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Home: Research: Compendia: Antibodies
 Antibody Directory
Initial Search
Antigen Class:   
(plus) Keywords:   any keywords all keywords
 Search Results: Antigen Class=Prion protein
Narrow Results
Host: Method: Species Reactivity: Distributor:
  and   and
exclude selected host
 
1 to 16 of 16 results
Important Notice: We are striving to include as many companies or products as possible, but we do not make a claim to being comprehensive. We may inadvertently omit specific companies or products due to a lack of information.
Antibodies to Prion proteins
From the Laboratories
Antigen
(Clone)
IgG		 Name
(Source)
used in		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
PrP
(12B2)
 Reference:
Dossena, 2008
(provided by Jan PM Langeveld, CIDC-Lelystad, the Netherlands)		 immunogen = bovine PrP aa 97-115, corresp to ovine PrP sequence 89–107, conj to KLH at C-terminus. (epitope at 93WGQGG97)  monoclonal mouse
 		 IH, WB  recognizes PrP, PK-cleavage site specific  ovine, bovine
(Reference:
Langeveld, et al., 2006) 
PrP
(SA65)
 SA65
Reference:
Dossena, 2008
(provided by Gianluigi Zanusso, Department of Neurological and Visual Sciences, University of Verona)		 immunogen = recombinant human PrP23–231; epitope in alpha-helix 1 of PrP  monoclonal mouse
 		 EM, IH(P), WB  recognizes all glycoforms of PrP  human, rat, mouse, ovine, bovine
(Reference:
Matucci, et al., 2005) 
PrP
(poly)
IgM 		P45-66
Reference:
Dossena, 2008
(provided by David Harris, Washington University in St. Louis)		 raised against synthetic peptide-encompassing mouse PrP (MoPrP) residues 45 to 66  polyclonal rabbit
 		 EMSA, IP, WB  recognizes PrP  mouse
(Reference:
Lehmann, Harris, 1995) 
PrPSc and recPrP
(6D11)
IgG2a,κ 		6D11
(R.J. Kascsak, Department of Neurology, New York University School of Medicine, New York, NY
Paper, DS Spinner, 2007)
Reference:
E Chung, 2010		 Prnp-/- mice were immunized with nondenatured 139A scrapie-associated fibrils (SAF) and with ODN 1826  monoclonal mouse
(liquid, tissue-culture supernatant or ascites, purified) 		 ELISA, IH, WB  reacts with the N-terminal epitope residues 97-100, QWNK, in native and denatured forms of PrPSc and recombinant PrP  human, mouse, hamster, ovine, bovine, elk, mule deer 
PrPSc
(15B3)
IgM 		Reference:
Dossena, 2008
(provided by Alex Raeber and Bruno Oesch, Prionics, Zurich)		 (three polypeptide segments responsible for the 15B3 epitope: 15b3-1 involves residues 142-148 GSDYEDR(YY); 15b3-2 residues 162-170 YYRPVDQYS;15b3-3 residues 214-226 CITQYQ RESQAYY)  monoclonal mouse
 		 IP, WB  recognizes both protease resistant and protease sensitive forms of abnormal, disease associated PrP  human, mouse, bovine
(Reference:
Korth, et al., 1997) 
From the Manufacturers
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
prion protein
(34C9)
IgG2b,κ 		Cat# 01-020, 01-021 epitope within position 138-142 with numbering according to the human PrP  monoclonal mouse
(liquid, culture supernatant; serum-free medium, azide) 		 WB  mAB 34C9 recognizes the sequence LIHFG in the bovine prion protein. This sequence is conserved in bovine, rabbit, pig, and mule deer PrP sequences but not in human, mouse or hamster PrP  rabbit, pig, bovine, deer
(not human, mouse, hamster) 
prion protein
(6H4)
IgG1,κ 		Cat# 01-010, 01-011
Reference:
Parkin, 2007		 The epitope falls within amino acids 144-152, (DYEDRYYRE) of human prion protein  monoclonal mouse
