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Home: Research: AD Hypotheses
AD HYPOTHESES

SWAN ALZHEIMER KNOWLEDGE BASE
AlzSWAN is a community-driven knowledge base of Alzheimer disease that enables researchers to submit and annotate scientific hypotheses, claims, data, and information, putting these into the context of testable hypotheses and treatment discovery. The system is powered by SWAN (Semantic Web Application in Neuromedicine), which uses Semantic Web technology, to tie together statements made in scientific publications or on the Web to scientific evidence, biological terminologies, and knowledge bases, and to claims and counterclaims made by other researchers.

Please view this tutorial [.pdf] to learn about the functions and features of AlzSWAN.

We welcome your feedback. Seedling hypotheses and observations that are not yet fleshed out scientifically are posted on the Hypothesis Factory page.


CURRENT HYPOTHESES
This is a collection of virtual seminars, online journal club discussions, recorded talks and other presentations on the Alzforum website that describe a variety of scientific hypotheses about the pathogenesis of Alzheimer disease. Readers are invited to submit commentaries on the posted hypotheses and contribute ideas about how these diverse hypotheses and data could be integrated into a more complete picture of the disease. A more extensive collection of hypotheses is being annotated for the SWAN Alzheimer Knowledge Base (see above). The ability to comment on SWAN claims will be available soon.


HYPOTHESIS FACTORY
Our Hypothesis Factory is devoted to the presentation and exchange of ideas regarding novel hypotheses, hunches, theories-in-progress, and wild speculation. It provides a forum where people can publicly present and discuss unconventional ideas, medical anecdotes, and other informal types of information that may nonetheless provide useful insights.

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AlzSWAN Knowledge Base

AlzSWAN enables researchers to annotate scientific hypotheses, claims, data and information, putting these into the context of testable hypotheses and treatment discovery. Please sign up if you would like to post comments about AlzSWAN claims and hypotheses.

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An up-to-date collection of all published AD genetic association studies.
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