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ALZGENE

The AlzGene database is a collection of published genetic association studies performed on AD phenotypes. The database includes summaries of key characteristics of the investigated populations, as well as genotype distributions in cases and controls. AlzGene also provides continuously updated random-effects meta-analyses for polymorphisms with genotype data in at least three case-control samples.

ANTIBODIES

The most comprehensive collection on the web of neuroscience-related
antibodies from commercial and nonprofit sources. Antigen-specific
antibodies are listed in easy-to-scan tables, and each product is linked
to a detailed datasheet.

BIOMARKERS

Our Biomarkers section includes links to the ACS database, Telemakus knowledge base, Antecedent Biomarker workshop summaries, and WashU database.

MUTATIONS

A listing of all of the reported mutations in amyloid-beta precursor
protein (AβPP), presenilin-1 (PS1) and presenilin-2 (PS2)—the three
known genetic causes of autosomal dominant, familial Alzheimer disease—as well as mutations in the tau gene that cause inherited frontotemporal
dementia with Parkinsonism (FTDP).

PATHWAYS

This Pathways Compendium provides an index of Alzheimer disease pathway models contributed by researchers and companies.

RESEARCH MODELS

An inventory of research models that are relevant to understanding Alzheimer
disease. We provide a central publication forum for quickly reporting
and updating data on all published models. Related models are grouped
into tables to facilitate comparisons of different models and to provide
information on the availability of each model.

PROTOCOLS

Search our protocols and reagents database to find experimental protocols that are central to the progress of Alzheimer research. These include protocols for preparing tissues and cell cultures, purifying and identifying biomolecules that may play a role in disease pathogenesis, methods for working with various model systems, imaging studies and behavioral assays.

VIDEO GALLERY

View exclusive short films from "The Alzheimer's Project," sponsored by HBO Documentary Films and other sponsors to see some of the leading scientists in academia and drug development speak directly to key issues in AD research today.
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