGH Synthase (poly) IgG
|
Oxford Biomedical Research, Inc.
cat# PG-19 |
|
polyclonal goat (antiserum, azide) |
IA, IH, WB |
detects COX /PGH Synthase |
rodent (various), ovine, mammal (various) |
COX inhibitors (kit)
|
Cayman Chemical
Cat# 560101 |
|
(Screening Assay measures PGF2a production, broadly specific antibody) |
ELISA |
COX-1 and COX-2 inhibitors |
ovine |
COX inhibitors (kit)
|
Cayman Chemical
Cat# 560131 |
|
(Screening Assay measures PGF2a production, broadly specific antibody) |
ELISA |
COX-1 and COX-2 inhibitors |
human, ovine |
COX inhibitors (kit)
|
Cayman Chemical
Cat# 760111 |
ovine COX1 and COX2 enzymes |
(Screening Assay colorimetric substrate, arachidonic acid, assay buffer, KH, heme) |
IS |
COX-1 and COX-2 inhibitors |
ovine |
COX inhibitors (kit)
|
SPI bio
cat# 560101 supplied by Cayman Chemical datasheet |
|
(Screening Assay measures PGF2a production, broadly specific antibody) |
ELISA |
COX-1 and COX-2 inhibitors |
ovine |
COX inhibitors (kit)
|
SPI bio
cat# 560131 supplied by Cayman Chemical datasheet |
|
(Screening Assay measures PGF2a production, broadly specific antibody) |
ELISA |
COX-1 and COX-2 inhibitors |
human, ovine |
COX inhibitors (kit)
|
Vinci Biochem
Cat# 560131 supplied by Cayman |
|
(Screening Assay measures PGF2a production, broadly specific antibody) |
ELISA |
COX-1 and COX-2 inhibitors |
human, ovine |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX inhibitors (kit)
|
Vinci Biochem
Cat# 760101 supplied by Cayman Chemical |
ovine COX1 and COX2 enzymes |
(Screening Assay chemi luminescent substrate, arachidonic acid, assay buffer, KH, heme) |
FC |
COX-1 and COX-2 inhibitors |
ovine |
COX1 (mono)
|
Anawa
Cat # BT200-0129 supplied by Biotrend |
|
monoclonal mouse (ascites) |
ELISA, WB |
COX1 |
sheep |
COX1 (mono)
|
Anawa
Cat # BT200-0130 supplied by Biotrend |
|
monoclonal mouse (ascites) |
WB |
COX-2 |
human |
COX1 (Cyo-1) IgG2b
|
Anawa
Cat # BT200-0128 supplied by Biotrend |
|
monoclonal mouse (culture supernate) |
ELISA, IH(P) |
COX1 |
sheep |
COX1 (mono)
|
Biotrend
Cat# BT200-0129 |
|
monoclonal mouse (ascites) |
ELISA, WB |
COX1 |
sheep |
COX1 (mono)
|
Biotrend
Cat# BT200-0130 |
|
monoclonal mouse (ascites) |
WB |
COX-2 |
human |
COX1 (Cyo-1) IgG2b
|
Biotrend
Cat# BT200-0128 |
|
monoclonal mouse (culture supernate) |
ELISA, IH(P) |
COX1 |
sheep |
COX1 (poly)
|
AbD Serotec
Cat# 0200-0126 |
immunogen = ovine native |
polyclonal goat (liquid, neat serum, azide) |
ELISA, WB |
COX-1; moderate reactivity with COX-2 in most mammalian species but negligible reactivity in chicken |
rat, mouse, sheep (expect most mammals, but reacts weakly with chicken) |
COX-1 (12E12) IgM
|
Abcam
Cat# ab10938 |
immunogen = prokaryotic recomb. protein corr. to 120 aa of the N-terminus of human COX-1 |
monoclonal mouse (liquid, supernate, azide) |
IH |
COX-1, cytoplasmic |
human (others not tested) |
COX-1 (5F6/F4) IgG1κ
|
Abcam
Cat# ab695 |
immunogen = preparation of intracellular proteins of the human cell line HL60 |
monoclonal mouse (liquid, affinity purified, PBS, azide) |
ELISA, WB |
COX-1, no cross-reactivity to COX-2 |