(liquid, serum-free medium, azide) 		 ELISA, IH, WB  mAB 6H4 recognizes the sequence DYEDRYYRE in the prion protein; reacts on Western blots with mouse and hamster PrP, indicating that the substitution at position 145 does not prevent binding of 6H4  human, mammal (various) 
prion protein
(6H4)
IgG2b,κ 		Cayman Chemical
Cat# 189720
Reference:
Parkin, 2007		 immunogen = a preparation of SAF (scrapie associated fibrils) from infected hamster brain  monoclonal mouse
(lyophilized IgG) 		 ELISA, FC, IH, WB  recognizes the octo-repeat region located in the N-terminal region of PrP  human, mouse, hamster, ovine, bovine 
prion protein
(3F4)
IgG2A 		Signet Covance
Cat# SIG-39600		 epitope lies within amino acids 109-112 of prion protein  monoclonal mouse
(liquid, ascites,) 		 ELISA, IH, IP, WB  3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing)  human, hamster, cat
(paper, Kascsak, et al., 1987) 
prion protein
(3F4)
IgG2A 		Signet Covance
Cat# SIG-39620
References:
Gijselinck, 2010
Parkin, 2007		 epitope lies within amino acids 109-112 of prion protein  monoclonal mouse
(liquid, purified, PBS,) 		 ELISA, IH, IP, WB  3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing)  human, hamster, cat
(paper, Kascsak, et al., 1987) 
prion protein
(3F4)
IgG2A 		Signet Covance
Cat# SIG-39640		 epitope lies within amino acids 109-112 of prion protein  monoclonal mouse
(liquid, purified, PBS, biotin conj.) 		 ELISA, IH, IP, WB  3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing)  human, hamster, cat
(paper, Kascsak, et al., 1987) 
prion protein
(4B4)
IgG1 		Signet Covance
Cat# SIG-39802		 The epitope site appears to be non-linear (discontinuous).  monoclonal mouse
(supernatant, purified, PBS, no preservatives or carrier proteins) 		 ELISA, IF, IH, WB  This antibody recognizes both the cellular (protease sensitive) and infectious (protease resistant) isoforms of PrP  rabbit, sheep, cat 
prion protein
(6D11)
IgG2A,κ 		Signet Covance
Cat# SIG-39810		 The epitope falls within amino acids 93-109 of PrP  monoclonal mouse
(liquid, affinity purified, PBS, no preservatives or carrier proteins) 		 ELISA, IB, IH(P)  6D11 reacts with both the PrPc and PrPsc forms  human, mouse, hamster, sheep, mule, bovine, elk, deer 
prion protein
(7D9)
IgG1 		Signet Covance
Cat# SIG-39805		 Immunogin within recombinant mouse PrP protein, aa 23-237  monoclonal mouse
(supernatant, purified, PBS, no preservatives or carrier proteins) 		 ELISA, IH, WB  7D9 reacts exceptionally well with bovine, sheep, and mouse PrP. It is 10 fold less reactive to feline, hamster, and human PrP. 7D9 recognizes both protease sensitive and protease resistant forms of PrP  mouse, sheep, bovine 
PRNP
(poly)
IgG 		Novus Biologicals
Cat# NB100-40809		 immunogen = synthetic peptide, C-SDYEDRYYREN, representing the internal region of the human protein  polyclonal goat
(affinity purified antisera, Tris-saline, BSA, azide) 		 ELISA, WB  specific for the prion protein; 25kDa band in WB  human
(expect mouse, rat and canine) 
Antigen
(Clone)
IgG		 Distributor
(Producer)		 Immunogen
(Epitope)		 Host
(Formulation)		 Methods
glossary		 Specificity      Reactivity     top
PrP (Major Prion Protein)
(EP1802Y)
IgG 		Novus Biologicals
Cat# NB110-57436		 immunogen = synthetic peptide corresponding to residues near the C-terminus of human Prp  monoclonal rabbit
(ascites, Tris-glycine, saline, glycerol, BSA, azide) 		 FC, IC, IH, WB  Specific for PrP  human, rat, mouse
(others not tested) 
1 to 16 of 16 results
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