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Keywords:
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Search Results:
Antigen Class
=TAR DNA-binding protein /TDP-43
Narrow Results
Host:
Method:
Species Reactivity:
Distributor:
-- select --
mouse
rabbit
rat
----------------
all monoclonal
all polyclonal
-- select --
ELISA
IB
IC
IF
IH
IH(F)
IH(P)
IP
WB
and
-- select --
chicken
frog
human
monkey
mouse
primate (various)
rat
xenopus
zebra fish
and
-- select --
Abcam Ltd
Abnova Corporation
Cosmo Bio USA, Inc.
Novus Biologicals, I
Proteintech Group, I
exclude selected host
-- select --
ELISA
IB
IC
IF
IH
IH(F)
IH(P)
IP
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-- select --
chicken
frog
human
monkey
mouse
primate (various)
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xenopus
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1 to 27 of 27 results
Important Notice:
We are striving to include as many companies or products as possible, but we do not make a claim to being comprehensive. We may inadvertently omit specific companies or products due to a lack of information.
Antibodies to TAR DNA-binding protein
From the Laboratories
Antigen
(Clone)
IgG
Name
(Source)
used in
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
TARDPB /TDP-43
(poly)
N-terminal antibody
(
Virginia M.-Y. Lee
, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine)
Reference:
Winton, 2008
immunogen = synthetic peptide near the N-terminus of human TDP-43 corresp. to amino acid residues 6-24
polyclonal rabbit
IB
TARDBP, N terminal
human
TARDPB /TDP-43
(poly)
C-terminal antibody
(
Virginia M.-Y. Lee
, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine)
Reference:
Winton, 2008
immunogen = an extreme C-terminal synthetic peptide, corresp. to the aa residues 394-414 of human TDP-43
polyclonal rabbit
IB
TARDBP, C terminal
human
TDP-43 phos Ser409/410
(1D3, 7A9)
IgG
2a
C-terminal antibody
(
Virginia M.-Y. Lee
, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine)
Paper
Reference:
Gijselinck, 2010
immunogen = phosphopeptide pS409/410 (SMDSKS(p)S(p)GWG), corresp. to amino acid residues 404-413 of human TDP-43, coupled to BSA or ovalbumin.
monoclonal rat
IB, IF, IH
detects C-terminal TDP-43 phosphorylated at Serine 409 and 410, not with the non- phosphorylated peptide and not with physiologic TDP-43; labels all types of pathologic inclusions, such as NCI, CGIs, NII, DN previously described with phosphorylation-independent TDP-43 antibodies
human, mouse
From the Manufacturers
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
TAR DNA-binding protein
(k1B8)
IgG
1
Novus Biologicals
NBP1-04347
immunogen = recombinant human TARDBP (1-260aa) purified from E. coli
monoclonal mouse
(liquid, PBS, azide)
ELISA, IH, WB
detects TARDBP
human
(others not tested)
TAR DNA-binding protein
(poly)
IgG
Novus Biologicals
NB110-55376
Reference:
Wegorzewska, 2009
immunogen = synthetic peptide to a C-terminal region (within residues 350-414) of the human TARDBP protein
polyclonal rabbit
(affinity purified antisera, Tris-glycine, saline azide)
WB
detects TARDBP, band is seen at ~45 kDa in WB
human, primate (various), mouse, zebra fish, xenopus, chicken
(others not tested)
TARDPB /TDP-43
(mono)
IgG
1
,κ
Abcam
ab57105
immunogen = recombinant full length protein, corresponding to amino acids 1-261 of Human TARDBP
monoclonal mouse