human, mouse (others not tested) |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (AS70) IgG
|
Abcam
Cat# ab16116 |
immunogen = information is considered to be commerically sensitive |
monoclonal mouse (liquid, PBS, azide) |
EIA |
COX1 |
human (others not tested) |
COX-1 (COX111) IgG2b, κ
|
Abcam
Cat# ab38761 |
immunogen = ram testis
|
monoclonal mouse (liquid, PBS, azide, protein A purified) |
ELISA, IC, IF, IH(F, P), WB |
Cox-1 |
human, rat, mouse, sheep |
COX-1 (CYO-1) IgG2b
|
Abcam
Cat# ab22696 |
immunogen =
full length protein (cow); bovine Cox-1
|
monoclonal mouse (liquid, supernatant, azide) |
IH(F) |
reacts with Prostaglandin H Synthase-1 (PGHS-1, Cox-1). |
human, rat, sheep, cow (not guinea pig, rabbit, mouse or dog) |
COX-1 (poly) IgG
|
Abcam
Cat# ab2338 |
immunogen = peptide with sequence Q D D G P A V E R P S T E L, from C-terminus of the protein sequence |
polyclonal goat (liquid, affinity purified, BSA, Tris, azide) |
WB |
both isoforms of the protein |
human (others not tested) |
COX-1 (poly) IgG
|
Abcam
Cat# ab22720 |
immunogen =
full length native
purified Sheep Cox-1 protein
|
polyclonal goat (liquid, whole serum, azide) |
IH(P), WB |
reacts with Prostaglandin H Synthase-1 (PGHS-1, Cox-1). |
human, rat, mouse, sheep (others not tested) |
COX-1 (poly) IgG
|
Abcam
Cat# ab18820 |
immunogen =
synthetic peptide corresp. to aa around residue 586 of mouse COX1
|
polyclonal rabbit (liquid, PBS, BSA, glycerol, azide, affinity purified) |
IP, WB |
Cox-1; not cox-2 |
mouse (expect human, rat) |
COX-1 (poly) IgG
|
Abcam
Cat# ab23858 |
immunogen = purified
full length native protein (sheep)
|
polyclonal rabbit (liquid, whole serum, azide) |
ELISA, WB |
Cox-1 |
sheep, mammal (various) (weakly with PGHS from rodents) |
COX-1 (poly) IgG
|
Abcam
Cat# ab52037 |
immunogen =
synthetic peptide corresp. to C-terminus of human COX1
|
polyclonal rabbit (liquid, PBS, BSA, azide, protein A purified) |
IH(P) |
Cox-1 |
human |
COX-1 (poly) IgG
|
Abcam
Cat# ab52106 |
immunogen =
synthetic peptide corresp. to C-terminus of human COX1
|
polyclonal rabbit (liquid, azide; prediluted) |
IH(P) |
Cox-1 |
human |
COX-1 (poly) IgG
|
Abcam
Cat# ab52657 |
immunogen =
full length mouse protein |
polyclonal mouse (liquid, whole antiserum, glycerol, no preservative) |
WB |
Cox-1 |
mouse |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly) IgG
|
Abcam
Cat# ab23668 |
immunogen =
synthetic peptide, P E F D L S R Y G F G L M Q P E, corresp. to aa 475-490 of mouse Cox-1 |
polyclonal rabbit (liquid, PBS, BSA,TBS, glycerol, azide, affinity purified) |
IC, IH(F, P), WB |
Cox-1 |
human, rat, mouse, sheep, cow |
COX-1 (mono)
|
Accurate
Cat # OBRP G22 |
|
monoclonal mouse |
|
COX-1 |
human, rabbit, sheep, bovine |
COX-1 (mono)
|
Accurate
Cat # OBRP G21 |
|
monoclonal mouse |
|
COX-1 |
human, rat, sheep, bovine |
COX-1 (poly)
|
Accurate
Cat # OBRP G16 |
|
polyclonal rabbit |
|
native and recomb. COX-1, no cross reaction with COX-2 |
|
COX-1 (poly)
|
Accurate
Cat # OBRP G19 |
|
polyclonal goat |
|
COX-1 |
rodent (various), sheep, mammal (various) |
COX-1 (poly)
|
Accurate
Cat # OBRP G20 |
|
polyclonal rabbit |
|
COX-1; slight cross reaction with COX-2 |
sheep, mammal (various) (not rodents) |
COX-1 (12E12) IgM
|
Acris Antibodies
Cat# DM412 |
immunogen = prokaryotic recomb. protein corr. to 120 aa of the N-terminus of human COX-1 |
monoclonal mouse (liquid, supernate, azide) |
IH(F, P) |
COX-1, cytoplasmic |
human (others not tested) |
COX-1 (AS70) IgG1
|
Acris Antibodies
Cat# MC-453 supplied by Kamiya |
|
monoclonal mouse (purified, PBS, azide) |
ELISA |
COX-1 |
human |
COX-1 (COX14-M) IgG2b
|
Acris Antibodies
Cat# COX14-M Cat# COX14-C, pos. control supplied by ADI |
immunogen = purified ovine cox-1 protein |
monoclonal mouse (protein A/G purified, ascites; Ig in PBS and gelatin, or lyophilized) |
ELISA, WB |
COX-1 |
human, rat, mouse, ovine |
COX-1 (Cyo-1) IgG2b
|
Acris Antibodies
Cat# BM937 |
immunogen = purified COX-1 (PGHS-1) from sheep |
monoclonal mouse (liquid, supernatant, azide) |
ELISA, IH(P); not WB |
COX-1 |
human, rat, sheep, bovine (not guinea pig, rabbit, mouse or dog) |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly) IgG
|
Acris Antibodies
Cat# COX11-A and COX11-C, pos. control supplied by ADI |
immunogen = ram seminal vesicles |
polyclonal rabbit (purified, thimerisol or merthiolate, solution or lyophilized) |
ELISA, WB |
COX-1, cross reaction with COX-2 not observed |
human, rat, mouse, sheep, ram |
COX-1 (poly)
|
Acris Antibodies
Cat# EB05285 supplied by Everest Biotech Ltd |
immunogen = peptide with sequence C-Q D D G P A V E R P S T E L, from C terminus of the protein sequence |
polyclonal goat (liquid, affinity purified, BSA, Tris saline, azide) |
WB |
both human isoforms of the COX-1 protein; ~ 65-70kDa bands |
human |
COX-1 (poly)
|
Acris Antibodies
Cat# AP00117PU-N |
immunogen = synthetic peptide corresp. to residues surrounding aa 586 of mouse Cox-1 |
polyclonal rabbit (liquid, affinity purified, PBS, BSA, glycerol, azide) |
IH, IP, WB |
COX-1; no cross reaction with COX-2 |
human, rat, mouse (other species not tested) |
COX-1 (poly)
|
Acris Antibodies
Cat# BP051 |
immunogen = purified COX-1 (PGHS-1) from sheep |
polyclonal rabbit (liquid, serum, azide) |
ELISA, WB |
COX-1; minimal cross reaction with COX-2 |
sheep, mammal (various) (not rat Cox-1, not rh chicken Cox-2) |
COX-1 (COX14-M) IgG2b
|
A D I
Cat# COX14-M Cat# COX14-C, pos. control |
immunogen = purified ovine cox-1 protein |
monoclonal mouse (protein A/G purified, ascites; Ig in PBS and gelatin, or lyophilized) |
ELISA, WB |
COX-1 |
human, rat, mouse, ovine |
COX-1 (poly) IgG
|
A D I
Cat# COX11-A Cat# COX11-C, pos. control |
immunogen = ram seminal vesicles |
polyclonal rabbit (purified, thimerisol or merthiolate, solution or lyophilized) |
ELISA, WB |
COX-1, cross reaction with COX-2 not observed |
human, rat, mouse, sheep, ram |
COX-1 (mono)
|
Anawa
Cat # COX13-M supplied by Biotrend |
|
monoclonal mouse (Ig fraction) |
|
COX-1 |
human |
COX-1 (mono)
|
Anawa
Cat # COX14-M supplied by Biotrend |
|
monoclonal mouse (Ig fraction) |
|
COX-1 |
sheep |
COX-1 (poly)
|
Anawa
Cat # 905-064 supplied by Biotrend |
|
polyclonal rabbit (Ig fraction, affinity purified) |
|
COX-1 |
human |
COX-1 (poly)
|
Anawa
Cat # 905-067 supplied by Biotrend |