(liquid, protein-G purified, PBS, no preservative)
IC, IF,
IH(P)
, WB
45kDa TARDBP
human
(others not tested)
TARDPB /TDP-43
(poly)
IgG
Abcam
ab50930
immunogen = region within synthetic peptide: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC, corresponding to N terminal amino acids 1-50 of Human TARDBP
polyclonal rabbit
(liquid, protein-A purified, sucrose, PBS, no preservative)
IH(P)
, WB
45kDa TARDBP
human
TARDPB /TDP-43
(poly)
IgG
Abcam
ab41881
immunogen = synthetic peptide: conjugated to KLH derived from within residues 350 to the C-terminus of Human TARDBP
polyclonal rabbit
(liquid, Tween 20, saline, HEPES, EDTA, no preservative)
IC, IF, IP, WB
detects TARDBP
human
TARDPB /TDP-43
(poly)
IgG
Abcam
ab82695
immunogen = synthetic peptide: within residues GISVHISNAE PKHNSNRQLE RSGRFGGNPG GFGNQGGFGN SRGGGAGLGN , corresponding to internal sequence amino acids 251-300 of Human TARDBP
polyclonal rabbit
(liquid, affinity purified, sucrose, PBS, no preservative)
ELISA, WB
detects TARDBP
human, mouse
TARDPB /TDP-43
(poly)
IgG
Abcam
ab41972
immunogen = synthetic peptide: conjugated to KLH derived from within residues 250 - 350 of Human TARDBP
polyclonal rabbit
(liquid, affintiy purified, PBS, BSA, azide)
IC, IF,
IH(F)
, WB
detects TARDBP
human, rat
(expect mouse, chick, cow)
TARDPB /TDP-43
(poly)
IgG
Abcam
ab42474
immunogen = synthetic peptide: conjugated to KLH derived from within residues 150-250 of Rat TARDBP
polyclonal rabbit
(liquid, affintiy purified, PBS, BSA, azide)
IC, IF,
IH(P)
, WB
detects TARDBP
human, rat, mouse
(expect chicken, cow)
TARDPB /TDP-43
(1B4-B1)
IgG
1
,κ
Abnova Corporation
Cat# H00023435-M02
immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag.
monoclonal mouse
(liquid, PBS)
ELISA, WB
recognizes human TDP-43, recombinant protein
human
TARDPB /TDP-43
(2E2-D3)
IgG
1
,κ
Abnova Corporation
Cat# H00023435-M01
References:
Steinacker, 2008
Zhang, 2008
, epitope mapping.
Winton, 2008
immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag. (epitope at aa 205-222)
monoclonal mouse
(liquid, PBS)
ELISA, IF, IH, WB
recognizes aa 205–222 of human TDP-43, correspond. to a part of the second RNA recognition motif (RRM2);
also recognizes 25 kDa C-terminal fragments
human
(
not
mouse or rat)
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
TARDPB /TDP-43
(k1B8)
IgG
1
,κ
Abnova Corporation
Cat# MAB2040
immunogen = recombinant protein corresponding to amino acids 1-260 of human TARDBP
monoclonal mouse
(liquid, PBS, azide)
ELISA, IH, WB
recognizes human TDP-43, recombinant protein
human
TARDPB /TDP-43
(poly)
Abnova Corporation
Cat# H00023435-A01
immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag.
polyclonal mouse
(liquid, glycerol)
ELISA, WB
detects human TDP-43, cell lysate or recombinant protein
human
TARDPB /TDP-43
(poly)
Abnova Corporation
Cat# PAB12006
immunogen = a synthetic peptide selected within amino acids 350-414 of human TARDBP
polyclonal rabbit
(liquid, Tris/glycine, saline, azide)
WB
detects human TDP-43, cell lysate
monkey, human, mouse, zebra fish, frog, chicken
TARDPB /TDP-43
(mono)
IgG
1
Proteintech Group, Inc.
60019-2-Ig
Reference:
Brouwers, 2007
immunogen = recombinant Protein
monoclonal mouse
(liquid, purified, PBS, azide, glycerol)
ELISA, IH, WB
recognizes 45kDa TARDBP
human
(others not tested)
TARDPB /TDP-43
(mono)
IgG
2b
Proteintech Group, Inc.