|
polyclonal rabbit (Ig fraction, affinity purified) |
|
COX-1 |
rat |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly)
|
Anawa
Cat # COX11-A supplied by Biotrend |
|
polyclonal rabbit (Ig fraction) |
|
COX-1 |
sheep |
COX-1 (poly)
|
Anawa
Cat # COX12-A supplied by Biotrend |
|
polyclonal goat (Ig fraction) |
|
COX-1 |
human |
COX-1 (mono) IgG1, κ
|
Ab Solutions
Cat # AS70-P |
immunogen = human Cox-1 |
monoclonal mouse (liquid, PBS, azide, protein A purified) |
ELISA, WB |
COX-1; no cross with Cox-2 in ELISA |
human |
COX-1 (mono) IgG1, κ
|
Ab Solutions
Cat #AS72-P |
immunogen = human recombinant Cox-1 |
monoclonal mouse (liquid, PBS, azide, protein A purified) |
ELISA, WB |
COX-1; no cross with Cox-2 |
human |
COX-1 (mono) IgG1κ
|
Ab Solutions
Cat# AS71-P |
immunogen = human recombinant COX-1 |
monoclonal mouse (liquid, protein-A purified, Dulbecco's PBS, azide) |
ELISA, WB |
detects COX-1; Does
not react with human COX-2
by ELISA |
human |
COX-1 (AS70) IgG1
|
Assay Designs is Enzo Life Sciences
Cat # COX-010E |
immunogen = recombinant human cyclooxygenase-1 |
monoclonal mouse (liquid, PBS, azide, purified) |
ELISA; EIA |
COX-1 (~68-70kDa) |
human |
COX-1 (mono) IgG2b
|
Autogen Bioclear
Cat# SC-19998 Cat# SC-19998PE supplied by SantaCruz
|
immunogen = Cox-1 from purified sheep seminal vesicles |
monoclonal mouse (liquid, purified, PBS, azide, gelatin) |
FC, IP, WB |
COX-1; no cross with COX-2 |
human, rat, mouse |
COX-1 (mono) IgG1
|
Autogen Bioclear
Cat# SC-52757 Cat# SC-52757PE supplied by SantaCruz
|
immunogen = human Cox-1 |
monoclonal mouse (liquid, PBS, azide, gelatin) |
ELISA |
COX-1 |
human |
COX-1 (mono) IgG1
|
Autogen Bioclear
Cat# SC-52971 Cat# SC-52971PE supplied by Santa Cruz
|
immunogen = human Cox-1 |
monoclonal mouse (liquid, PBS, azide, gelatin) |
WB |
COX-1; no cross with with Cox-2 |
human, mouse |
COX-1 (COX14-M) IgG2b
|
Autogen Bioclear
Cat# COX14-M Cat# COX14-C, pos. control supplied by ADI |
immunogen = purified ovine cox-1 protein |
monoclonal mouse (protein A/G purified, ascites; Ig in PBS and gelatin, or lyophilized) |
ELISA, WB |
COX-1 |
human, rat, mouse, ovine |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly) IgG
|
Autogen Bioclear
Cat# SC-1752 Cat# SC-1752AC (agarose conj) Cat# SC-1752PE (phycoerythrin) supplied by SantaCruz |
immunogen = epitope mapping at the C-terminus of human Cox-1 |
polyclonal goat (liquid, affinity purified, PBS, azide, gelatin) |
FC, IF, IH, IP, WB |
COX-1 |
human, rat, mouse |
COX-1 (poly) IgG
|
Autogen Bioclear
Cat# SC-1754 conjugates: Cat# SC-1754AC (agarose), SC-1754FITC, SC-1754HRPC, SC-1754TRITC SC-1754PE SC-1754 AF405, 488 or 647 (AlexaFluor) supplied by SantaCruz |
immunogen epitope mapping at the C-terminus of mouse Cox-1 |
polyclonal goat (liquid, affinity purified, PBS, azide, gelatin) |
FC, IF, IH(F, P), IP, WB |
COX-1 |
rat, mouse |
COX-1 (poly) IgG
|
Autogen Bioclear
Cat# SC-7950 Cat# SC-7950PE supplied by SantaCruz |
immunogen = aa 63-124 human Cox-1 |
polyclonal rabbit (liquid, PBS, azide, gelatin) |
FC, IF, IH(F), IP, WB |
COX-1; no cross reactive with COX-2 |
human, rat, mouse |
COX-1 (poly) IgG
|
Autogen Bioclear
Cat# COX11-A Cat# COX11-C, pos. control supplied by ADI |
immunogen = ram seminal vesicles |
polyclonal rabbit (purified, thimerisol or merthiolate, solution or lyophilized) |
ELISA, WB |
COX-1, no cross reaction with COX-2 |
human, rat, mouse, sheep, ram (other species not tested) |
COX-1 (CXIII) IgG2b
|
Axxora
Cat # ALX-804-030 |
immunogen = sheep seminal vesicle COX-1 |
monoclonal mouse (lyophilized) |
IC, IH(F, P), WB |
COX-1;no cross reaction with Cox-2 except in human (5%) and sheep (50%) |
monkey, human, rat, mouse, sheep, bovine |
COX-1 (poly) IgG
|
Axxora
Cat # ALX-210-710 |
immunogen = synthetic peptide (L M H Y P R G I P P Q) corresp. to aa 272-282 of sheep seminal vesicle COX-1 |
polyclonal rabbit (lyophilized) |
IC, IH, WB |
endothelial COX-1, not COX-2 (human, mouse, sheep) |
human, pig, sheep, bovine (not mouse, rat) |
COX-1 (poly) IgG
|
Axxora
Cat # ALX-210-750 |
immunogen = synthetic peptide, M R Y P P G V P P E R Q M A, corr. to aa 274-288 of mouse COX-1 |
polyclonal rabbit (liquid, affinity purified, TBS, glycerol, BSA, azide) |
IH(P), WB |
COX-1, not COX-2 |
rat, mouse (not human or sheep) |
COX-1 (mono)
|
Biotrend
Cat# COX13-M |
|
monoclonal mouse (Ig fraction) |
|
COX-1 |
human |
COX-1 (mono)
|
Biotrend
Cat# COX14-M |
|
monoclonal mouse (Ig fraction) |
|
COX-1 |
sheep |
COX-1 (poly)
|
Biotrend
Cat# 905-064 |
|
polyclonal rabbit (Ig fraction, affinity purified) |
|
COX-1 |
human |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly)
|
Biotrend
Cat# 905-067 |
|
polyclonal rabbit (Ig fraction, affinity purified) |
|
COX-1 |
rat |
COX-1 (poly)
|
Biotrend
Cat# COX11-A |
|
polyclonal rabbit (Ig fraction) |
|
COX-1 |
sheep |
COX-1 (poly)
|
Biotrend
Cat# COX12-A |
|
polyclonal goat (Ig fraction) |
|
COX-1 |
human |
COX-1 (CX111) IgG2b
|
Cayman Chemical
Cat# 160110 |
immunogen = purified sheep COX-1 |
monoclonal mouse (purified IgG, lyophilized) |
IC, IH, WB |
COX-1; some cross reaction with COX-2 |
monkey, human, rat, mouse, ovine, bovine (murine COX-1, ovine COX-2 (50%), and human COX-2 (~5%), not murine COX-2) |
COX-1 (CX111) IgG2b
|
Cayman Chemical
Cat# 160111 |
immunogen = purified ovine COX-1 |
monoclonal mouse (purified IgG, lyophilized, fluorescin [FITC]) |
FC |
COX-1; some cross reaction with COX-2 |
human, rat, mouse, bovine (murine COX-1, ovine COX-2 (50%), and human COX-2 (~5%), not murine COX-2) |
COX-1 (CX111) IgG2b
|
Cayman Chemical
Cat# 160120 |
immunogen = purified ovine COX-1 |
monoclonal mouse (IgG, PBS, BSA, phycoerythrin [PE]) |
FC |
COX-1; slight cross reaction with COX-2 |
human, rat, mouse, ovine, bovine (murine COX-1, ovine COX-2 (50%), and human COX-2 (~5%), not murine COX-2) |
COX-1 (poly) IgG
|
Cayman Chemical
Cat# 160108 |
immunogen = synthetic peptide, L M H Y P R G I P P Q, from the ovine seminal vesicle COX-1 aa 272-282 |
polyclonal rabbit (IgG, lyophilized) |
IC, IH, WB |
COX-1; no cross reaction with COX-2 |
human, porcine, ovine, bovine (not murine, rat) |
COX-1 (poly) IgG
|
Cayman Chemical
Cat# 160109 |
immunogen = murine COX-1 aa 274-288 (L M R Y P P G V P P E R Q M A) |
polyclonal rabbit (IgG, TBS, BSA, azide, lyophilized, affinity purified) |