Cat# 60019-1-Ig
immunogen = recombinant Protein
monoclonal mouse
(liquid, purified, PBS, azide, glycerol)
ELISA, IH, WB
recognizes 43kDa TARDBP
human
(others not tested)
TARDPB /TDP-43
(poly)
IgG
Proteintech Group, Inc.
10782-2-AP
References:
(
Liu-Yesucevitz, 2010
, unspecified immunogen)
Wegorzewska, 2009
Rademakers, 2008
Steinacker, 2008
Zhang, 2008
Winton, 2008
immunogen = recombinant Protein (raised to aa 1-260)
polyclonal rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB
detects 43kDa TARDBP
human, rat, mouse
TARDPB /TDP-43
(poly)
IgG
Proteintech Group, Inc.
12892-1-AP
immunogen = TAR DNA binding protein, C-terminal 154aa of BC001487
polyclonal rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB
detects 45kd full length protein and the truncated 25kd protein
human, mouse
(others not tested)
TARDPB /TDP-43
(poly)
IgG
Proteintech Group, Inc.
18280-1-AP
immunogen = full length 414 aa TARDBP protein
polyclonal rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB
detects TAR DNA binding protein
human
(others not tested)
TDP-43
(poly)
Cosmo Bio USA, Inc.
Cat# TIP-PTD-P09
Reference:
Liu-Yesucevitz, 2010
immunogen = TDP-43 aa. 405-414, (CMDSKSSGWGM)
polyclonal rabbit
(liquid, antiserum, azide)
ELISA, IH, WB
recognizes the C-terminus of 43kDa TDP-43
human, rat
TDP-43 phos Ser409
(poly)
Cosmo Bio USA, Inc.
Cat# TIP-PTD-P03
immunogen = CMDSKS(p)SGWGM, S(p):phosphoserine 409
polyclonal rabbit
(liquid, antiserum, azide)
ELISA, IH, WB
reacts with phosphorylated full-length TDP-43 at 45 kDa by WB; NCIs and DNs in dentate gyrus of FTLD-U
human
Antigen
(Clone)
IgG
Distributor
(Producer)
Immunogen
(Epitope)
Host
(Formulation)
Methods
glossary
Specificity
Reactivity
top
TDP-43 phos Ser409/410
(11-9)
IgG
1
Cosmo Bio USA, Inc.
Cat# TIP-PTD-M01
immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410
monoclonal mouse
(liquid, supernatant, azide)
ELISA, IH, WB
recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; stains ubiquitin-positive inclusions in FTLD-U and ALS without nuclear staining; does not stain ghost tangles and granulovacuolar degeneration in AD or other related diseases
human
TDP-43 phos Ser409/410
(poly)
Cosmo Bio USA, Inc.
Cat# TIP-PTD-P01
immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410
polyclonal rabbit
(liquid, antiserum, azide)
ELISA, IH, WB
recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; sometimes stains ghost tangles and dot-like structures (granulovacuolar degeneration) in the hippocampal and other regions of brains with AD or other related diseases.
human
TDP-43 phos Ser409/410
(poly)
Cosmo Bio USA, Inc.
Cat# TIP-PTD-P02
immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410
polyclonal rabbit
(liquid, antiserum, azide)
ELISA, IH, WB
recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; stains ubiquitin-positive inclusions in FTLD-U and ALS without nuclear staining; does not stain ghost tangles and granulovacuolar degeneration in AD or other related diseases
human
TDP-43 phos Ser410
(poly)
Cosmo Bio USA, Inc.
Cat# TIP-PTD-P04
immunogen = CMDSKSS(p)GWGM, S(p):phosphoserine 410
polyclonal rabbit
(liquid, antiserum, azide)
ELISA, IH, WB
reacts with phosphorylated full-length TDP-43 at 45 kDa by WB; NCIs and DNs in dentate gyrus of FTLD-U
human
1 to 27 of 27 results
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