IH, WB |
COX-1; no cross reaction with COX-2 |
rat, mouse (not human, ovine) |
COX-1 (mono) IgG2b
|
Chemicon and Upstate are Millipore
Cat# MAB5586 |
immunogen = purified sheep Cox-1 |
monoclonal mouse (liquid, purified Ig, Tris, azide) |
ELISA, WB |
COX-1 |
human, rat, mouse, sheep, bovine (other species not tested) |
COX-1 (M01010923) IgG
|
Europa
Cat# FZ10-C06A supplied by Fitzgerald data sheet |
immunogen = highly pure Human COX-1 |
monoclonal mouse (ascites, affinity purified, PBS, azide) |
ELISA, IH, WB |
COX-1, ovarian/cervical |
human |
Antigen (Clone) IgG |
Distributor (Producer) |
Immunogen (Epitope) |
Host (Formulation) |
Methods glossary |
Specificity |
Reactivity top |
COX-1 (poly)
|
Everest Biotech Ltd
Cat# EB05285 |
immunogen = peptide with sequence C-Q D D G P A V E R P S T E L, from C terminus of the protein sequence |
polyclonal goat (liquid, affinity purified, BSA, Tris saline, azide) |
WB |
both human isoforms of the COX-1 protein; ~ 65-70kDa bands |
human |
COX-1 (AS70) IgG1
|
Exalpha Biologicals
Cat# A091M |
|
monoclonal mouse (purified, sterile filtered, PBS, azide) |
EIA |
COX-1 |
human |
COX-1 (M01010923) IgG1
|
Fitzgerald
Cat# 10-C06A |
immunogen = highly pure Human COX-1 |
monoclonal mouse (ascites, affinity purified, PBS, azide) |
ELISA, IH, WB |
COX-1, ovarian/cervical |
human |
COX-1 (12E12) IgM
|
GeneTex
Cat# GTX10938 |
immunogen = prokaryotic recombinant protein corresp. to 120 aa of the N-terminus of the human COX-1 molecule |
monoclonal mouse (liquid, supernatant, azide) |
IH(P) |
Cox-1
|
human (others not tested) |
COX-1 (5F6/F4) IgG1, κ
|
GeneTex
Cat# GTX20695 |
immunogen = a preparation of intracellular proteins of the human cell line HL60n COX-1 molecule |
monoclonal mouse (liquid, affinity purified, PBS, azide) |
ELISA, WB |
Cox-1; no cross reaction with Cox-2
|
human, mouse (others not tested) |
COX-1 (AS70) IgG1
|
GeneTex
Cat# GTX16116 |
immunogen = unfortunately, this information is considered to be commercially sensitive |
monoclonal mouse (liquid, azide) |
EIA |
Cox-1 |
human (other species not tested) |
COX-1 (poly) IgG
|
GeneTex
Cat# GTX22338 |
immunogen = peptide with sequence Q D D G P A V E R P S T E L, from C-Terminus of the protein sequence NP_000953; NP_542158 |
polyclonal goat (liquid, affinity purified, BSA, TBS, azide) |
WB |
recognises both human isoforms of this protein
|
human (others not tested) |
COX-1 (12E2) IgM
|
Histo-Line
Cat# Mob412 supplied by Diagnostic Biosystems |
immunogen = prokaryotic recomb. protein corr. to 120 aa of the N-terminus of human COX-1 |
monoclonal mouse (supernate, azide) |
IH |
COX-1, cytoplasmic |
human |
COX-1 (COX111) IgG2b
|
Histo-Line
Cat# 18-7381 supplied by Zymed |
immunogen = Ram testis |
monoclonal mouse (purified ascites, BSA, PBS, azide) |
IH(F, P) |
COX-1, cytoplasmic |
|
COX-1 (COX111) IgG2b
|
Histo-Line
Cat# 35-8100 supplied by Zymed |
immunogen = Ram testis |
monoclonal mouse (protein-A purified ascites, BSA, PBS, azide) |
ELISA, IF, IH(F, P), WB |
72 kDa COX-1, moderate cross with ovine COX-2, slight cross with human COX-2 |
human, rat, mouse, ovine |